Please use this identifier to cite or link to this item: https://imsear.searo.who.int/handle/123456789/179412
Title: Prophylactic Intramuscular PGF2  Versus Intravenous Methylergometrine For Prevention Of Atonic PPH In High Risk Pregnant Women.
Authors: Qayoom, Shazia
Khajuria, Reema
Mahajan, Sudhaa
Keywords: Prophylactic PGF2
Prophylactic Methylergometrine
High Risk Women
Atonic PPH
Issue Date: Apr-2016
Citation: Shazia Qayoom, Reema Khajuria, Sudhaa Mahajan. Prophylactic Intramuscular PGF2  Versus Intravenous Methylergometrine For Prevention Of Atonic PPH In High Risk Pregnant Women. JK Science Journal of Medical Education and Research. 2016 Apr-Jun;18(2): 107-110.
Abstract: To assess, evaluate and compare the safety and efficacy of i/m PGF2  125 mcg and i/v methylergometrine 0.2 mg during active management of third stage of labor in high risk pregnant women who are prone to develop atonic postpartum hemorrhage. The study was conducted on two hundred women prone to develop PPH with vertex presentation and spontaneous onset of labor at term. Slected cases were divided into two groups: Group I – Comprised of 100 women who were given 125 microgram of intramuscular 15 methyl PGF2  (Carboprost) at the time of delivery of anterior shoulder prophylactically. Group II – Comprised of 100 women who were given 0.2 milligrams of intravenous methylergometrine, at the time of delivery of anterior shoulder prophylactic ally. Tools of statistical analysis used were paired ‘t’ test , ‘Z’ test and mean ± SD. The mean duration of the third stage of labor after giving uterotonic drug was significantly shorter in Group I (3.50 ± 1.10 mins) as compared to Group II (5.15 ± 1.30 min) (p<0.001).The mean blood loss was significantly less in Group I (85 ± 30 ml) versus Group II (185 ± 40 ml) (p<0.0001).There was no statistical difference in mean haemoglobin concentration observed before and 48 hrs after delivery. The only significant side effect was diarrhoea in Group I. Prophylactic intramuscular PGF2  125 mcg is a better alternative to prophylactic intravenous methylergometrine 0.2 mg in high risk pregnant women who are prone to develop atonic PPH.
URI: http://imsear.searo.who.int/handle/123456789/179412
Appears in Collections:JK Science Journal of Medical Education and Research

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