International Journal of Ayurveda and Pharma Research

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https://imsear.searo.who.int/handle/123456789/149872

Editor in Chief: Dr. B. Srinivasulu

ISSN: ISSN : 2322-0910 (Online) 2322-0902 (Print)

Frequency: 6 issues a year

Language: English

Online peer reviewed journal

Web site: https://ijapr.in/

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Now showing 1 - 20 of 891

A A Clinical Study To Evaluate The Combined Effect Of Kesharsiddha Ghrit Nasya And Yog Basti Along With Tab. Pathyadi Ghanvati In Ardhavbhedaka W.s.r. To Migraine
(Mahadev Publications, 2019-11) Kendre, Kranti; Salunke, Amrut
Migraine is the disease of recurrent attack of headache which usually involves half of head. It is felt as throbbing type of pain and associated with various symptoms like, Nausea, vomiting, Photophobia etc. Its acute attacks are treated with different analgesics or ergotamine preparations. A modern medicine gives instant relief from symptoms but may cause drowsiness, insomnia, depression etc. As compare to that, Ayurveda has variety of natural plant medication and Panchakarma therapeutic procedures in management of Ardhavabhedaka. Thus, the study was selected to evaluate the efficacy of Ayurvedic Panchakarma therapy in migraine. The duration of the treatment was 30 days. Out of 17 migraine patients who were offered this Ayurvedic treatment, 12 patients completed total 30 days treatment protocol. Detail history and examination of each patient were done. Kesharsiddhaghrit Nasya and Dashmul kwath yog basti given along with Tab. Pathathyadi Ghanvati. Evaluation was done. Total disappearance of headache and associated symptoms at completion of treatment was observed in 66.66% patients. Mild episode of headache without need of any regular treatment was observed in 8.33% of patients. Low intensity of pain along with their regular treatment was observed in 16.66% of patients. Very mild improvement in 8.33% patients and no worst pain was noted in a single patient during treatment (0.0%); respectively. From the results and observation obtained from this study it can be concluded that Ayurvedic Panchakarma therapy showing better results in Ardhavabhedaka. No any harmful side effects were found during this entire study.
Abhraka Bhasma A Boon Of Ayurveda To Mankind: A Review
(Mahadev Publications, 2019-06) Bhokardankar, Prashant Sakharam; Mane, Sandeep Gorakh; Khairanar, Bhupendra Prakash
Abhraka bhasma is a popular Rasashastra medicine in Ayurveda stream. It is basically herbomineral preparation used by all Ayurvedic Vaidyas since long time. Abhraka is basically Mica (Biotite). Bhasma is nothing but incinerated ash. Rasashastra is an Indian metallurgy which deals with several minerals and herbomineral preparations specially Bhasmas. There are several popular bhasmas in Ayurveda but there is great demand of this Bhasma in Ayurvedic vaidyas. Use of this bhasma is in multiple disorders, so could be consider as a major Ayurvedic drug. Published details scientific literature on Abhraka bhasma by various research scholars, internet & pharmacopeias were reviewed. The review was done to find physicochemical characteristics as well as standardization studies done on Abhraka bhasma. Also attempt is to made to find scientific studies done on Abhraka bhasma. Need of hour to evaluate its efficacy value as potential Ayurvedic drug in various disorders. As well as importance of Abhraka bhasma as an evidence-based drug. Review of literatures and scientific studies of Abhraka bhasma clearly indicate that there are lot of studies is done on Abhraka bhasma’s specially it’s physicochemical characteristics, standardization as well as it’s therapeutic uses. Abhraka bhasma is indicated in several ailments like Diabetes, Asthma, Paralysis, Neurological condition, Tuberculosis and Acid peptic diseases.
Absence of Musculocutaneous Nerve: A Rare Anatomical Variation
(Mahadev Publications, 2022-04) Kanthi, Giridhar M; Valsan, Sunitha
Neural variation of the brachium constitutes a significant anatomical and clinical entity. The absence of Musculocutaneous Nerve is occasional in humans and accordingly there may be unforeseen clinical implication regarding the atypical innervations of musculature otherwise supplied by the Musculocutaneous Nerve. The present study is an absence of Musculocutaneous nerve observed during our routine educational dissection, where the lateral cord of brachial plexus took over the area of supply of Musculocutaneous Nerve by giving both the muscular and sensory branches. Knowledge of these variations is important in surgeries and during the administration of regional anaesthesia near shoulder joint and upper arm.
Achara Rasayana-a Behavioral Therapy In Ayurveda To Promote Health And Happiness
(Mahadev Publications, 2018-01) Kumawat, Shreeram; Verma, Archana; Yadav, Sunil; Meena, K.L.
Rasayana Tantra is one of the eight major divisions of Astang Ayurveda. In Ayurveda, one of the major methods of presentation of positive health has been described i.e. Rasayana. There are many activities that promote health and happiness by engendering positive emotions and experiences, which in turn promote the production of Ojas. These activities are included in Achara Rasayana . Ayurveda strongly emphasizes prevention, promotion, cure and rehabilitation. For this, it advocates to follow the principles of health, observation of principles â€“ Dincharya (daily regimen), Ritucharya (Seasonal regimen), Ratricharya (Night routine), Sadvritta and Achar Rasayan (Ethical and Moral activities), Aahar (Food), Nidra (Sleep) and Brahmacharya (Regulated Action). Achara Rasayana is described in various texts. It means good conduct. It signifies the physical and mental conducts of a man and it has been designated as an Rasayana â€“ a vitalizer agent for entire span of life. This is a measure having no involvement of drugs and if it is sincerely taken into practice, it may replenish and maintain total life process free from ailments. A careful analysis of qualities of Achara Rasayana reveal that most of them are related with Mana, Dhi, Dhriti along with good conduct and these results in maximum benefit. The principles of Achar Rasayana are more relevant today than ever. It goes into the heart of the issue we are trying to overcome in order to be well and healthy. Environmental toxicity and the food chain we are accustomed to have threatened our lives. The integral connection between nature and man is an understatement.
Action Mechanisms Of Antibiotics Vs Natural Ingredients Against Microbes
(Mahadev Publications, 2020-02) Kamathewatta, Manika Dulanjali
Antimicrobial resistance is being identified as one of the major threats in the health sector and to humans. The main reason of development of the resistance is established as acceleration of the natural evolution of the bacteria due to unnecessary constraints provided by the antimicrobial agents. After exploiting and exhausting the available antibiotics, development of new antibiotics is proven to be an expensive and difficult task and therefore alternative solutions such as use of nanoparticles, bacteriophage, natural ingredients, and new mechanisms such as quorum sensing ability were staged. It is important to identify the mechanism by which each of these new ingredients act in bacteria and reaction in the host environment to avoid similar misuses and creation of resistance. This review focuses on summarizing action mechanisms of antibiotics and resistance mechanisms of microbes and gathering probable action and resistance mechanisms of herbal ingredients. Antibiotic action is mainly obtained by inhibiting a bacterial structure or specific metabolic activity that is necessary for survival of bacteria. Some plants in contrast do not focus on inhibiting bacteria but minimizing the effects on host by nullifying the toxins and improving the immunity. Some other plants can disrupt the communication between bacteria and biofilm formation. One of the most important ability of some herbal ingredients is to overpass the resistance and they are called inhibitors. With the inhibitors there are new possibilities of reintroducing antibiotics. Plants with bactericidal capacity must use carefully to avoid creating resistance and should conduct further research for calculating proper dosages.
Add on Effect of Sthanika Chikitsa in Second Degree Uterine Prolapse along with Standard Conservative Management, Pelvic Floor Exercise
(Mahadev Publications, 2024-12) Thomas, Giby; Nayanar, Thanooja
Uterine prolapse is a type of pelvic organ prolapse where the supporting pelvic structures of the uterus weakens and result in the descent of the uterus from its normal position. This condition may arise from the gradual failure of the supporting and suspensory structures of the uterus and vaginal wall over time. Most important conservative management involves pelvic floor exercises. When conservative management fails, surgery is the only treatment option. Yonirogas which show features of pelvic organ prolapse are Prasramsini, Andini, Phalini, Mahayoni and Vatiki. Among them, Prasramsini can be most suitably correlated with 1st and 2nd degree uterine prolapse[1]. The management principle of pelvic organ prolapse includes Vathika yoni roga chikitsa along with Sthanika chikitsa. Treatment mainly aims at Vathasamana, Brimhana, Sandhana, Balya and strengthening of pelvic floor musculature. This case report explores the add-on effect of Sthanika chikitsa particularly Yoni abhyanga, Yoni pichu dharana and Matra vasti with Dhanwantharam thailam and Avagaha with Dasamoola kwatha in second degree uterine prolapse with standard conservative management, pelvic floor exercise. Symptomatic relief and functional improvements were observed after 3 months of combined therapy, suggesting the additive benefits of integrating Sthanika chikitsa into standard conservative management.
Added Effect of Pratimarsha Nasya with Ksheerabala Taila (14 Aavartita) over Selected Yoga Techniques in Insomnia
(Mahadev Publications, 2023-01) V, Vrinda; Sunitha, V K; Bhadran, Sajitha
Insomnia is a prevalent psycho physiological sleeping disorder, included in the International Classification of Sleep Disorders-2 (ICSD-2). By definition insomnia is a difficulty in initiating or maintaining sleep, or both or the perception of a poor quality sleep. Insomnia leads to various social, interpersonal and occupational impairments. Clinical studies have proven that Yoga is effective in insomnia. Present study was to find out the added effect of Pratimarsha nasya with Ksheerabala taila (14 Aavartita) over selected Yoga techniques in relieving insomnia. As per Acharya Susrutha in Chikitsa Sthana, doing Pratimarsha nasya daily during evening hours (Sayamkala) renders Sukhanidraprabhodanam. A pre-post interventional study was performed in 40 participants both male and female, satisfying the inclusion and exclusion criteria. Out of 40 participants, 20 each were randomly allocated to Group I and Group II. In Group I, Pratimarsha nasya using Ksheerabala taila (14 Aavartita) was administered 1ml in each nostril at evening time along with the practice of selected yoga techniques during morning hours. In Group II, only selected Yoga techniques were advised. The study period was for 30 days. The pre & post changes in mean score value was assessed using Pittsburgh Sleep Quality Index (PSQI) score. The data was analyzed using unpaired t test, and was statistically significant with a p value ?0.01. Thus the added effect of Pratimarsha nasya with Ksheerabala taila (14 Aavrtita) over selected Yoga techniques in insomnia is more effective than selected Yoga techniques alone.
Addressing the Aging Process Through the Ayurveda Lifestyle Interventions and Adaptations
(Mahadev Publications, 2024-05) Patil, Vinita; Sharma, Vikram
The elderly population is growing worldwide, leading to an increased focus on geriatric care and promoting healthy aging. Ayurveda, an ancient Indian system of medicine, offers a holistic approach to healthcare that can be beneficial for addressing the unique needs of older adults. This research article explores the integration of geriatrics and Ayurveda, highlighting the potential benefits of Ayurvedic principles, lifestyle adaptations, and herbal remedies in geriatric care. By combining the wisdom of Ayurveda with modern geriatric practices, healthcare providers can offer comprehensive and personalized care to elderly individuals, enhancing their quality of life and promoting healthy aging. The field of geriatrics focuses on the healthcare needs of older adults, aiming to promote physical, mental, and emotional well-being in the elderly population. This study focus on enhancing the concept of geriatrics through the principle of Ayurveda related to lifestyle management. To minimize the functional decline and to enhance the quality of life in geriatric age group through the incorporation of Ayurveda lifestyle adaptation is the main goal of this paper. Lifestyle diseases are related with the people’s way of living. This is generally caused by lack of physical activity and unhealthy food habits. A healthy lifestyle must be adapted to fight the various age related disorders and diseases. Ayurvedic principles of health and disease focus on the concept of three Doshas: Vata, Pitta and Kapha. These are the three forces that determine the functioning of the body and mind. Although every person has all three Doshas, ??we will each inherit them differently. This is responsible for the differences in our characters, likes, dislikes, attitudes and behaviours.
Adulteration And Need Of Substitution Of Raw Materials – A Review
(Mahadev Publications, 2018-07) Shahane, Snehal; Tekade, Anand; Dive, Mukund; Daulatkar, Kavita
Experiencing challenges of modern medicine, globe is shifting towards the Ayurvedic theory of health management. In the treatment of disease use of medicine is practiced rampantly. This increased the demand of raw material exponentially. But, growth in production is still linear in nature. Fast depletion of resources is creating the major trouble. To meet the deficit, practices of adulteration and substitution are going on wildly. This adulteration and substitution became burning problem in industry threatening the integrity of Ayurveda. The deforestation, extinction or evolution of many species, insufficient knowledge, unauthenticated practices about identification, collection, storage and transport of raw material collectively resulted in adulteration. Strategic planning and integrated approach towards mass production, supply chain management, IEC, proper advocacy and knowledge sharing is needed to trim down the gravity of adulteration. “Prevention of Food Adulteration act 1954” describes technical definitions and guidelines for quality maintenance. Government is enforcing quality maintenance by implementation of “The Drug and Cosmetics Act 1940” For quality assurance, proper pharmacovigillance monitoring of raw materials and processes is very necessary. The concept of substitution is known in Ayurveda as it is enlightened prominently in Bhavprakash and Yogratnakar. However in scenario of crises, selection of substitute drugs may have upper edge over adulteration of the raw material. Scope of this article advocates that how adulteration and substitution are creating problems with respect to production of inferior quality medicines.
Age Related Neurodegenerative Disorders w.s.r to Dementia
(Mahadev Publications, 2022-07) Kantharia, Shivaranjani J; Gupta, SN; Patel, K. B.
Aging can be defined as the gradual anatomical and physiological decline which begins to after the achievement of sexual maturity. Vriddhavastha (senility) is Vata dosha prominent phase of life. Gunas (qualities) of Vata dosha are degenerative by the nature which is increased; they result in degenerative changes in the body in terms of Dhatukshaya, Ojakshaya and Balakshaya which result in Neuro degeneration. Dementia is the progressive deterioration of intellect, emotional control, behavior and motivation along with loss of memory. Vriddhavastha (aging) is Vata dosha prominent Avastha. Vata has some Guna (qualities) that get involved in the degenerative process in the body like Laghu guna and Khara guna which is act as Lekhaniya (scraping), Vishada guna has Kshalanashakti (elution power) and, Ruksha guna has Shoshanashakti (absorbability), etc. With increasing Vata dosha, these above Gunas are also be increased, might be together or separately and will initiate the process of degeneration in the body in the terms of Dhatukshaya, Ojakshaya and Balakshaya causing various degenerative diseases. Dementia is one among them. Symptomatology of dementia are similar to Vata vriddhi lakshana, Vata nanatmajavyadhi and Ojakshaya lakshana. Manifestation of the disease condition is purely due to degenerative changes in senile periods. The disease condition is not a reversible but with the healthy changes in dietary habits and lifestyle, the disease condition might be preventable and delayed.
Aggressive Behaviour Based on the Types of Agni Bala Among Young Adults
(Mahadev Publications, 2024-02) Gopeendran, Anupama; Manoj, R; M, Divya Devi
Agni is one of the main concepts that are dealt in Ayurveda. Agni is responsible for the digestion and metabolism of the ingested food. The types of Agni included are Visama agni, Tikshna agni, Manda agni and Sama agni. Aggression is often a harmful social interaction with the intention of inflicting damage or harm to others or on self. The independent variable and dependent variable is Agni bala and aggressive behaviour respectively. This study is attempted to study the difference on aggressive behaviour based on the Agni type among young adults. The hypothesis proposed was a null hypothesis which implied that there is no significance of Agni bala on aggressive behaviour among young adults. Data was collected using Agni bala assessment tool and Buss-Perry aggressive questionnaire. It is a quantitative study which has employed comparative research design. Comparative research design is used since there is a comparison among the Agni bala types (Visama agni, Tikshna agni, Manda agni and Sama agni). Random sampling was done and the total sample size is 180 young adults between the age group 18-30 years. ANOVA was the statistical test used for the study. The ANOVA test showed that there is no difference on the aggressive behaviour based on the Agni type since the significance level is 0.007. The results were calculated using Statistical Package for Social Sciences (SPSS). The hypothesis was accepted which indicate that the there is no significant difference on aggressive behaviour based on the type of Agni bala among young adults. The study concluded that there is no difference on aggressive behaviour based on the type of Agni bala among young adults.
Allergic Rhinitis: A Critical Modern Review
(Mahadev Publications, 2022-02) Chanchal, Narender; Kaul, Smriti; Agrawal, Riju; Singh, Daya Shankar
Allergic rhinitis addresses a hyperactivity of the resistant framework in any case harmless particles making a fiery reaction where none is required. Allergic Rhinitis is clinically represented by a mixture of two or additional nasal symptoms: running, blocking, itching and sneezing. Allergic rhinitis is regularly partitioned by age, seriousness, and duration of symptoms. Investigation represents how epidemiologic evaluations on the commonness of hypersensitive or allergic rhinitis shift considerably with whether both clinical appraisal and testing were utilized to make the determination. The treatment of allergic rhinitis should combine allergen avoidance, pharmacotherapy and allergen immunotherapy. Treatments of allergic rhinitis include intranasal corticosteroids, oral and topical antihistamines, decongestants, intranasal cromolyn, intranasal anticholinergics. First-generation and Second-generation oral antihistamines and intranasal corticosteroids are the most effective modality for treating allergic rhinitis. Immunotherapy is an efficient immune-modulating treatment that ought to be counseled if pharmacologic medical care for allergic rhinitis isn't effective or not tolerated. This article provides an overview of the prevalence, pathophysiology, diagnosis, and appropriate management of the allergic rhinitis.
An Alternative Approach to the Treatment of Arthritis
(Mahadev Publications, 2024-05) Upadhyay, Soumya
Arthritis, also known as joint inflammation, is the swelling and tenderness of one or more joints in the body. With the main symptoms being stiffness of joints and pain, arthritis can severely affect the quality of life. It worsens with age and typically shows itself in adult ages. This case study is of a very young, 19-year-old woman, who was diagnosed with rheumatoid arthritis at the age of 18. After Ayurvedic assessment, she was recommended the use of herbal blends, oils, Ayurvedic diet, and lifestyle changes. This was done in gradual phases and lasted for about six months. The American College of Rheumatology’s Arthritis Impact Measurement Scales were used for pre and post assessment. Post Ayurvedic management, the client’s situation is greatly improved after Ayurvedic management and she still follows ayurvedic recommendations for maintenance. This case study provides positive insights and alternatives into the management of Arthritis.
Amazonite (A Microcline Feldspar) - An Anti-Cancerous Geo-Biotechnological Approach for H460: Human Lung Cancer with Validation via Ros Anti-Oxidant Analysis
(Mahadev Publications, 2024-05) Malhotra, Yamini; Subramanian, Singara; Mohiuddin, Ishfaq; Selvaraj, Venkatesan; A, Ajin Bejino; A, Bobby Jones
The research delves into the medicinal properties of amazonite, with a particular focus on its potential application in nanomedicine for combating lung cancer. Employing the MTT Assay, the authors observed amazonite's impact on H460 lung cancer cells, revealing its cytotoxic effects and thereby suggesting its promise as an anti-cancer agent. Moreover, through ROS antioxidant analysis, the study unveiled amazonite's ability to regulate reactive oxygen species levels, indicating its potential in mitigating oxidative stress-induced damage, a hallmark of cancer progression. FTIR spectroscopy emerged as a crucial tool in the research, offering insights into amazonite's molecular composition and its possible interactions with biological molecules. Of paramount importance is the toxicity analysis conducted in the study, which revealed amazonite's low toxicity profile. This aspect is particularly significant as it underscores the safety of amazonite for potential therapeutic applications, including in conjunction with treatments like radiotherapy. The assurance of low toxicity is pivotal in ensuring the viability of amazonite as a candidate for clinical use, instilling confidence in its safety profile and minimizing adverse effects on patients. Overall, the findings of the research underscore amazonite's potential as a safe and effective nanomedicine for the treatment of lung cancer. The observed cytotoxic effects on cancer cells, coupled with its ability to modulate reactive oxygen species levels and low toxicity profile, position amazonite as a promising candidate for further exploration in the realm of cancer therapy. However, the study also highlights the need for continued research to fully elucidate the underlying mechanisms of amazonite's action and to explore its potential clinical applications comprehensively.
An An Enumerative Study On Garbha-avkranti From Susruta-sharira Wsr To Langman’s Medical Embryology
(Mahadev Publications, 2019-06) Sharma, Giriraj G; Sharma, Pooja
The Garbhaavkarnti is the stage that describes the process of the growth of cell from intra-uterine life to post natal stage. The Garbhaavkranti mainly deals with the pre-natal life i.e. the foetal period and other related processes. This period is minutely envisioned by Langman’s medical embryology, and in Susurta Sharira we have got more detailed version of pre-natal period. The Garbha-avkranti word signifies the Garbh i.e. zygote and Avkranti or Avatarana i.e. different stages of development of zygote. Garbhaavkranti is a process in which different stages of formation of Garbha is mentioned. Garbha (zygote) is formed from the uniparental inherent cells known as sperm and ovum. There are some special characteristics that combine or fuse together along with 24 other Gunas like Avyakta, Mahana, Ahankara, Prakriti Tatva and Bhava i.e. gene and chromosomes. There is no single way that may lead to the formation of Garbha. Matraja Bhava (maternal inheritance factor) is present in Aartava which further shows the quality of Aagnaya feature i.e. the mitochondria of ovum. The importance of embryology at that time was known by Susruta & the criteria for good progeny & the process by which embryo develops was all known to them in subtle level. It is fascinating to conclude that they knew about all this without the technological advances which are available today. The importance of healthy mother & father in phase of conception is shown in this Garbhavkranti. This gives the idea of unhealthy reasons and gives broad scale treatment for infertility cases. The Garbhaavkranti (embryology) is always a matter of mondo concern to medical field. So, in this article the Susurta Sharira Grabhavkranti is discussed precisely thereby referring to Langman’s medical embryology for testimonial based study.
Analogizing Of Metabolic Syndrome In Siddha System Of Medicine-a Literature Review
(Mahadev Publications, 2020-01) K, Samraj; P, Sathiyarajeswaran; S, Rajalakshmi; K, Nandhagopal; S, Radha; K, Arunachalam; K, Kanakavalli
Background: In worldwide, 20-25% of the population have the Metabolic Syndrome (MetS). The highest prevalence rate reported in South Asia of MetS in the Punjabi community in India by Adult Treatment Panel III criteria. The metabolic syndrome (MetS) is a major and escalating public-health and clinical challenge worldwide in the wake of rapid urbanization, surplus energy intake, increasing obesity, and sedentary life habits. Nowadays, the use of Complementary and Alternative Medicine (CAM) is increasing rapidly due to the inadequate solution for the newly developed health issues. Method: In this study, the International Diabetic Federation (IDF) criteria were used as a standard tool for comparison. A total of 9 sources (4 Siddha classical textbooks, e-data such as pub-med, Google scholar, AYUSH research portal, NAMSTP) were searched to identify the appropriate analog for MetS. Results: 13 Terms related to MetS were identified from the 4 Siddha classical literature, whereas the e-data did not provide any term related to MetS. In those 13 terms, 3 terms which were closely relevant to MetS signs and symptoms were Aiya Migu Kunam, Paci Aiya Noi, and Megam. As a final point, this paper identified the Siddha analog for MetS as Aiyamigukunam. Conclusion: This paper ended up with analog to MetS as Aiyamigukunam and made a comparison with the standard IDF criteria for MetS.
Analysis of Dyslipidemia as per Ayurveda and its Management
(Mahadev Publications, 2022-11) A, Hridya
Dyslipidaemias refers to any abnormality in the level of circulating plasma lipids. It is an extremely significant condition, majorly because of its contribution to atherogenesis. It is an independent and modifiable risk factor for CAD and stroke. More than half of global cases of ischemic heart disease are associated with dyslipidemia. Quality of care for dyslipidemia is suboptimal in general and variable by cardiovascular disease risk group, ethnicity and gender. In modern medicine, there are effective dyslipidemic drugs which give rapid relief, but may cause some long term side effects. So there is a need for safe alternative treatment which may be effective in reducing lipid level, for prolonged use. In Ayurveda, dyslipidemia can be considered as a condition in which Kapha, Medas and Rasa are pathologically deranged due to Ama. There is defective Medo dhatu poshana due to Dhatwagnimandhya and formation of Ama at the level of Medo dhatu. It can be considered as presumable level of stage of Samprapti or a morbid state which may cause disease, but not attained a full status of disease. Nidanas include Beejadushti, Ahara – vihara –vikara and Manasika nidanas. Lipid profile can be brought back to normal by correcting Agni and ensuring proper Dhatuparinama. Treatment modalities include Nidana parivarjana, Sodhana, Samana, Rasayana and following Pathyapathya. Drug having Kaphamedohara, Deepana, Pachana, Ruksha and Lekhana property is useful to treat this clinical condition.
Analysis Of Effect Of Amla Rasa (sour Food) In Different Concentrations On Mamsa Dhatu (muscle Tissue)
(Mahadev Publications, 2018-07) Kumar, Akshay; Kekuda, Prashanth; Kulkarni, Pratibha; M, Ravi; Bhat, Sudhakar
It is said that one should consume Shad-Rasayuktha Ahara for better nourishment. The nutritive value of the 6 Rasas (taste) has been explained in the classics of Ayurveda along with their harmful effects when used in excess. When Amla Rasa is taken in excess it produces Dantaharsha (Morbid sensation of teeth), Trishna (thirst) etc. Objectives - The present study is designed by administering Amla Rasa Pradhana Drvya given in different concentration 10% and 15% and effect on the Mamsa Dhatu is assessed by certain blood parameters. Material and Methods -Wistar strain albino rats of either sex, weighing of 200-300 g. Obtained from S.D.M Centre for Research in Ayurveda, Udupi, Karnataka. 5Groups were taken and Group 1 is Control, Group-2 is 15% Chincha, Group-3 is 15% Vrukshamla, Group-4 is 10% Chincha, Group-5 is 10% Vrukshamla which receives drug and laboratory food for 28days, next day blood was collected by supra-orbital puncture with the help of micro capillary tubes under mild ether anesthesia. Results - There was increase in the Total Protein, Serum Albumin and serum creatinine levels and decrease in Serum globulin, Serum Urea level and Body weight. Conclusion – the study suggests that there is catabolic action of the Amla Rasa on the Mamsa Dhatu and anabolic act action on serum protein especially at the level of liver, so there will be a loss of muscle tissue which suggests Mamsa Vidhahyati action.
Analytical Evaluation of Abhraka Bhasma Samples after Marana, Amritikarana and Lohitikarana
(Mahadev Publications, 2024-01) Varma, Arya S; Bhat, Satyanarayana; Nayak, Dinesh
Rasaushadhies or herbo-mineral formulations undergo rigorous processes to convert into nano size. The particle size does matters a lot in terms of absorption, assimilation and proper excretion from the body. The pharmaceutical procedures should be strictly adhered so as to ensure safety and efficacy. Abhraka bhasma is a popularly used formulation in Ayurvedic practice. Abhraka or black mica is a bad conductor of heat. So the process of Bhasmikarana requires high quantum of heat in order to render into Bhasma form. Amritikarana is a specific process included in the preparation of Abhraka bhasma. The current study evaluates the essentiality of this process in Bhasmikarana. A detailed analytical study is been carried out to find the differences in the samples before and after Amritikarana. The present study reveals that the particle size has reduced much and the iron content was at maximum concentration in the samples after the process of Amritikarana and Lohitikarana.
Analytical Profile of Kanchanara Guggulu Tablets Prepared as per References in Sharangadhara Samhita and Bhaishajya Ratnavali
(Mahadev Publications, 2022-07) Sunny, Sini Elizabeth; Lakshmi, S. Thara
Marketing of Guggulu, an exudate obtained from the plant Commiphora mukul and its preparations is a great concern of different ayurvedic pharmaceutical houses due to its adulteration, substitution and non-availability of genuine samples. Standardization of raw drugs and formulations with modern analytical tools increase their scope, acceptance and scientific validity. In the present study, an attempt was made for the physicochemical analysis of Kanchanara guggulu tablets (having Guggulu as the major ingredient) prepared as per references in Sharangadhara Samhita and Bhaishajya Ratnavali to develop an analytical profile of the formulation. The study was based on the standard analytical parameters proposed by API and PLIM. Six samples of tablets were prepared as per two references (three for each reference) which were available in market following the same manufacturing procedures. The study comprised of three stages- pharmacognosy of raw drugs, pharmaceutical work and analytical study. The analysis was done using the parameters like organoleptic evaluation, weight variation, hardness, friability, disintegration time, ash values, extractive values, loss on drying, pH, HPTLC and microbial contamination and an analytical profile was developed as per both references.

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