Measurement of HDL-cholesterol in serum by a new enzymatic method.

dc.contributor.authorTangvarasittichai, Surapon
dc.contributor.authorTaytiwat, Prawit
dc.date.accessioned2012-03-30T05:50:54Z
dc.date.available2012-03-30T05:50:54Z
dc.date.issued2001-07
dc.description.abstractHigh density lipoprotein (HDL) are responsible for the reverse transport of cholesterol from the peripheral cells to the liver. Here, cholesterol is metabolised. Monitoring of HDL-C in serum is of clinical importance since an inverse correlation exists between serum HDL-C concentrations and the risk of atheroselerotic disease. Elevated HDL-C concentrations are protective against coronary heart disease. In this study, an automated enzymatic method for the direct determination of HDL-C in serum was found to have good precision and accuracy. Reproducibility was determined daily using control precinorm? L in an internal protocol (n=20), within-run CV = 1.3% and between-day CV = 2.013%. The comparison of the HDL-C enzymatic assay with HDL-C precipitating agent was good with a correlation coefficient r = 0.965, Y = 1.981+ 0.959X, n =172. The normal range of HDL-C concentration in serum by this enzymatic method was 36.16 -86.08 mg./dl. Thus, a HDL-C level of over 35 mg/dl., shows the risk is not high and is protective against coronary heart disease.en_US
dc.identifier.citationTangvarasittichai Surapon, Taytiwat Prawit. Measurement of HDL-cholesterol in serum by a new enzymatic method. Siriraj Medical Journal, 2001 Jul; 53(7): 414-419.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/137400
dc.language.isoenen_US
dc.source.urihttps://www.sirirajmedj.com/content_download.php?content_id=902en_US
dc.subjectHDL-cholesterolen_US
dc.subjectNew enzymatic methoden_US
dc.titleMeasurement of HDL-cholesterol in serum by a new enzymatic method.en_US
dc.typeArticleen_US
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