Comparison of Anthropometry, Insulin Resistance and Lipid Parameters in Nondiabetics with and without Family History of Type 2 Diabetes Mellitus.

Simple item page
dc.contributor.authorG, Dayananda
dc.contributor.authorDevi, Kusuma
dc.contributor.authorMurthy, Niranjan
dc.contributor.authorKumaran, Sendil
dc.date.accessioned2016-02-10T05:16:24Z
dc.date.available2016-02-10T05:16:24Z
dc.date.issued2013-04
dc.description.abstractType 2 DM is a complex metabolic syndrome characterized by impaired insulin secretion and insulin resistance (IR). IR has a strong genetic component and the children of diabetics have an increased risk for the early onset of DM.The body mass index (BMI), waist circumference (WC), blood pressure (BP), fasting plasma glucose (FPG), fasting plasma insulin (FPI), HOMA-IR (Homeostatic model assessment - IR) and lipid parameters were measured and statistically compared in 25 nondiabetics with family history of type 2 DM (FH + group) and 25 age matched nondiabetics without family history of type 2 DM (FH - group).The FPI (8.76 ± 3.6), HOMA-IR (1.95 ± 0.86) and serum triglycerides (136.43 ± 11.44) were statistically significant (p<0.05) in the FH + group when compared to the FH - group. WC, total cholesterol and BP showed a trend towards increase in the FH + group. There is hyperinsulinemia, IR and an altered lipid metabolism in the FH + group. The complex genetic predisposition to IR and its association with the increasing WC in the FH + group predisposes such individuals to the development of type 2 DM.en_US
dc.identifier.citationG Dayananda, Devi Kusuma, Murthy Niranjan, Kumaran Sendil. Comparison of Anthropometry, Insulin Resistance and Lipid Parameters in Nondiabetics with and without Family History of Type 2 Diabetes Mellitus. JK Science Journal of Medical Education and Research. 2013 Apr-June 15(2): 59-62.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/172256
dc.language.isoenen_US
dc.source.urihttps://www.jkscience.org/archives/volume145/Article1.pdfen_US
dc.subjectBody Mass Indexen_US
dc.subjectType 2 Diabetes Mellitusen_US
dc.subjectWaist Circumferenceen_US
dc.titleComparison of Anthropometry, Insulin Resistance and Lipid Parameters in Nondiabetics with and without Family History of Type 2 Diabetes Mellitus.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
jksjmer2013v15n2p59.pdf
Size:
88.2 KB
Format:
Adobe Portable Document Format
Description:
Original Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
JK Science Journal of Medical Education and Research