Acute psychosis induced by topiramate.
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Date
2014-03
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Abstract
Topiramate (TPM) is a new potent antiepileptic drug (AED) used as add-on therapy
for generalized and partial seizures that are resistant to the other AEDs; or as a mood
stabilizer, and for reducing weight gain associated with olanzapine and clozapine in
patients with bipolar disorder or schizophrenia. However, there is a higher risk of
psychosis with TPM in patients with a past history of psychiatric disorder. This case
report highlights emergence of psychosis that was related to TPM which resolved
on discontinuation.
Description
Keywords
Topiramate, Mania Rating Scale, Brief Psychiatric Rating Scale, Drug–drug interaction, CYP450
Citation
Raj Rajnish, Kumar Raj. Acute psychosis induced by topiramate. International Journal of Basic & Clinical Pharmacology. 2014 Mar-Apr; 3(2): 405-407.