International Journal of Ayurveda and Pharma Research

Permanent URI for this collection

https://imsear.searo.who.int/handle/123456789/149872

Editor in Chief: Dr. B. Srinivasulu

ISSN: ISSN : 2322-0910 (Online) 2322-0902 (Print)

Frequency: 6 issues a year

Language: English

Online peer reviewed journal

Web site: https://ijapr.in/

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Now showing 1 - 20 of 1025

Asphaltum Punjabianum (Shilajit): Unraveling Myths with Scientific Evidence
(Mahadev Publications, 2025-06) Iqubal, Ashif; Rehman, Sayed Abdur; Khan, Nausheen; Qadir, Abdul
Shilajit is a mineral-rich resin that has a long history of use as a rejuvenator (Rasayana) in Ayurvedic medicine to treat various ailments such as arthritis, infertility, and cognitive decline. Although it is becoming increasingly popular, with more scientific validations, many myths still surround its actual clinical potential. This review directly debunks several persistent myths about Shilajit based on a critical evidence-based analysis. Among the key myths addressed is the notion that only men should take Shilajit, that it is solely a sexual health enhancer, that it works acutely, and that its supplements can be contaminated, rendering them inherently unsafe or unnatural. According to scientific sources, Shilajit is beneficial for both men and women, and it has been proven to contribute to bone health, metabolic processes, antioxidation, and cognitive enhancement. Rather than acting as an acute stimulant, Shilajit functions more as a slow-acting adaptogen that must be taken continuously over several weeks to produce observable physiological adaptations. It is also well-tolerated even in very high doses, as indicated by its toxicological and clinical safety data, provided it is purified. The concerns regarding contamination are addressed through purification, with the majority of certified products meeting global safety standards. Secondary myths, including the belief that Shilajit causes constipation, is inadvisable to use in summer, or leads to kidney stones, are also disproven by clinical and preclinical evidence. Ultimately, one can conclude that Shilajit is an effective and safe multilateral nutraceutical with diverse therapeutic potential. This review advocates for its incorporation into modern healthcare through science-based, myth-busting integration and challenges clinicians to base their recommendations on usage grounded in empirical evidence and quality assurance.
Managing Anovulatory Infertility Through Ayurveda: A Journey to the Birth of a Healthy Baby
(Mahadev Publications, 2025-04) Arora, Jyoti; N.V, Gayathri Bhat
Anovulation as understood in Ayurveda, can be correlated with terms such as Alpapushpa/Nashtartava arising primarily due to vitiation in majorly Vata dosha, Rasavaha srotodushti and Agnimandya. This case report highlights the successful Ayurvedic management of a 26-year-old woman with anovulatory infertility who had been unable to conceive for three years. After undergoing extensive allopathic treatments without success, she opted for Ayurvedic management, which included Virechana and Uttara basti. The combination of these treatment helped restore Shuddha Kshetra (uterus), balances the Agni, and proper formation and improvement in quality of Artava. Result: After three months of Ayurvedic management, the patient successfully conceived and delivered a healthy baby. This case underscores the potential of Ayurvedic approach in managing anovulatory infertility and improving reproductive outcomes.
Pharmaceutical Standardization of Amapachaka Vati: A Herbo-Mineral Formulation
(Mahadev Publications, 2025-04) Rathod, Deepika; Vyas, Kruti
Introduction: Standardization of formulation is essential to certify their quality, purity and reproducibility. The standard of an Ayurvedic product can be assessed by analysing the analytical parameters of raw drugs, in-process materials, and the finished products. Amapachaka Vati is a well-known Ayurvedic herbo-mineral formulation which is mentioned by Chikitsapradip in Agnimandhya and Ajirna. Till date, no work has been done on pharmaceutical standardization of Amapachaka Vati. The present study was aimed to develop Standard Manufacturing Procedure (S.M.P.) of Amapachaka Vati. Materials and methods: In pharmaceutical process, 3 batches of Amapachaka Vati were carried out with the Shodhana procedure of required ingredients. Organoleptic and physicochemical analysis of raw, in-process and finished product were done. HPTLC and heavy metal analysis of finished product were also carried out. Results: In all three batches of Amapachaka Vati average 97.11% yield was found. Prepared Vati was greenish brown in color with characteristic odor. Physical parameters of Vati were in compliance with the general consideration of IP standards. HPTLC profile shows 6,5,8 peaks in 254, 366, and 540 nm. Conclusion: The preparation method of Amapachaka Vati carried out here can be considered as Standard Manufacturing Procedure (S.M.P.) as no previous standards are available for this preparation. Evaluated parameters for Amapachaka Vati can be used in future reference as a standard.
Ayurvedic Management of Asrgdhara
(Mahadev Publications, 2025-04) S.N., Namitha
Asrgdhara is a condition of ‘Raja pradeerana’, that is excessive flow of Raja or Arthava. One who follows the Nidana sevana like Lavana, Amla, Guru aharas, Snigdha aharas, Adhyashana, h/o Garbha pata etc. can result in Asrgdhara. This can be corelated to abnormal uterine bleeding. Present case study is about a patient with heavy menstrual bleeding with dysmenorrhea and passage of clots after attaining menstruation following her delivery and irregular cycles since menarche. In modern she was suggested for hysterectomy since her family is completed but patient denied. Here, after taking a detailed menstrual and personal history, the Doshas involved were analysed as Vata and Kapha. Since Asrgdhara is a Basti Sadhya vyadhi and following the Samanya chikitsa, the treatment plan was done. Treatment plan included Picha basti and required internal medications. Patient had significant symptomatic relief with gradual reduction in clots to no clots, reduced dysmenorrhea and also the cycles became regular within 3 months of intervention. This case is a perfect example for conditions where even after suggesting surgical management, how Ayurveda helps in leading a healthy life by bringing the condition under complete control.
A Review Article on Hinguvadiagada in Vrichika Visha
(Mahadev Publications, 2025-04) M, Monika; SR, Prasanth
Agadatantra, a specialized branch of Ayurveda, focuses on the symptoms and management of poisons. Poisons are mainly classified into Sthavara and Jangama. Vrichika visha, a type of Keetavisha under Jangama visha, is known for its neurotoxic effects. The Ashtanga Hridaya Uttarasthana describes Hinguvadi Agada in the Keedaloothadi Visha Pratishedha Adhyaya as an effective formulation for managing Vrichika Visha. This simple herbomineral preparation includes Hingu, Haratala, and Matulunga and is administered in the form of Lepa and Anjana. Classical Ayurveda texts classify scorpions into three types based on the potency of their venom: Manda, Madya, and Mahavisha. While Lepa is effective for the local management of all three types of Vrichikadamsa, the Gutika-anjana form addresses systemic toxicity associated with Madya and Mahavisha types. The selection of ingredients in Hinguvadi Agada, especially Hingu and Matulunga, focuses on managing pain - a predominant symptom in scorpion stings. Acharya identified it as the best remedy for scorpion envenomation among the various available treatments due to its multidimensional pharmacological action. This article aims to explore the ingredients, preparation method, and probable pharmacological mechanisms of Hinguvadi Agada in neutralizing scorpion venom. Additionally, its possible applicability in managing other neurotoxic envenomations, such as cobra and krait bites, is discussed, highlighting its potential as a versatile antidotal yoga in Ayurvedic toxicology.
Sigrusireeshadi Yoga in Mandalivisha Chikitsa
(Mahadev Publications, 2025-04) P, Praseela; S R, Prasanth
Agadatantra is one of the eight branches of Ayurveda that deals with toxicology. It primarily focuses on the study, prevention, diagnosis, and treatment of various toxic conditions affecting humans. Kerala has a rich and distinct tradition of Visha chikitsa renowned for its specialized therapies and effective management of venomous bites, food poisoning and environmental toxins. Many Malayalam texts that offer practical insights into toxicology, antidote formulations and indigenous treatment methods. Prayogasamuchaya is one among them which contain numerous formulations that are highly effective in managing various types of poisoning, venomous bites, and toxic conditions. Sigrusireeshadi yoga is explained in Triteeya paricheda ‘Mandali visha chikitsa’ of Prayogasamuchaya. It is indicated for external application in Mandali vishaja sopha. Swelling is the predominant symptom of viper bite, that requires emergency management. This Yoga contains 5 ingredients, including Sigru, Sireesha, Punarnava, Aswagandha and Sundi. This article aims to discuss the possible mechanism of action of Sigrusireeshadi yoga by analyzing its pharmacological properties. And the probable mode of use of this yoga in other Vishaja sopha.
Significance and Utility of Raktashali (Red Rice) in Ayurveda - A Narrative Review
(Mahadev Publications, 2025-06) Kotur, Pragati V; Gadad, Geeta G
Raktashali, or red rice, recognized for its distinctive red bran and unrefined nature, holds a place of prominence in Ayurveda for its nutritional richness and therapeutic potential. Ancient Ayurvedic scriptures- including the Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, and Bhavaprakasha Nighantu repeatedly affirm Raktashali’s ability to harmonize the Tridoshas Vata, Pitta, and Kapha. It is described as having a sweet taste (Madhura rasa), cooling energy (Shita virya), light digestive quality (Laghu), and nourishing effect (Pushtiprada), making it especially beneficial in conditions such as fever, inflammation, ulcers, and overall physical debility. Ayurveda regards food as fundamental to health, and Raktashali is classified as Nitya Sevaniya Ahara, a food suitable for daily consumption owing to its role in tissue nourishment, digestive support, and immune modulation. Its applications are extensive: it plays a vital role in Samsarjana Krama, the graduated dietary regimen following Panchakarma therapies; it is recommended during monsoon (Varsha Ritu) to rekindle digestive strength (Agni); and it serves as a traditional staple in regions like Coastal Karnataka and Kerala. Modern nutritional science corroborates these benefits, identifying high levels of antioxidants, flavonoids, iron, and zinc, along with a low glycemic index that supports heart health, reduces inflammation, and aids in glycemic control. Additionally, its bran is rich in bioactive compounds, such as tocopherols, tocotrienols, and catechins- known for liver-protective and anticancer properties. By synthesizing ancient Ayurvedic wisdom with current scientific evidence, this review underscores Raktashali’s role as a versatile functional grain suitable for both therapeutic use and everyday nutrition in preventive and integrative healthcare models.
A Comprehensive Analysis of Anger from the Perspective of Ancient Indian Literatures, Ayurveda and Western Psychology
(Mahadev Publications, 2025-06) Saha, Soumyadip; Ray, Sukalyan
Different Indian literatures have discussed the genesis of anger along with its different negative impact with approaches to overcome it, among which Ramayana, Mahabharata and Bhagavad Gita are principal ones. Apart from them various other texts like Patanjali’s Yoga Sutras, Manusmriti, Chanakya Niti Darpana etc. also have discussed the various aspect of anger. Likewise principal Ayurvedic texts like Charaka Samhita and Sushruta Samhita also addressed this topic and discussed thoroughly about its genesis, character, assessment and its role in causation of diseases. Likewise, in recent times many modern psychologists also have investigated anger as a global social problem and threw light on its physiological and cognitive aspects. Discussions: Patanjali’s Yoga Sutra viewed anger as one of the Chitta Vrittis as well as among Pancha Klesha. Patanjali advised to overcome anger by habituating the mind into contrary ideas. Manusmriti viewed anger as a negative emotion which has lots of repulsion in human’s social and personal life. Likewise, other texts on morality and ethics like Chanakya Niti Darpana, Panchatantram, Hitopadesha etc. have similarly analysed anger and its negative impact. Primarily Charaka Samhita and Sushruta Samhita also described anger as product of vitiation of Pitta Dosha as well as Raja - Tama Dosha. In addition, Charaka Samhita also discussed the method of assessment of anger, its anthropological genesis in Kali Yuga, its importance as forbidden object in various compromised conditions. They have discovered new facts like role of amygdala in provocation of anger. Based on all these findings, the present authors have chalked out some fundamental approaches of anger management from the perspective of ancient Vedic tradition, Ayurveda as well as modern psychology. Conclusions: The present study is a novel approach in discussing anger with all its psychopathology, impact on personal and social life as well as its management in a comprehensive manner showing the perspectives of age-old Indian literatures, various texts of Ayurveda as well as modern psychology.
Standardization and Analytical Profiling of Shirashooladi Vajra Rasa: A Comparative Study with Marketed Samples
(Mahadev Publications, 2025-06) Tambe, Ganesh Ananda; Badyal, Sakshi; Yadav, Pramod; Prajapati, Pradeep Kumar
Shirahshooladi vajra rasa is a potent mercurial preparation widely used in the treatment of Shirahshoola (headache). It consists of processed mercury and sulphur, incinerated copper and iron along with other herbal ingredients like Triphala, Yastimadhu, Pippali, Shunthi, Vidanga, Dashamula and Guggulu. This formulation is enriched with Vatashamaka (mitigates Vata dosha) herbs like Dashamula, Guggulu etc. Aim and objective: This study aims at developing standard manufacturing procedure (SMP) and analytical parameters of Shirahshooladi vajra rasa along with analysis of its available marketed samples. Methodology: The formulation was prepared in three batches to standardize its pharmaceutical processing. Also, six other available different samples of the Shirashooladi vajra rasa were collected from market and all the seven samples were assessed for quality control parameters to compare their quality. Observations & Result: All the quality control parameters conducted for inhouse and marketed samples were not similar, some variations were found. Conclusion: The average yield obtained from three batches is 99.1%. Analytically, slight variation was observed among all the samples.
Human Gut Microbiome in Health and Disease-An Ayurvedic Perspective
(Mahadev Publications, 2025-06) T, Ranjana Janardhanan; Madhu, P M
The human gut microbiome refers to the complex collection of trillions of microorganisms residing in the gastrointestinal tract, which play a crucial role in homeostasis and disease. Over the past few years, our understanding of the microbiome has evolved significantly, highlighting its impact on a wide range of physiological and pathological processes. This emerging knowledge has transformed health sciences, revealing the gut microbiome’s essential role in maintaining metabolic, immune and neurological health. In this context, Ayurveda, a traditional system of medicine originating in India, has long emphasized the importance of gut health. Ayurveda’s integrative approach of dietary guidelines, lifestyle modifications, treatments, and practices aimed at restoring balance within the body. The "Agni" (digestive fire) in Ayurvedic terms, is considered a central element of health. Ayurveda teaches that proper digestion is essential not only for physical well-being but also for mental clarity and emotional stability. Ayurveda offers supportive view into modern microbiome science by focusing on the balance of bodily humours (Doshas) and recommending specific herbs, probiotics, and prebiotics that can support gut health. In-depth analysis of Ayurvedic concepts and practices in line with the theory of microbiome proves that they are aimed at maintaining a balanced gut flora. As microbiome research continues to evolve, Ayurveda's emphasis on individualized care, nurturing the gut microbiome and enhancing overall health.
Critical Appraisal of Lakshanaskandha of Bruhat-Tryaee with special reference to Pandu
(Mahadev Publications, 2025-06) Rajendrasinh, Rajput; Pandya, Darshna; Surati, Karan
Lakshanas (symptoms and signs) are the backbone of clinical practice, whether in the form of physiological or pathological condition, in context of diagnosis or treatment one need to rely on the manifested symptoms only. Here it is very much important to understand pathophysiology of Pandu in different given context to understand seriousness of the condition and to plan the treatment accordingly. Materials and Methods: Mainly Bruhattrayee i.e., Charaka Sahmita, Sushruta Sahmita and Ashtanga Hridaya with its well-known commentary was selected as main text and Pandu has been searched. Results: It appears 23 times in Charaka Samhita, 21 times in Sushruta Samhita, and 8 times in Ashtanga Hrudaya. In the context of clinical signs and symptoms, references to Pandu were identified as follows: 2 instances as Purvarupa, 12 as Rupa, 7 as Upadrava, 2 as Ari?h?a, and 29 instances categorized under miscellaneous references. Discussion: The therapeutic approach to Pandu Roga must be individualized and rooted in a comprehensive understanding of its Samprapti. The selection of treatment modalities should be based on the underlying aetiology. Conclusion: Each symptom has its own specific Samprapti. Different symptoms can arise from various mechanisms. To effectively address Pandu, it is crucial to evaluate the causative factors and pathogenesis and plan the treatment accordingly.
Ayurvedic Management of Female Androgenetic Alopecia (Khalitya)
(Mahadev Publications, 2025-06) V, Varsha; Palak; Mandal, Sisir Kumar
Androgenetic Alopecia (AGA), or pattern baldness, is a common form of non-scarring hair loss primarily affecting the scalp, with a higher incidence in males. Genetic, hormonal, and environmental factors contribute to its pathogenesis. AGA significantly impacts psychological well-being. Conventional treatments like minoxidil, finasteride, and corticosteroids offer temporary benefits but are associated with adverse effects and recurrence of symptoms, prompting the need for safer alternatives. Methods: A 32-year-old female presented in November 2024 with gradual vertex hair loss and a SALT score of 28%. She was treated for one month with Jalaukavacharana (leech therapy), external application of Shirolepa (herbal paste), and internal Rasayana (rejuvenative) medications. Result: By the end of treatment, the patient showed visible improvement in scalp condition and hair density, with the SALT score reducing to 12%. Discussion: The classical Ayurvedic approach effectively managed AGA by enhancing blood circulation and follicular nourishment, offering a safe and holistic alternative to modern therapies.
Krishna’s® She Care Ayurvedic Juice: A Literature-Based Review of its Polyherbal Approach to Women’s Hormonal Balance
(Mahadev Publications, 2025-06) Daga, Shrawan; Shrivastava, Pradeep; Sharma, Divya
Krishna’s® She Care Juice is a polyherbal preparation that is intended to promote women's reproductive health, especially in the management of conditions such as Polycystic Ovary Syndrome (PCOS), irregular menstrual cycles, dysmenorrhea, and other gynecological disorders. This review summarizes the existing scientific and clinical literature regarding the major herbal constituents of the product i.e., Saraca asoca, Berberis aristata, Zingiber officinale, and Triphala emphasizing their unique roles in modifying hormonal equilibrium, anti-inflammatory actions, uterine health promotion, and enhancing metabolic indices. Clinical trials of S. asoca establish its effectiveness in curtailing menstrual bleeding and dysmenorrhea. B. aristata demonstrated insulin-sensitizing activity, useful in the management of PCOS, while Z. officinale has evidence based on randomized controlled trials for its analgesic and hormone-modulating action. Triphala, exhibiting antioxidant and adaptogenic activities, proved useful in the control of menstrual disorders, Premenstrual syndrome (PMS), and endometriosis. While encouraging evidence exists for each of these individual herbs, a major gap still exists in direct clinical evidence comparing the safety, tolerability, and efficacy of the combination formulation as it occurs in Krishna’s® She Care Juice. This serves to underscore the imperative need for pre-clinical mechanistic studies and rigorously designed clinical trials to establish its therapeutic merits, refine dosing regimens, and define safety profiles. The novel traditional application and corroborative findings on its components render Krishna’s® She Care Juice an interesting subject for future investigation, with the potential to become a standardized, evidence-based Ayurvedic treatment for women's health.
Incompatible Foods and Neurodevelopmental Disorders in Children: A Review of the Evidence
(Mahadev Publications, 2025-06) Jaisawal, Vaibhav; L, Anju K.; Jaiswal, Aakanksha; Yadav, Suraj Ramchandra; Rajput, Narendra Kumar Singh
Neurodevelopmental disorders such as Attention Deficit Hyperactive Disorder (ADHD), autism and anxiety are becoming more common in India, posing a significant economic and social burden on the country. Despite extensive research the exact causes of ADHD and autism remain unclear. Both conditions are multifactorial involving genetic, environmental and biological factors. Poor diet being a significant contributing factor for the increasing prevalence of neurodevelopmental disorders. Objective: Investigate the relationship between diet and neurodevelopmental disorders like ADHD and autism, and explore Ayurvedic principles in understanding this relationship. Data source extensive research on neurodevelopmental disorders, Ayurvedic texts, and modern scientific studies on diet's impact on brain development and function. Review methods comprehensive review of existing research on neurodevelopmental disorders, Ayurvedic principles, and diet's impact on brain health, considering modern food consumption patterns. Result: Poor diet is a significant contributing factor to neurodevelopmental disorders. Consuming preserved foods, high sugar, and unhealthy fats leads to inflammation, oxidative stress, and disruption of the gut-brain axis. Conclusion: Ayurvedic principles provide valuable insights into the relationship between diet and neurodevelopmental disorders. Identifying new food incompatibilities relevant to modern food consumption patterns may help develop dietary interventions to prevent or manage these disorders.
Integrating Ayurveda into Addiction Medicine: A Pilot Trial of Ksheerbala Taila Nasya for Nicotine De-Addiction
(Mahadev Publications, 2025-06) Amrita, Nayek; Shawan, Barik; Pallabi, Mukherjee
Commonly found in tobacco derivatives, nicotine is one of the most common forms of addiction in today’s world. With growing dependency on nicotine irrespective of gender or standard of living humans are exposed towards basic to most fatal diseases. According to WHO- global health report, one-fourth (24.9%) of the population including both sexes are nicotine dependent, 40.3% men and 9.5% women. Although there have been many attempts on nicotine de-addiction trials most have failed or relapsed. In this study 10 nicotine dependent individuals were randomly selected from OPD. They were given Nasya therapy with Ksheerbala oil (10 drops each nostril) followed by Tikshna Snaihika Dhumapana after Mukha Abhyanga with Tila taila and Vastra Swedana for a period of 7 days in indoor department with Pratimarsha Nasya (2 drops each nostril) of same oil in the next 7 days. All the 10 cases showed marked decrease in nicotine dependence with highly significant p-value of 0.0019. Nicotine being highly addictive is an anxiolytic drug affecting synaptic junctions of central nervous system. Nasya one of the five Karmas of Panchakarma, is a simple procedure that can be done on OPD basis giving admirable results in de-addiction.
Formulation and In Vitro Evaluation of Gabapentin Controlled Release Tablets Using Natural Polymers
(Mahadev Publications, 2025-06) Sruthi, V; Alagarsamy, V; Bose, P. Subhash Chandra; Saritha, D; Reddy, P. Srikanth
This research set out to find the best way to use various grades of controlled-release polymer. To create a new one that would be just as effective as the original, but cheaper, and of better quality. The dosage form was designed using Hydroxypropyl Methyl Cellulose (HPMC K15MCR) as matrix builders. Research on the compatibility of medication and polymer was carried out. The flowability of the powder blend was optimized after studying the blend. Uniformity Compressing free-flowing powder directly into tablet form was the method of choice. They were successfully combined with the HPMC, MCC, and DCP networks. In order to compare different dissolution characteristics, we also presented the mean dissolving time. Clinical trials have shown that controlled-release gabapentin tablets are formulated by direct compression outperforms its immediate-release counterparts in terms of therapeutic efficacy.
A Conceptual Study of Agya Chakra and its Neuro-Anatomical Correlation in Modern Science
(Mahadev Publications, 2025-06) Joshi, Karishma; Goswami, Madhavi
This paper aims to illuminate the parallels between the Agya Chakra, the sixth energy center among the Shad chakras (six main Chakras) described in Yogic traditions- particularly its structures with modern neuro-anatomy. In Yogic philosophy, Chakras are the dynamic centers or vortices of Pranic energy, each located at specific points within the body. They regulate the flow of Prana (life force energy), thereby influencing both structural integrity and physiological processes. When activated through various Yogic practices, these Chakras help modulate psychophysiological functions. Each Chakra is traditionally associated with distinct neuronal plexuses and sub-plexuses, which correspond to specific internal organs and their physiological roles. Focusing on the Agya Chakra, located between the eyebrows, the study integrates classical yogic descriptions with contemporary anatomical knowledge. Based on the position, structure, and functional attributes described in Yogic literature, a strong correlation is observed between the Agya Chakra and the hypothalamic nuclei along with associated neural plexuses. To validate this correlation, a cadaveric study was conducted, which further supported the anatomical resemblance between the Agya Chakra and the hypothalamus and its neural networks. The findings suggest that the Agya Chakra can be interpreted as a symbolic representation of the hypothalamic region within the framework of integrative anatomy.
Ayurvedic Management of a Large Cystic Thyroid Nodule
(Mahadev Publications, 2025-06) Aravind, Vrinda; Balakrishnan, V K V
A thyroid nodule is a very common palpable swelling in the thyroid gland. About 95% of thyroid nodules are benign in nature. Thyroid nodules require assessment using suitable diagnostic tests and imaging techniques. Any nodule greater than 1cm should be biopsied to check for malignancy. Thyroid nodules occur more frequently in women than men. Here, presenting a case of a lady with a large cystic thyroid nodule in the left lobe, managed under the outpatient department. She presented with rapidly increasing swelling in her neck associated with pressure symptoms and spasming of hands and legs for 4 days. She was prescribed a combination of Varanadi Kashaya, Punnarnavadi Kashaya, Kanchanara Guggulu, Chandraprabha Vati and Gokshura Choorna internally and Karutta Vattu for external application. By the first follow-up itself (after 10 days), the patient felt symptomatic relief. Investigations repeated after 50 days showed considerable change in the size of the cystic nodule. Similarly, there is cosmetic resolution of the swelling at the 50th day follow up which is evident from the photographs provided.
A Pharmacological and Therapeutic Plant Review of Bhallataka (Semecarpus Anacardium) in Classical and Modern Medicine
(Mahadev Publications, 2025-05) Kumar, D. Mohan; Durga, Ch. Sri
Bhallataka (Semecarpus anacardium Linn.), commonly known as the marking nut tree, is a widely utilized medicinal plant in Ayurveda, recognized for its diverse pharmacological activities. Classical Ayurvedic texts such as Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, and various Nighantus extensively document its properties, formulations, and therapeutic indications. It is classified under Upavisha (semi-poisonous drugs), requiring meticulous purification (Shodhana) before internal use. Various parts of the plant-particularly the seed, kernel (Majja), fruit, and oil-exhibit actions such as Deepana, Pachana, Krimighna, Shukrala, Rasayana, and Kaphavatahara. These properties make Bhallataka valuable in treating conditions like Kushtha (skin disorders), Arsha (piles), Grahani (IBS), Gulma (abdominal masses), Pandu (anaemia), and Vatarakta (gout). Modern pharmacological research has corroborated many classical claims, demonstrating its anti-inflammatory, immunomodulatory, antimicrobial, antioxidant, and anticancer effects. Phytochemical investigations reveal bioactive constituents like bhilawanol, semecarpol, anacardol, and biflavonoids responsible for its therapeutic efficacy. Despite its efficacy, improper handling may cause severe toxic reactions; hence, traditional antidotes and dietary guidelines (Pathya-Apathya) are crucial during administration. This review compiles comprehensive information from classical and contemporary sources to present a holistic understanding of Bhallataka-from its botanical description, purification techniques, therapeutic actions, and formulations to modern evidence-based validations highlighting its integrative significance in traditional and modern medicine.
Efficacy of Selected Ayurvedic Treatment Protocol Against Standard Ayurvedic Protocol in the Management of Meniscal Injuries- A Randomised Controlled Non-Inferiority Trial
(Mahadev Publications, 2025-06) P.N, Mrudula; H, Rejani
Meniscal tears are the second most common knee injuries which may lead to chronic pain, reduced mobility, and a higher risk of osteoarthritis if untreated. It may be correlated with Bhagna in ayurveda. Sushrutacharya, in Bhagna chikitsa, recommends Bandhana and Snehaseka for Janu Bhagna, followed by rehabilitative exercises. Methodology: This study aimed to compare the efficacy of a selected Ayurvedic protocol with a standard treatment protocol in MRI-confirmed meniscal injuries. 24 participants were randomly divided into two groups of 12 in each group and treated for 35 days at VPSV Ayurveda College, Kottakkal. Assessments were done on Day 0 and Day 35, with a follow-up after one month. Both groups received Bandhana for 3 weeks. The study group underwent Shashtika Taila Seka and exercises, while the control group received Dhanwantara Taila seka, Shashtika Pinda Sveda, and Matravasti for 2 weeks. Internal medications such as Dhanwantara Kashaya, Lakshaguggulu Vati, and Gandha Taila were given to both groups. Results: Statistical analysis showed improvement in both groups, with the study group showing slightly better symptom relief. The mean difference between the study and control groups was tested for non-inferiority using one-sided t-test and study group was found to be non-inferior. Conclusion: The selected Ayurvedic protocol was found non-inferior to the standard Ayurvedic protocol in managing meniscal tears and improving quality of life.

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