A PRECLINICAL STUDY ON EVALUATION OF ANTICANCER ACTIVITY OF SNUHI KSHARA IN HUMAN COLON CANCER CELL LINE HCT-15
Loading...
Date
2023-02
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Society For Health And Advanced Research
Abstract
Snuhi (Euphorbia neriifolia Linn.) is a conventional herb used broadly in several disease conditions as indicated in classical texts of Ayurveda. As per literature review ascertained, no literature was accessible regarding anticancer activity of Snuhi Kshara. Thus, present work was designed to evaluate the anticancer activity of Snuhi Kshara in HCT-15 (Human Colon Cancer cell line). Anticancer activity was evaluated using MTT assay by % cell viability and IC50. Anticancer activity was compared with standard drug capecitabine. A positive correlation between Concentration and % cell viability was noticed. Lowest cell viability was noted at 5000 µg concentration. Results obtained through the study indicates towards anticancer activity of Snuhi Kshara.
Description
Keywords
Ayurveda Agadtantra, Snuhi (Euphorbia neriifolia Linn.), Snuhi Kshara (SK), Anticancer, In Vitro, MTT assay, % cell viability, IC .
Citation
Govindrao Asolkar Geeta, Vithalrao Nikam Ashwin, Venkatrao Pawade Uday, Pramodrao Anjankar Meghsham. A PRECLINICAL STUDY ON EVALUATION OF ANTICANCER ACTIVITY OF SNUHI KSHARA IN HUMAN COLON CANCER CELL LINE HCT-15. Indian Journal Of Applied Research. 2023 Feb; 13(2): 33-35