Acinetobacter Species Associated with Spontaneous Preterm Birth and Histological Chorioamnionitis.
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Date
2014-11-21
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Abstract
Aim: Preterm birth is a complex and unresolved public health problem across the globe.
Infection is a factor for which a causal link has been established with preterm birth. A
better understanding of its aetiology is required to improve obstetric and neonatal care.
The case highlights the limitations of current obstetric hospital microbiology tests, and
contributes to the knowledge of bacterial pathogens in the female genital tract associated
with preterm birth.
Case Presentation: A woman presented with no signs of infection and spontaneously
delivered preterm at 34 weeks gestation. Culture-based microbiological results from
blood samples and swabs of mother and child were negative. Postpartum histopathology
of the placenta demonstrated chorioamnionitis, and vasculitis of the umbilical cord.
Cultivation-independent PCR analyses showed a massive Acinetobacter spp. infection.
Conclusion: Cultivation-independent PCR analyses may detect potentially pathogenic
species when standard culture-based techniques are negative. The frequency of Acinetobacter spp. infections during pregnancy and in neonatal units manifests the need
to develop appropriate diagnostic methods that can become standard practice in
hospitals and clinics.
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Keywords
Acinetobacter, infection, pregnancy, preterm birth
Citation
Quinlivan Julie A ,Kaakoush Nadeem O, Mendz George L. Acinetobacter Species Associated with Spontaneous Preterm Birth and Histological Chorioamnionitis.British Journal of Medicine and Medical Research. 2014 Nov; 4(33): 5293-5297.