Antibacterial Activity of Essential Oil of Syzygium Aromaticum (L.) Merr.Perry (Cloves) Against Clinical Isolates of Aggregatibacter Actinomycetemcomitans.
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Date
2015-04
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Abstract
Aim: Aggregatibacter actinomycetemcomitans implicated in the etiology of aggressive, chronic
periodontitis and other systemic infections. The aim of this study was to investigate the antibacterial efficacy of
essential oil of a traditional medicinal plant, Syzygium aromaticum (L.) Merr.perry (cloves) against the clinical isolates
of A.actinomycetemcomitans obtained from the patients with orodental infections. Methodology: Essential oil of clove
flower buds was distilled by Neo-Clevenger’s method and the antibacterial activity was tested by disc diffusion and agar
punch well method. The minimum inhibitory concentration of clove oil was determined by micro broth dilution method.
Results: 80.8% of the isolates showed sensitivity against clove oil by disc diffusion technique and the minimum
inhibitory concentration of clove oil was ranged between 3.125μl/ml to 12.5μl/ml. Conclusion: Essential oil of
Syzygium aromaticum showed good antibacterial activity and can be considered as alternative treatment option for
control of periodontitis and other orodental infections caused by A.actinomycetemcomitans.
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Aggregatibacter actinomycetemcomitans, Syzygium aromaticum, Essential oil of clove, Minimum Inhibitory Concentration
Citation
Karicheri Ramanath, Antony Beena. Antibacterial Activity of Essential Oil of Syzygium Aromaticum (L.) Merr.Perry (Cloves) Against Clinical Isolates of Aggregatibacter Actinomycetemcomitans. International Journal of Applied Biology and Pharmaceutical Technology. 2015 Apr-June; 6(2): 157-162.