Evaluation of Efficacy of Levetiracetam in treating Neonatal Seizures in DHQ Hospital, Pakistan
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Date
2022-12
Journal Title
Journal ISSN
Volume Title
Publisher
IJHS Medical Association
Abstract
OBJECTIVE: evaluate the frequency of efficacy of Levetiracetam in treating seizures in neonates METHODOLOGY: In this descriptive observational study, we enrolled 110 cases from DHQ Hospital Kasur. We included all neonates of either gender, term cases, with seizures, loading dose of 50 mg/kg of intravenous levetiracetam was given at admission and maintained on a dose of 25 mg/kg every 12 hours. Outcome was measured in-terms of loss of EEG event within 72 hours of treatment and cessation of tonic, clonic seizures in ? 12hours. RESULTS: Out of 110 cases, 42.73%(n=47) were between 1-15 days of life and 57.27%(n=63) were between 16-28 days, 48.18%(n=53) were male and 51.82%(n=57) were females. The efficacy of the Levetiracetam in neonatal seizures was recorded in 62.73%(n=69) neonates. Conclusion: LEV is an effective drug for resolving neonatal seizures in our population.
Description
Keywords
Neonatal Seizures, treatment, Levetiracetam, efficacy
Citation
Umer Muhammad Waqas, Raza Hassan, Nawaz Rana Azhar . Evaluation of Efficacy of Levetiracetam in treating Neonatal Seizures in DHQ Hospital, Pakistan. IJHS Medical Association. 2022 Dec; 9(6): 1-5