Cerebellar granule cell membranes and glutamate mediates transactivation of glutamine synthetase promoter.

No Thumbnail Available
Date
1997-02-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Potential region of glutamine synthetase promoter driving astrocyte-specific transactivation, mediated by cerebellar granule cell membrane and glutamate has been identified by deletion analysis of promoter and transient transfection. The promoter region from -420 to -765 was found to be potentially important for this transactivation. These results provided further evidence for importance of neuronal-glial and glutamate-glial interactions in regulation of glial gene expression.
Description
Keywords
Citation
Kedar V, Purohit H, Freeze E, Hempel F. Cerebellar granule cell membranes and glutamate mediates transactivation of glutamine synthetase promoter. Indian Journal of Experimental Biology. 1997 Feb; 35(2): 123-7
URI
https://imsear.searo.who.int/handle/123456789/61700
Collections
Indian Journal of Experimental Biology