Role of serum cardiac Troponin-I for risk stratification in first attack in acute myocardial infarction.
| dc.contributor.author | Sahabuddin, Joarder M | |
| dc.contributor.author | Jafarullah, M | |
| dc.contributor.author | Moinuddin, A | |
| dc.date.accessioned | 2015-12-10T11:08:24Z | |
| dc.date.available | 2015-12-10T11:08:24Z | |
| dc.date.issued | 2009-06 | |
| dc.description.abstract | Introduction: Cardiac troponin-I (cTnI) is known to have the highest specificity and analytic sensitivity for detection of myocardial injury; it is used both as diagnostic and prognostic marker. This study was aimed to confirm this idea. Subjects & methods: This prospective observational study included 60 patients of 40 to 65 years age range diagnosed as acute myocardial infarction. The mean ages were 50±8 years and 53±8 years in Q –wave AMI and non Q-wave AMI respectively. Male and female patients included were 86.7% and 13.3%; BMI was 25.3±1.5. Results: Study showed troponin-I 7.53±0.086 ng/ml in Q wave and in non Q-wave AMI was 6.38±0.64 ng/ml after 24 hours of attack of AMI without any significant difference between two groups (P>0.05). The mean troponin-I within 9 hours of attack, were 1.60±0.80 ng/ml and 2.7±1.4 ng/ml in stable and unstable group respectively and the difference found statistically significant (P<0.05). The mean troponin-I between 9-24 hours of attack were 2.90±1.20 ng/ml and 4.90±3.20 ng/ml in stable and unstable group respectively and the difference found statistically significant (P<0.01). The mean troponin-I in unstable group after 24 hours was 9.20±4.30 ng/ml which was more than between 9-24 hours and the difference was significant (P>0.001). In clinicopathological outcome evaluation 37 patients had troponin-I level >1.5 ng/ml in which 29 patients developed unstability and 8 patients were stable. Conclusion: Serum cTnI is better and more characteristic biomarker for risk prediction and prognosis evaluation in AMI patients. | en_US |
| dc.identifier.citation | Sahabuddin Joarder M, Jafarullah M, Moinuddin A. Role of serum cardiac Troponin-I for risk stratification in first attack in acute myocardial infarction. Bangladesh Journal of Medical Science. 2009; 8(3): 57-63. | en_US |
| dc.identifier.issn | 2223-4721 | |
| dc.identifier.issn | 2076-0299 | |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/167807 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.banglajol.info/index.php/BJMS/article/view/3984 | en_US |
| dc.subject | Cardiac Troponin-I | en_US |
| dc.subject | acute myocardial infarction | en_US |
| dc.subject | risk stratification | en_US |
| dc.title | Role of serum cardiac Troponin-I for risk stratification in first attack in acute myocardial infarction. | en_US |
| dc.type | Article | en_US |