Fasting Insulin in Essential Hypertension.
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Date
2014-12
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Abstract
Background: An association between essential hypertension and defective insulin secretion has
been identified. Objective: To estimate fasting serum insulin level in adult male with essential
hypertension to observe its relationship to hypertension. Methods: This cross sectional study was
conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2012 to June
2013. A total number of one hundred fifty male subjects were selected with age ranging from 25 to 45
years. Seventy five male essential hypertensive were enrolled from Out- patient Department of Medicine,
Dhaka Medical College Hospital, Dhaka. Age matched seventy five apparently healthy males were
studied as control. Fasting serum insulin level was measured by ELISA method and fasting blood
glucose by glucose oxidase method. For statistical analyses, unpaired Student’s ‘t’ and Pearson’s
correlation coefficient (r) tests were performed. Results: Fasting serum insulin level was significantly
(P<0.001) higher in essential hypertensive male patients than normotensive subjects. Fasting serum
insulin level shows significant positive correlation with systolic blood pressure in hypertensive
patients. Conclusion: This study reveals that essential hypertension has positive and significant
relationship with fasting serum insulin level.
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Keywords
Essential hypertension, fasting serum insulin level, systolic blood pressure
Citation
Sinha Susmita, Akhter Qazi Shamima, Akhter Qazi Farzana, Tasnim Masuma, Rahman Farhana. Fasting Insulin in Essential Hypertension. Journal of Bangladesh Society of Physiologists. 2014 Dec; 9(2): 54-58.