Transdermal drug delivery system: A review.
Loading...
Date
2013-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Delivery of drugs through the skin has been always a challenging area for research due to barrier properties exhibit by the outermost layer of skin
stratum corneum. In the last two decades, the transdermal drug delivery system has become a proven technology that offers significant clinical benefits over other
dosage forms. Because transdermal drug delivery offers controlled as well as predetermined rate of release of the drug into the patient, it able to maintain steady
state blood concentration. It’s a desirable form of drug delivery because of the obvious advantages e.g.convenient and pain-free self-administration for patients,
avoidance of hepatic first-pass metabolism and the GI tract for poorly bioavailable drugs over other routes of delivery. The outlook for continued growth of the
TDD market is very optimistic.Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an
alternative to oral delivery and hypodermic injections. This review emphasizes the three generations of transdermal drug delivery which start a new era of delivery
of drug.
Description
Keywords
Barrier, TDD, first pass metabolism
Citation
Sachan Richa, Bajpai Meenakshi. Transdermal drug delivery system: A review. International Journal of Research and Development in Pharmacy and Life Sciences. 2013-14 Dec-Jan; 3(1): 748-765.