Induction of tumour necrosis factor alpha in experimental animals treated with hepatotoxicants.

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dc.contributor.authorRoy, Aen_US
dc.contributor.authorSoni, G Ren_US
dc.contributor.authorKolhapure, R Men_US
dc.contributor.authorBanerjee, Ken_US
dc.contributor.authorPatki, P Sen_US
dc.date.accessioned2009-05-28T11:22:24Z
dc.date.available2009-05-28T11:22:24Z
dc.date.issued1992-08-01en_US
dc.description.abstractAdministrations of hepatotoxicants namely carbon tetrachloride (CCl4:0.4 ml in 1.2 ml of liquid paraffin) and ANIT (1 ml of 1.5% solution in liquid paraffin) in Charles foster rats (force fed) and D-galactosamine (8 mg in water per swiss albino mouse, ip) induce the release of TNF-alpha in case of CCl4 and D-galactosamine. High TNF-alpha level was observed up to 48 hr in CCl4 and up to 24 hr in D-galactosamine treated animals. Elevated levels of biochemical like ALP and SGPT are also recorded. TNF-alpha level can be measured of tissue damage and prognosis in case of hepatitis.en_US
dc.description.affiliationNational Institute of Virology, Pune, India.en_US
dc.identifier.citationRoy A, Soni GR, Kolhapure RM, Banerjee K, Patki PS. Induction of tumour necrosis factor alpha in experimental animals treated with hepatotoxicants. Indian Journal of Experimental Biology. 1992 Aug; 30(8): 696-700en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56624
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.mesh1-Naphthylisothiocyanate --pharmacologyen_US
dc.subject.meshAlanine Transaminase --blooden_US
dc.subject.meshAlkaline Phosphatase --blooden_US
dc.subject.meshAnimalsen_US
dc.subject.meshCarbon Tetrachloride --pharmacologyen_US
dc.subject.meshGalactosamine --pharmacologyen_US
dc.subject.meshLiver --drug effectsen_US
dc.subject.meshMiceen_US
dc.subject.meshRatsen_US
dc.subject.meshTumor Necrosis Factor-alpha --biosynthesisen_US
dc.titleInduction of tumour necrosis factor alpha in experimental animals treated with hepatotoxicants.en_US
dc.typeJournal Articleen_US
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