Single Bone Metastasis of a Squamous Cell Carcinoma of the Cervix: In the Clavicle

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Date
2025-06
Journal Title
Journal ISSN
Volume Title
Publisher
Ms. M. B. Mondal
Abstract
Cervical cancer occurs around the age of 40-45, and can be localized or metastatic. Metastatic sites vary: lymph nodes, lungs and other sites. Bone metastases are uncommon, and require histological study to confirm their secondary nature, especially in the case of unusual localizations. Case report: we report the case of a young patient followed since 2022 for a moderately differentiated, infiltrating and keratinizing squamous cell carcinoma of the uterine cervix, classified IIb, treated with concomitant radio-chemotherapy. In early 2024, a surveillance thoraco-abdomino-pelvic CT scan showed a mixed lesion of the sternal end of the left clavicle. A PET-FDG scan showed an intense, heterogeneous, hypermetabolic condensing lesion. A biopsy confirmed the diagnosis: bone localization of a moderately differentiated squamous cell carcinoma. The patient was treated with chemotherapy, followed by surgery and local radiotherapy. Conclusion: a clavicular metastasis of a cervical cancer represents a rare entity, especially in the presence of a single secondary lesion, with no other metastases elsewhere.
Description
Keywords
Clavicle, bone metastasis, single lesion, cervical cancer
Citation
Chahbounia I, Poudiougou A, Omri SE, Sella I, Antari A, Sano F, Taleb I, Traoré H, Saad MA, Slimani KA, Aalaoui L, Lamine S, Debbagh A, Khmamouche MR, Elm’hadi C, Mahfoud T, Mokhlis MA, Sbitti Y, Ichou M, Errihani H, Tanz R.. Single Bone Metastasis of a Squamous Cell Carcinoma of the Cervix: In the Clavicle . Journal of Advances in Medicine and Medical Research. 2025 Jun; 37(6): 321-326