Production Optimization of Extracellular L-Asparaginase Through Solid- State Fermentation By Isolated Bacillus Subtilis.
Loading...
Date
2013-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
L-asparaginase has been used as anti-tumor agent for the treatment of acute lymphoblastic
leukemia and food processing aid to reduce the formation of cancer causing acrylamide. Extracellular Lasparaginase
production was optimized through solid state fermentation using ground nut cake by isolated
Bacillus subtilis. which was not reported in literature.Optimum production of L-asparaginase enzyme
(18.4U/ml) was obtained after 48h of incubation at 370C moisture content of 70% and at pH 7.
Description
Keywords
L-asparaginase, Bacillus subtilis, solid- state fermentation
Citation
Shukla Susmita, Mandal S K. Production Optimization of Extracellular L-Asparaginase Through Solid- State Fermentation By Isolated Bacillus Subtilis. International Journal of Applied Biology and Pharmaceutical Technology. 2013 Jan-Mar; 4(1): 219-226.