Insulin Secretory Status in Obese Female.
| dc.contributor.author | Tasnim, Masuma | |
| dc.contributor.author | Akhter, Qazi Shamima | |
| dc.contributor.author | Akhter, Salma | |
| dc.contributor.author | lovely, Nasreen Sultana | |
| dc.contributor.author | Begum, Khadiza | |
| dc.contributor.author | Sinha, Susmita | |
| dc.date.accessioned | 2016-02-08T03:27:47Z | |
| dc.date.available | 2016-02-08T03:27:47Z | |
| dc.date.issued | 2014-12 | |
| dc.description.abstract | Background: In obesity insulin hypersecretion is a key feature indicating the abnormal pancreatic beta cell function which is the fundamental defect in the development of NIDDM, hypertension and cardiovascular diseases. Objective: To assess the secretory status of insulin in adult obese female. Methods: The present study was a cross sectional analytical study and conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2012 to June 2013. 50 obese female subjects of 20-40 years were included from Out-patient Department (Obesity clinic) of BIRDEM Hospital, Dhaka and by personal contact from different areas of Dhaka city. 50 age matched, healthy non-obese female subjects selected as controls . Fasting serum insulin level was measured by ELISA and fasting glucose level was measured by Glucose oxidase method. The insulin secretory status was calculated by HOMA-%B using HOMA software. For statistical analysis unpaired Student’s ‘t’ test and Pearson’s correlation coefficient (r) test were performed as applicable . Result: Mean fasting serum insulin and HOMA%B (P<0.001) were higher in the obese than that non obese. Fasting serum insulin level and HOMA%B showed significantly positive correlation with WHR. Conclusion: This study concludes that obese individual develops a state of insulin hypersecretion and hyperinsulinemia. | en_US |
| dc.identifier.citation | Tasnim Masuma, Akhter Qazi Shamima, Akhter Salma, lovely Nasreen Sultana, Begum Khadiza, Sinha Susmita. Insulin Secretory Status in Obese Female. Journal of Bangladesh Society of Physiologists. 2014 Dec; 9(2): 72-77. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/171994 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.banglajol.info/index.php/JBSP/article/view/22800 | en_US |
| dc.subject | Obesity | en_US |
| dc.subject | HOMA-%B | en_US |
| dc.subject | Hyperinsulinemia | en_US |
| dc.title | Insulin Secretory Status in Obese Female. | en_US |
| dc.type | Article | en_US |