International Journal of Ayurveda and Pharma Research

Editor in Chief: Dr. B. Srinivasulu

ISSN: ISSN : 2322-0910 (Online) 2322-0902 (Print)

Frequency: 6 issues a year

Language: English

Online peer reviewed journal

Web site: https://ijapr.in/

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Now showing 1 - 20 of 891
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    Management of Hridroga (CVD’S)
    (Mahadev Publications, 2024-04) Pagadala, Manvitha; Maharjan, Bikash
    Hridraya is an epitome of sustenance and co-ordination to maintain Ayu. It is considered as one of the three Marma sthana, and is the seat of Sarira, Buddhi, Indriya, Indriyartha, Saguna atma, Mana, etc so, any deviation in its functioning can be tremendously bereaving. Acharya Charaka, Sushruta, Vagbhata and Bhela have been unanimous regarding Hridaya being the seat of Manas and Buddhi. Hridroga is an ocean full of disease entities. In contemporary medical system, it is known as CVD i.e., Cardio-Vascular Disease. CVDs are the leading cause of death taking an estimated 17.9 million lives in 2019 accounting for whooping 32% of all the global deaths. Most cardiovascular diseases can be prevented by addressing behavioural risk factors such as tobacco use, unhealthy diet and obesity, physical inactivity and harmful use of alcohol. These risk factors can be effectively tackled by the judicious adherence to Dinacharya, Ratricharya, Ritucharya, Sadvritta niyamas, etc. Even in the state of disease, compliance with Sodhana procedures and Oushadhas can lead to alleviation of disease and qualitative improvement in the state of Ayu. This article gives 360° view of Shaman oushadhas related to Hridroga, which is explained by the Apta in various ancient texts.
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    A Conceptual Review of Allergic Rhinitis According to Ayurveda
    (Mahadev Publications, 2024-04) Yadav, Sarita; Alka; Gupta, Sangeeta; Patra, Anupama
    The study focuses on the global health concern of allergic rhinitis, a condition that affects approximately 400 million people worldwide. The prevalence of allergic rhinitis characterized by recurrent attacks of sneezing, nasal congestion and rhinorrhoea has increased over the years due to urbanization and environmental pollution. Although modern medicine has developed treatments for allergic rhinitis, it is still incurable. In Ayurveda, there is a concept of Sannipatik disorders, which involves the vitiation of all the three Doshas (Vata, Pitta, and Kapha) in the pathophysiology of the disease. Sannipatik diseases are known to be particularly challenging to treat. The symptoms of allergic rhinitis closely resemble the diseased condition called Sannipatik Pratishayaya in Ayurveda. While modern medicine offers anti-allergic, antihistaminic, corticosteroids, and other treatment options, these are not entirely effective in curing the disease or preventing its recurrence. Additionally, these treatments often come with their own side effects. In contrast, Ayurvedic classical texts provide detailed explanation of the pathophysiology, sign and symptoms and principles of treatment for effective management for Sannipatik Pratishayaya. Thus, the Ayurvedic concept of Sannipatik Pratishyaya and its understanding can be helpful in managing allergic rhinitis. Aim- The aim of the article is to correlate symptomatology of Sannipatik Pratishyaya with allergic rhinitis and discuss the role of various treatment modalities according to Ayurveda. Methods- Literary review of various Ayurvedic texts, electronic databases; online Journals in the field available at various search portals. Result-The final outcome of the study is to find out a permanent treatment measure for this problem that can be further tested by practical application.
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    Management of Rigidity Dominant Parkinson’s Disease Through Ayurvedic Protocol
    (Mahadev Publications, 2024-04) Jose, Jesny V; Shylamma, T M; V K, Aparna
    Parkinson's Disease (PD) is a disease with insidious onset and slow progression. It is a neurologic condition that causes motor manifestations namely, bradykinesia, rigidity, resting tremor, postural instability and non-motor symptoms such as depression and dementia. The modern treatment provides some symptomatic relief but any proven means for slowing the progression have not been found yet. This case is of a 64-year-old male patient who presented with complaints of slowness in daily activities, difficulty in raising left upper arm along with heaviness, tremors in both hands, difficulty in speech and movement for 3 years. Complaints were increasing progressively hindering his routine activities. He underwent our IP management for 60 days with follow-up after every 20 days. In every follow-up, the patient reported significant relief in his symptoms and after two months, he was able to perform his routine activities without any help.
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    Chronic Kidney Disease in Light of Ayurveda: A Literary Review on Vataj Pandu
    (Mahadev Publications, 2024-04) Mishra, Swati; Dash, Rashmisnata; Sapna; Kumar, Sujeet
    In recent years, chronic kidney disease (CKD) has become a centre of attraction for researchers all over the world, due to increasing incidence. However, delayed diagnosis and lack of proper management has made it one of the leading causes of death worldwide. In the earlier phase of the disease, relief to the patients can be provided based on chief complaints. But as the disease progresses, only dialysis and kidney transplants remain the line of treatment according to the mainstream system of medicine, thus leading to a large number of side effects and ultimately decreasing the life expectancy. In Ayurveda, CKD is not mentioned in the Samhita directly, but it can be correlated with Vataj pandu according to similarities in some of the symptoms and causes of these two diseases as mentioned in ancient literature. We can also look out for the Nidaan and Samprapti according to the history given by the patient and evaluate the Dosh, Dushya, and the Srotas involved, and then devise a line of treatment according to the patient's Bala, Prakriti, Agni and Oja. In this article, we're going to talk about an aspect of CKD that can be used as a part of management to improve the quality of life and give hope to all the patients suffering from this disease.
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    Ayurvedic Management of Vulvovaginal Candidiasis with Local Application of Guduchi-Triphala-Danti Gel
    (Mahadev Publications, 2024-04) B S, Chindu; Balakrishnan, Maya; Thomas, Giby
    Vulvovaginal candidiasis is the infection of the vaginal mucosa and/or vulva caused by the Candida species, a gram-positive yeast-like fungus. It is the second most common vulvovaginal infection characterized by thick-curdy white-cottage-cheese type vaginal discharge and intense vulvovaginal pruritus. Symptomatically vulvovaginal candidiasis can be compared with Slaishmiki yonivyapat in Ayurveda, the line of management of which is the use of Ruksha and Ushna aushadha. Local application of gel has the advantages of easy administration, more bioavailability of drugs, and prolonged retention without much local irritation. The classical Guduchi-Triphala-Danti pariseka yoga, mentioned in Yonivyapat chikitsa has been modified into a gel form, facilitating self-administration by women. Methodology: Here is a case report of a 31-year-old multiparous woman who presented with complaints of curdy white vaginal discharge associated with itching over the vulvar region for the last 6 months. She was diagnosed with vulvovaginal candidiasis by vaginal swab culture. Intervention with Guduchi-Triphala-Danti gel was carried out for 14 days for 2 consecutive cycles excluding days of menstruation and followed up after the next 30 days without medication. Results: After completion of the treatment protocol there was substantial relief of symptoms like curdy white vaginal discharge and itching over the vulvar region, wet-mount microscopy was negative for pseudohyphae, and the vaginal swab culture showed no growth. Conclusion: Local application of Guduchi-Triphala-Danti gel was found to be effective in the management of vulvovaginal candidiasis.
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    An Approach to the Management of Dizziness (Murcha) and Vertigo (Bhrama) Based on Ayurvedic Classics
    (Mahadev Publications, 2024-04) Sapna; Mishra, Swati; Dash, Rashmisnata; Kumar, Sujeet
    Ayurveda is a science of life as it defines health and factors responsible for its maintenance and promotion. It is one of the oldest traditional systems of medicine which comprises of thousands of concepts and hypothesis. The primary objective of Ayurveda includes maintenance of health and prevention of diseases. At present, dizziness and vertigo are common symptoms in the patients with the rising prevalence of about 20%. Dizziness is correlated with Murcha in Ayurveda, which is a general feeling of being unstable and fainting whereas vertigo is correlated with Bhrama which is illusion of self and environmental motion. Modern medicines nowadays have harmful impact on health due to their side effects that affect the quality of life. So this is the need of the time that a direct, safe and holistic approach should be established to treat the diseases. The fundamental principles hold a strong ground in Ayurveda. Our Ayurveda classics have mentioned a lot about signs and symptoms of various diseases with their specific herbs. Ayurveda drugs popularity and demand are increasing day by day. Ayurveda drugs are helpful in treating the dizziness (Murcha) and vertigo (Bhrama) through the principles of nature to bring back the individual into equilibrium.
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    Management of Dushta Vrana with an Ethnomedicine Theepana (Allophylus Cobbe (L.) Raeuch Leaves Choorna
    (Mahadev Publications, 2024-04) Jain, Payal; Avalaskar, Amit
    “Ethno” (derived from “ethnic”) is a custom of a particular race or religion and ethnomedicine is a custom of medicine. The discovery of new crude drugs from indigenous reported medicinal plants can be done from ethnomedicinal studies. There is a persistent increasing demand of medicines in the market which makes them costlier. Because of which the use of other substitutes and adulterants is increasing; questioning the efficacy of the actual medicine. Theepana could help to overcome the cost and adulteration of other Vranaropan medicines like Arjun. It is from Sapindaceous family; (soapberry family). Genus is Allophylus. Sanskrit name- Triputa (only according to some viewers. No textual reference available for Triputa as Sanskrit name). Marathi name- Theepana, Thivana, Tipin. Theepana (Allophylus cobbe (L.) Raeuch” leaves Choorna was used as an ethnomedicine in Dushta vrana. The leaves Choorna shows Shothagna (anti-inflammatory), Krimigna (antimicrobial), Vranashodhana and Vrana ropan effects. Dushta vrana (chronic ulcer), manifested in any part of the body, may be caused either by the Doshas or trauma. When caused due to the Doshas, it is called Nija vrana and when caused because of trauma; it is called Aagantuja vrana. According to Madhav Nidan-Vrana having Durgandhit - more Gandha, Vedana, Puyayukta Strava, Chirsthithi and Strava, Varna is known as Dushta Vrana.
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    A Case Study on the Ayurvedic Approach to Managing Psoriasis (Ek Kustha)
    (Mahadev Publications, 2024-04) Bagwari, Mohit; Agrawal, Atul Kumar
    Ek-Kushta is similar to psoriasis. In the present era, this disease remains a matter of serious concern. These symptoms can be compared to Ek-Kushta. The digestive fire Agni also get Manda consuming red meat, non-veg food and drinks are more prone to get skin diseases like psoriasis or many auto immune disorders. The skin disease was referenced in the Kushta chapter of Charaka Samhita, along with other Samhitas, in our classical texts. For this many different Chikitsas like Shodana shaman, Virechana etc are explained in our classics. Here, a traditional Ayurvedic regimen was attempted to treat a 20 year old male. Methods: Samshodhana with Samshamana medication are the treatment for all varieties of Kushta. In this study, Virechana was administered first, followed by Samshamana medicine. Results: The evaluation of signs and symptoms was conducted prior to the commencement of treatment and subsequently after the completion of treatment. Following 4 weeks of scaling treatment, there was a reduction in the thickness of the skin, which had a sharply defined margin, was indurated, and presented as an erythematous plaque on the scalp, face, chest, abdomen, whole back, upper and lower limbs. Significant improvement in psychological and social behavior, which improved the quality of life of patients. After 4 weeks of treatment, the results of the Positive Auspitz's and candle grease sign were found to be negative. Conclusion: Virechana and Samshamana is effective in the management of Ek-Kushta (Psoriasis). After 4 weeks of observation, it appears Virechana and Samshamana can be used to decrease disease progression.
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    A Single Centric, Open-Label, Non-Randomized Post- Marketing Surveillance Study to Measure the Efficacy and Safety of Petsaffa Tablets in Subjects Suffering From Constipation, Gas and Acidity
    (Mahadev Publications, 2024-04) Verma, Shreya; Verma, Amrish; Singh, Jaspal; Ahmed, Hasan Ali; Kadam, Dilip
    Constipation, gas, and acidity are common gastrointestinal issues with a significant global prevalence. Traditional medicine systems like Ayurveda have long utilized medicinal plants to address these concerns. However, clinical validation of their efficacy in patients with constipation has been lacking. Objectives: This study aimed to assess the efficacy and safety of Petsaffa tablets, an Ayurvedic formulation containing various herbal ingredients, in relieving constipation, gas, and acidity. Methods: The study, conducted as a single-centric, open-label, non-randomized post-marketing surveillance study, involved 120 subjects with constipation. Subjects were evaluated using inclusion and exclusion criteria and provided Petsaffa tablets for a 14-day intervention. Various parameters, including bowel movement frequency, constipation scores, and subjective assessments, were measured. Vital signs, laboratory safety parameters, and adverse events were also monitored during the study period. Results: Petsaffa tablets significantly improved bowel movement frequency, constipation scores, and subjective symptoms related to constipation. Stool consistency and other associated symptoms such as acidity and gas were also reduced at the end of the study. None of the participants reported any adverse events, and safety parameters remained within normal limits during the study period. Conclusion: Petsaffa tablets offer a promising, safe, and effective alternative option for individuals with common gastrointestinal issues such as constipation, acidity, and gas.
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    Management of Ahiputana (Diaper Rash) though Triphala Khadir Yog (TKY) Avachoornan
    (Mahadev Publications, 2024-04) Gaikwad, Jyoti Vijay; Chaudhari, Vivek Murlidhar
    Ayurveda is an ancient medical system that addresses both the state of Swasthya, or optimal human health, and a broad range of illnesses and associated therapies. One of the most frequent issues in pediatric OPD is diaper rash. According to Ashang Hridaya, Maloplep (contained faeces) and Sweda (sweat/perspiration) both causes Kandu (irritability), Daha (burning sensation) and Tamra Varna (redness), Strava (discharge), Vrana (wound formation around the perianal region), Pidika (papulovesicular lesion) around the Guda area (napkin area). In Ahiputana there is Pitta, Kapha and Rakta Dosha Prakop (increase). In present case report, a 11-month-old female baby patient presented in Balrog OPD 13 of Sane Guruji Rugnalaya, Hadapsar, Pune, with complaints of loose motion episodes, itching and redness associated with discharge and burning sensation for 3 days and was treated with external application of Triphala Khadir Yoga. After complete treatment of 10 days, there was complete remission in the symptoms and there is no recurrence till date. From the current case report, it can be inferred that Ahiputana (diaper rash) can be successfully treated with the appropriate Ayurveda medications.
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    Silajathu Rasayana in Management of Rheumatoid Arthritis
    (Mahadev Publications, 2024-04) N, Nanditha; Giri, P V
    Rheumatoid Arthritis is a systemic autoimmune disease characterized by inflammatory arthritis and extra-articular involvement. Considering the pathophysiology, clinical features, and extra-articular manifestations it can be correlated to Vataraktha in Ayurveda. In this case, a 24-year-old female patient who was diagnosed with Juvenile Rheumatoid Arthritis at the age of 15 and was under Disease-modifying anti-rheumatic drug therapy for several years, complaints of pain and swelling over symmetrical joints of upper and lower limbs along with morning stiffness, and evident boutonniere deformity. She also had pain in her left hip for 4 years. Ayurvedic treatment was initiated with a primary focus on Amapachana, Shodhana, and Rasayana therapies. Patient assessment was conducted using a Visual analog scale, DAS28 score, HAQ-DI score, and Ama assessment tool on the 0th and 69th day. DAS 28 score improved from 7.73 to 3.19, and HAQ-DI score improved from 1.63 to 0.88. The visual analog scale was improved from 8 to 4. Following 69 days of treatment incorporated with Ayurvedic treatment procedures coupled with Rasayana therapy, demonstrated a notable amelioration of symptoms, an enhancement in the overall quality of life, and an improvement in laboratory parameters.
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    Effect of Mudgadi Kashaya Peya and Selected Yoga Techniques in Overweight
    (Mahadev Publications, 2024-01) Ravi, Arjun; A, Nafeesath Beevi; R, Jyothi.
    Overweight is defined as abnormal or excessive fat accumulation that presents a risk to health. Once considered a problem only in high-income countries, overweight and obesity are now dramatically on the rise in low and middle-income countries, particularly in urban settings. Overweight and obesity are the fifth greatest risk factors for death worldwide. Due to secondary consequences including obesity, type-2 diabetes mellitus, coronary heart disease, dyslipidemia, etc., the morbidity and mortality of overweight people are rising. Obesity and overweight are primarily caused by an imbalance in energy between calories consumed and calories burned. To maintain balance between the two, the management approach attempts to reduce energy intake while boosting energy expenditure. In Ayurveda, overweight can be correlated to Sthoulya. In this study an intervention along with addition of one dietary intervention was made into the daily routine of subjects. Here yoga is most suitable adaptation of physical activity and Mudgadi kashaya peya is a dietary preparation having Kapha medohara property which can reduce the over gaining weight and presence health.
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    A Comparative Phytochemical Analysis and HPTLC Fingerprinting of Ardraka and Shunti in Different Dosage Forms and its Relation to Diabetes
    (Mahadev Publications, 2024-04) Vrinda; H S, Supriya; Bhat, Sulochana
    Ginger is a household spice used globally for different purposes. As per Ayurveda, it is considered to possess therapeutic properties for various ailments. Although ginger has Pramehagna (anti-diabetic) property, there are very few formulations for diabetes that contain this as an ingredient. However, some pharmaceutical and clinical studies have shown significant anti-diabetic property of ginger. According to Ayurveda, Ardraka (fresh rhizome) and Shunti (dry rhizome) have different properties and are widely used in many formulations. To analyze the difference between both forms of ginger in varied forms, phytochemical screening, and HPTLC study was done on Ardraka swarasa (juice of fresh rhizome), Shunti churna (powder), Ardraka and Shunti Kashaya (decoction of fresh and dry ginger), Ardraka and Shunti Hima (cold infusion of fresh and dry ginger), Ardraka and Shunti phanta (cold decoction of fresh and dry ginger). Alkaloids were present abundantly in Ardraka swarasa, Ardraka kashaya, Shunti kashaya, Shunti hima and Shunti phanta. Flavonoids were present in excess only in Ardraka swarasa. HPTLC analysis showed more peaks in Kashaya of both forms of rhizomes and Ardraka phanta.
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    Effect of Intravaginal Application of Palasha Udumbaradi Ointment on Pelvic Organ Prolapse
    (Mahadev Publications, 2024-04) Krishna, K. O; Balakrishnan, Maya; Thomas, Giby
    Prolapse is a downward descent of the female pelvic organs as a result of weakness of the structures that normally retain them in position. The main symptoms of pelvic organ prolapse include micturition disturbances like stress incontinence, imperfect control of micturition, a feeling of lump coming down, postural low back ache, constipation and leucorrhoea. The management of pelvic organ prolapse includes preventive conservative and surgical measures. Surgery is indicated when conservative management fails. The three different conditions like Phalini, Prasramsini and Mahayoni vyapath mentioned by different Acharyas explain the prolapsed condition according to the stage and part prolapsed out. Palasha udumbaradi yoga mentioned in Bhaishajya Ratnavali containing ingredients such as Palasha beeja, Udumbara phala, Thilathaila and Madhu was taken for this study. The Lepa was applied in the modified form of an ointment. The study is an attempt to assess the effect of Palasha udumbaradi ointment on uterine prolapse. The ointment was applied intra vaginally. The presence of dense blood vasculature makes the vagina a potential site for local and systemic drug administration. The key advantages of vaginal drug delivery over oral administration is that this is able to circumvent the harsh gastric environment and also bypass hepatic first-pass metabolism. A 38 year woman with complaints of increased frequency of micturition, stress incontinence, burning micturition, low back ache and dyspareunia consulted the OPD of Govt. Ayurveda Medical College, Tripunithura. Palasha udumbaradi ointment was self-applied intra-vaginally. Administration of ointment was advised for 60 consecutive days excluding the days of menstruation with follow up on 90th day. Assessment was done on 0th, 30th and 60th day and follow up was done on 90th day using POP-Q Scale, urinary incontinence scale, and visual analogue scale.
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    Elevating the Inner-Consciousness “Third-Eye” Through “Vedic Manas Yoga” Practice
    (Mahadev Publications, 2024-04) Balkrishna, Acharya; Katiyar, Prashant; Chauhan, Muskan; Upreti, Jaya; Srivastava, Shubhangi; Aggrawal, Upasana; Singh, Shalini; Arya, Vedpriya
    ‘Third-Eye Chakra’, also known as ‘Ajna Chakra’ in Sanskrit, is the sixth of the body's seven major Chakras. It is also known as the "perception center" and, said to be the seat of soul and the portal to higher awareness. It is essential for achieving greater awareness and serves as the focus of concentration during Asana or meditation practices. Ajna Chakra corresponds to the hypothalamus, pituitary gland, and pineal gland, as well as the eyes, ears, and nose in the physical body. Vedic manas yoga is a holistic approach to yoga that integrates concepts from the Vedas, ancient Indian literature, with practices that attempt to balance the mind, body, and spirit. This study was conducted to develop the inner consciousness and awake the dormant powers of individual participants using Vedic manas yoga. In this observational study, a total 30 physically and mentally healthy subject aged in between 5 to 15 years of both gender from Patanjali Gurukulam, Haridwar, were included. The Pre- and Post-treatment SF-36 scores were statistically evaluated using paired t-test. There was a significant difference (p<0.5) observed in mean scores of Pre-program and Post-program scores of SF-36 after three days programmed interventions against psycho-social, spiritual and emotional development of subjects. The paired t-test revealed a significant score having p<0.05 for pre-program and post-program questionnaire responses. The maximum improvement was recorded to be 22% with overall third-eye activation. Vedic manas yoga practice has shown significant improvement in SF-36 among subjects participating in this study and, further studies are recommended to awaken the inner consciousness and align the energies of body, mind and spirit.
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    Review on the Effect of An Ayurvedic Management Protocol in Chronic Obstructive Pulmonary Disease
    (Mahadev Publications, 2024-03) Aswathy, M; M, Jithesh
    Considering the similarities noticed in the etiology and clinical features, COPD can be correlated to Tamaka shvasa among the Pranavaha srotodushti vikara, a condition where Pitta is involved along with Kapha and Vata. Rasayana is the main intervention in such a chronic disease and considering the Doshas and Rasayana, Virecana is the best preparatory Shodhana here to be administered for the patients. In Ayurveda, drug is denoted by the term ‘Bheshaja’ which is defined as the substance through which we can overcome the fear of disease. The ‘Upakarana’ which helps physician for maintaining the healthy condition or to alleviate disorders is said to be Bheshaja. Physician accomplishes the object ‘Vikara shamana’, by giving the appropriate Bheshaja according to different stages and conditions of the patient and disease. According to Ayurveda, action of a drug is based on its Guna, Virya, Vipaka and Prabhava. Fate of the drug always depends on Rasapancaka and it goes in line with modern pharmacodynamics. Besides that, the drug action also depends on the action of agni on that particular drug. In this article, a management protocol review on Chronic Obstructive Pulmonary Disease was carried out. The protocol selected and reviewed was Dipana with Panchakola curna in hot water, Snehapana with Kantakari ghrta, Abhyanga with Tila taila followed by Ushmasveda, Virecana with Vidangatanduladi curna and finally Pippali Vardhamana rasayana.
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    Severe Clinical Insomnia Management with Ayurvedic Protocol - A Case Report
    (Mahadev Publications, 2024-03) Thengil, Shilpa; Krishna, Ambili
    Insomnia is characterized by inability to sleep or lack of sleep. Severe clinical insomnia is a highly prevalent health concern faced by a wide majority of people across the globe due to the rise in stressful external environments. Often such cases require long term use of sedative hypnotics or tranquilizers which are habit forming. Ayurveda identifies insomnia as Nidranasa and is a disease which is caused predominantly by Vata Pitta increase and a dip in Kapha levels. Ayurvedic treatment protocol involves internal medication and topical procedures like Shirodhara and Abhyanga. This case report is intended to throw light to a positive outcome of Ayurvedic treatment protocol in severe clinical insomnia. A 34-year-old male presented with symptoms of severe clinical insomnia assessed by Insomnia Severity Index (ISI) associated with obesity and had a history of consuming hypnotics. The treatment protocol included Dhanyamladhara, Udvartana, Takradhara, Abhyanga and Shirodhara along with disease specific internal medicines. The ISI score before treatment of 26 came down to 1 after treatment and was maintained during 3 months follow up. This displays the complete remission of the disease without the use of habit-forming internal medication.
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    Varieties of Classical Drug Kadamba
    (Mahadev Publications, 2024-03) Singh, Sanjeev Kumar; Mishra, Hari Shanker; Agarwal, Ajay; Shukla, Anil Kumar
    Kadamb an indigenous plant described in classical texts of Ayurved has a wide range of therapeutic potential. In Charak Samhita, it has been classified in the group of drugs indicated in the management of pain (Vednasthapan Mahakashya). Among various indications, it has been reported to be used in the treatment of vitiated semen, as an astringent in healing of fractured wounds, hemorrhagic conditions, dyslipidaemia, diseases of female genital tract, as complexion promoting and alexipharmic. In classical texts, at least four varieties of Kadamb have been described. There has always been some controversy regarding botanical identity of different varieties of Kadamb described in classical texts. Present paper is a serious attempt towards establishment of botanical identities of different types of Kadamb described in classical text of Ayurved on the basis of exploration of literature substantiated by observations of field survey.
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    An Ayurvedic Perspective About Duchenne Muscular Dystrophy
    (Mahadev Publications, 2024-03) Patil, Ashwini A.; Kate, Rutuja Rahul
    Duchenne muscular dystrophy is a neuromuscular disease. This is an X-linked recessive disease caused by mutations in the dystrophin protein gene located on the short arm of the X chromosome, in the Xp21 region. It causes progressive muscle weakness due to wasting of muscle fibers. It causes loss of ability to stand, walk, and move before age 10; most patients die in their 20s. Since there is no specific treatment in any medical system and the prognosis of the disease is uncertain, if we start treatment at an early stage, children with DMD can walk, it can slow or stop progressive muscle degeneration. DMD cannot be directly related to a single disease in Ayurveda. Most major neuromuscular disorders are determined by Vata dosha. In Ayurveda, this pathogenesis can be clearly understood by the concept of Adibala Pravrutta Vyadhi (genetic disease). Here the pathogenesis is due to Beeja Bhagavayava Dusti (partial chromosomal defect) leading to Mamsa Vata Dushti.
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    Effect of Guggulu Tiktakam Kashayam in Uterine Fibroid
    (Mahadev Publications, 2024-03) Sunil, Swathy; Thomas, Giby; Balakrishnan, Maya
    The most common benign uterine tumours affecting women in reproductive and perimenopausal stages are fibroids or leiomyomas. There is strong evidence that estrogen and progesterone promote the growth of fibroids, despite the fact that their exact aetiology is still unclear. This is because fibroids seldom arise before menarche and retreat after menopause. The most prevalent reason for hysterectomy is fibroids. Menorrhagia, polymenorrhoea, metrorrhagia, intermenstrual bleeding, infertility, repeated abortions, pain and pressure feelings, abdominal lumps, and vaginal discharge are a few of the symptoms they exhibit clinically. In Ayurveda there is no exact correlation for uterine fibroid. Fibroids can be considered as Mamsa Grandhis, one among the Grandhis described by Charaka and Vagbhata. They increase the surface area of the endometrial tissue in the uterus when present, causing excessive bleeding, pressure feelings, dysmenorrhea, and even infertility. Vata-Kapha predominant Tridoshas have a role in the aetiology of the Granthi Roga, necessitating the use of Vata-kaphahara medicines. As Granthi can also be caused by Mandagni, in Granthi chikitsa we can make use of Dravyas that are Deepana pachana. According to Acharya Susrutha, Sopha Chikitsa is included in the Apakwa Granthi chikitsa. In Mamsa granthi chikitsa, Shothagna, Lekhana, Chedhana, and Vatanulomana dravyas may be utilised. Asrigdara chikitsa and Raktapitta chiktsa can be used to treat fibroids when heavy, prolonged menstrual cycles are present. A 38 year old lady was presented with complaints of heavy, prolonged bleeding during menstruation along with lower abdomen pain. On USG she was diagnosed with uterine fibroids. Guggulu tikitakam kashayam was given for 3 months and after follow up symptoms were evaluated. She was relieved from prolonged heavy bleeding during menstruation and lower abdomen pain. From this case report, it is evident that Guggulu tiktakam kashayam is effective in uterine fibroids