Serum High Sensitive C - reactive protein in Male Smokers of Bangladesh.
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Date
2015-06
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Abstract
Background: Smoking may cause systemic inflammation, and high level of serum high sensitive Creactive
protein may be found in smoker as an indicator of inflammation. Objective: To assess the
serum high sensitive C - reactive protein level in male smokers of Bangladesh. Methods: The present
cross sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka
between July 2013 and June 2014. Hundred apparently healthy male regular cigarette smokers aged 20
to 40 years who smokes at least 5 sticks of cigarette per day for the last 5 years were included as study
group. They were further divided in to 5-10 years, 11-15 years, 16-20 years and 1-10 cigarette sticks, 11-
20 cigarette sticks, more than 20 cigarette sticks/day depending on the duration of smoking and also
according to consumption of number of sticks/day respectively. Age matched 100 apparently healthy
male nonsmokers were included for control. To assess their inflammatory status, serum hs-CRP level
was estimated by particles enhanced immunonephelometry using BN Systems in the Department of
Microbiology & Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. In
addition, BMI and blood pressure were measured by standard method to observe their association
with smoking. Results: The mean serum hs-CRP level was significantly higher in male smokers than
that of non smokers which was progressively increased with duration of smoking and number of
cigarette sticks consumed per day. Again, mean BMI was significantly lower and diastolic blood
pressure was significantly higher in male smokers than those of non smokers. Conclusion: The result
of this study can be concluded that serum hs-CRP level progressively increases with duration of
smoking and number of cigarette sticks consumed per day in male smokers.
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Keywords
Serum hs-CRP, BMI, Blood pressure, male smoker
Citation
Jahan Shamima, Akhter Qaz Shamima. Serum High Sensitive C - reactive protein in Male Smokers of Bangladesh. Journal of Bangladesh Society of Physiologists. 2015 June; 10(1): 36-40.