Activity of Autonomic Nervous System, Energy Expenditure and Assessment of Oxidative Stress in Menopause-women Using Hormone Replacement Therapy.
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Date
2015
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Abstract
Aims: Menopause is a period of significant physiological change that may be associated with increased body weight and obesity-related diseases. Many studies have been carried out to determine influences of estrogen depletion, resting energy expenditure (REE) decline and aging during menopause-related obesity.
Methodology: In the present experiment, REE, body composition, activity of the autonomic nervous system, oxidative stress and food intake were measured in three groups of women: pre-menopause (n=40), post-menopause with hormone-replacement therapy (HRT) (n=40) and post-menopause without HRT (n=40).
Results: In post-menopause women with HRT a significant increase was found in: 1) the sympathetic activity, measured by the power spectral analysis of the heart rate variability; 2) REE, measured by indirect calorimetry; 3) oxidative stress, measured by Free Radical Analytical System 4 (Fras-4) compared to the value of the other two, while fat mass, measured by Body Impedance Analysis (BIA), was reduced in favor of a recovery of free fat mass.
Conclusion: The study emphasizes the important changes due to HRT on various components influencing body weight in menopause-women.
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Keywords
Hormone-replacement therapy, resting energy expenditure, autonomic nervous system, body composition, assessment of oxidative stress
Citation
Messina Giovanni, Luca Vincenzo De, Viggiano Andrea, Tafuri Domenico, Messina Antonietta, Moscatelli Fiorenzo, Triggiani Antonio Ivano, Cibelli Giuseppe, Valenzano Anna, Chieffi Sergio, Monda Marcellino. Activity of Autonomic Nervous System, Energy Expenditure and Assessment of Oxidative Stress in Menopause-women Using Hormone Replacement Therapy. British Journal of Medicine and Medical Research. 2015; 10(8): 1-13.