Extra Pontine Myelinolysis without Striatal involvement Presenting as Pathological Crying, Reversible Parkinsonism and Dystonia.
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Date
2007-10
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Abstract
A case of Central Pontine Myelinolysis and Extrapontine Myelinolysis presented with
dystonia, Parkinsonism, and pathological crying that developed few days after gradual
correction of hyponatremia. EEG slowing was evident before onset of symptoms, and
disappeared with clinical improvement. Thalamic lesions alone produced these features.
It dramatically responded to the Trihexyphenidyl therapy. Thus, basal ganglia involvement
is not mandatory to produce this clinical picture; early onset of symptoms, resolution of
EEG slowing and prompt response to anticholinergics may indicate better prognosis.
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Keywords
Exrapontine Myelinolysis, Pathological Crying, Parkinsonism, Dystonia
Citation
Gupta Ravi, Goel Deepak, Sangal Ankur, Kukreti Ranjan, Singhal Anil. Extra Pontine Myelinolysis without Striatal involvement Presenting as Pathological Crying, Reversible Parkinsonism and Dystonia. Delhi Psychiatry Journal. 2007 Oct; 10 (2): 150-153.