Clustered regularly interspaced short palindromic repeats cas systems: a comprehensive review.

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dc.contributor.authorMahmud, Shahin
dc.contributor.authorAhmed, Jahir
dc.contributor.authorAziz, Md Abdul
dc.contributor.authorHasan, Mirza Rokibu
dc.contributor.authorShaon, Shoaib Mahmud
dc.contributor.authorBhuiyan, Md Naieem Al-Hasan
dc.contributor.authorRahman, Md Farzanoor
dc.contributor.authorRakib, Hasibul Haque
dc.contributor.authorIslam, Md Shariful
dc.date.accessioned2015-11-05T11:38:53Z
dc.date.available2015-11-05T11:38:53Z
dc.date.issued2015-07
dc.description.abstractThe clustered regularly interspaced short palindromic repeats (CRISPR) system was recently identified as a bacterial defense mechanism against phages and plasmids. The CRISPR system is composed of DNA arrays containing short sequences identical to those present in phages and plasmids. These short DNAs are transcribed and processed by CRISPR associated proteins that also guide other CRISPR proteins to target the invading DNA. Only a few of the CRISPR components have been characterized to date, and their mechanism of action is still largely unknown. Phage defense mechanisms probably have co-evolved against the CRISPR system, but none has yet been found. We propose to identify phage genes that counteract the CRISPR system.en_US
dc.identifier.citationMahmud Shahin, Ahmed Jahir, Aziz Md Abdul, Hasan Mirza Rokibu, Shaon Shoaib Mahmud, Bhuiyan Md Naieem Al-Hasan, Rahman Md Farzanoor, Rakib Hasibul Haque, Islam Md Shariful. Clustered regularly interspaced short palindromic repeats cas systems: a comprehensive review. International Journal of Basic & Clinical Pharmacology. 2015 Jul-Aug; 4(4): 613-622.en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/165147
dc.language.isoenen_US
dc.source.urihttps://www.ijbcp.com/?mno=191950en_US
dc.subjectClustered regularly interspaced short palindromic repeats system Plasmiden_US
dc.subjectDNAen_US
dc.subjectShort sequencesen_US
dc.titleClustered regularly interspaced short palindromic repeats cas systems: a comprehensive review.en_US
dc.typeArticleen_US
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