Isolated angiokeratomas of the tongue: A rare entity

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dc.contributor.authorHamid, Rizwanen_US
dc.contributor.authorChalkoo, Altaf Hen_US
dc.contributor.authorSingh, Inderpreeten_US
dc.contributor.authorWani, Suhailen_US
dc.contributor.authorBilal, Sheikhen_US
dc.date.accessioned2020-01-02T06:46:14Z
dc.date.available2020-01-02T06:46:14Z
dc.date.issued2019-03
dc.description.abstractAngiokeratomas consist of ectasias of dermal capillaries associated with an acanthotic and hyperkeratotic overlying epidermis. These dark red-to-purple, papular vascular anomalies can vary considerably in size, depth, and location. It is a skin disorder that rarely involves oral cavity. It can occur in localized or generalized form and is often associated with underlying metabolic disorder such as Fabry's disease and fucosidosis. It has many clinical variants with the same underlying histopathology. Mucosal involvement, including the oral cavity, is occasionally found either as a component of the systemic variety, called angiokeratoma corporis diffusum, or associated with cutaneous lesions in more locations. Isolated oral involvement seems to be rather infrequent, and only eighteen cases have been described in the world literature thus far. Isolated multiple angiokeratomas of tongue without plaque formation have been reported only four times before this. Here, we report a fifth case of isolated multiple angiokeratomas of tongue in a 16-year-old female which was confirmed by immunohistochemical pattern in consonance with a blood vessel origin, with expression of CD31, CD34, and von Willebrand factor. The lesion did not express D2-40 and CD45. No other malformation or metabolic disorder was found in the patient.en_US
dc.identifier.affiliationsDepartment of Oral Medicine and Radiology, Government Dental College and Hospital, Srinagar, Jammu and Kashmir, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, SKIMS, Srinagar, Jammu and Kashmir, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, GMC, Srinagar, Jammu and Kashmir, Indiaen_US
dc.identifier.citationHamid Rizwan, Chalkoo Altaf H, Singh Inderpreet, Wani Suhail, Bilal Sheikh. Isolated angiokeratomas of the tongue: A rare entity. Indian Journal of Dental Research. 2019 Mar; 30(2): 322-326en_US
dc.identifier.issn0970-9290
dc.identifier.issn1998-3603
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/192234
dc.languageenen_US
dc.publisherIndian Society for Dental Researchen_US
dc.relation.issuenumber2en_US
dc.relation.volume30en_US
dc.source.urihttps://dx.doi.org/10.4103/ijdr.IJDR_644_17en_US
dc.subjectAngiokeratomaen_US
dc.subjectimmuno‑histochemicalen_US
dc.subjectisolateden_US
dc.subjectoral cavityen_US
dc.subjecttongueen_US
dc.subjecttumoren_US
dc.titleIsolated angiokeratomas of the tongue: A rare entityen_US
dc.typeJournal Articleen_US
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