Comparative Analysis Of Renal Parameters Test Results: Fully Automated Vs Semi Automated Biochemical Analyzer
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Date
2024-08
Journal Title
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Publisher
Indian Society for Health and Advanced Research
Abstract
Background: Clinical Biochemistry tests comprise over one third of all hospital laboratory investigations in India. Thus it's important to ensure overall quality management of the laboratory in terms of accuracy, reliability and timeline of reported test results. The present study aims to evaluate the test performance and the reliability of the results obtained by semi-auto analyzer as in comparison to fully-auto analyzer. Total 70 patients were enrolled in thisMethods: study who were advised for renal function test investigation in S.N. Medical College, Agra. The blood samples were analyzed for three biochemical parameters- Creatinine, Urea and Uric Acid on both ERBA Chem 7 (semi-auto analyzer) and Selectra Pro M (fully-auto analyzer). Statistical analysis was carried out using independent student t test, Pearson correlation, Bias percentage and Bland-Altman analysis using Microsoft Excel 2016 and Python programming language. The p-value <0.05 was considered to be statistically signicant. In our study, we found a non-signicant difference in the mean value of all theResults: three parameters- urea, creatinine and uric acid between the readings obtained on fully and semi auto analyzers while the correlative study showed signicant positive correlation for all the parameters. Bias percentage were all in acceptable range except the urea and the Bland-Altman analyses showed that the readings from both semi and fully auto analyzers were in agreement with each other. The ndings of this study suggest that the semi-auto analyzer can be used as aConclusion: reliable alternative of fully-auto analyzer.
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Keywords
Fully-auto analyzer, Semi-auto analyzer, Creatinine, Urea, Uric Acid
Citation
Goyal Akansha, Singh Kamna, Shrivastava Reetika, Gupta Arun . Comparative Analysis Of Renal Parameters Test Results: Fully Automated Vs Semi Automated Biochemical Analyzer . Global Journal For Research Analysis (GJRA). 2024 Aug; 13(8): 61-63