Indian Journal of Clinical Practice

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https://imsear.searo.who.int/handle/123456789/150289

Editor: Dr. KK Aggarwal
ISSN: 0971– 0876

Frequency: Monthly

Language: English

Open Access Peer-reviewed journal

Web site: https://www.ijcpgroup.com/

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Now showing 1 - 20 of 744

15 Ways to Reduce or Stop Drinking.
(2013-05) Aggarwal, K K
50 Ps to Know All About Dengue Fever.
(2013-11) Aggarwal, K K
Abnormal Thyroid Test Results in Euthyroid State: An Appraisal of the Role of Drugs
(IJCP Group, 2024-11) Krishnamurthy, Aishwarya; Bhattacharya, Saptarshi; Lathia, Tejal; Deka, Nilakshi
Background: Thyroid function tests (TFTs) are one of the most frequently performed hormonal tests. Abnormal reports are commonly encountered even in the absence of thyroid dysfunction. Concomitantly used medications are often implicated in this effect. Objectives: Failure to recognize drug-induced alterations in TFTs can result in misdiagnosis and inappropriate management. This review seeks to increase awareness of the common challenges and pitfalls encountered when interpreting drug-induced changes in TFTs. Methods: We did a literature search for eligible publications and articles published before April 2024 on drug-induced alterations in TFTs. Results: The common mechanisms by which drugs alter TFTs include assay interference and alterations in levels or affinity of thyroid-binding proteins (TBP). High-dose biotin can result in erroneous TFTs by interfering with immunoassays that utilize streptavidin-biotin immobilizing systems. The TFTs mimic findings seen in thyrotoxicosis after biotin intake. Heparin-induced increase in nonessential fatty acid causes displacement of thyroid hormone from TBP, resulting in an artefactual increase in free hormone levels. Increases or decreases in thyroid-binding globulin (TBG), the major TBP, cause concomitant changes in total thyroxine and triiodothyronine levels. Estrogen, selective estrogen receptor modulators (SERMs), 5-fluorouracil, mitotane, clofibrate, heroin, and methadone increase, while androgens, anabolic steroids, glucocorticoids, nicotinic acid, and L-asparaginase decrease TBG. Some medications like salicylates, frusemide, carbamazepine, and phenytoin displace thyroxine from TBP, producing a decline in the total hormone levels. Conclusion: Awareness about these drug-induced TFT fallacies is essential to avoid improper diagnosis and overtreatment.
ACCF/AHA Release Guideline for Early Cardiovascular Risk Assessment.
(2012-04) Indian Journal of Clinical Practice
Accidental PUVA Burns Leading to Prurigo Nodularis: A Rare Complication of Phototherapy.
(2013-07) Verma, Shyam
Medical treatment function vitiligo aims to restore color to use depigmented patches. Psoralen photochemotherapy (PUVA) may be used if there is extensive vitiligo. Possible long-term adverse effects of PUVA therapy include accelerated skin aging with wrinkle formation, telangiectasias, lentigines, elastosis, xerosis and pigmentary changes. Accidental burns during photochemotherapy have been reported though nodular prurigo has never been reported. Vitiliginous skin is more rone to burns.
ACCP Releases Statement on Dyspnea Treatment in Patients with Advanced Lung or Heart Disease.
(2012-06) Indian Journal of Clinical Practice
ACCP Releases Statement on Dyspnea Treatment in Patients with Advanced Lung or Heart Disease.
(2012-02) Indian Journal of Clinical Practice
Accuracy in Estimation of Gestational Age in Third Trimester by Fetal Kidney Length in Indian Women.
(2013-10) Gupta, D P; Gupta, Hem Prabha; Zaidi, Zeeshan; Saxena, D K; Gupta, Ratna Prabha
Introduction: Accuracy in estimation of gestational age (GA) has become more demanding as technology used in sonography has become more advanced. Patient’s expectations have also increased and they expect exact estimations to plan their pregnancies. Fetal kidney length (FKL) alone or in combination with other biometric indices can be used in estimating GA more precisely. Objective: The study aimed in measuring FKL and calculating GA using it as a single parameter and comparing the accuracy when combined with other biometric parameters used in estimation of GA on ultrasonography in third trimester in Indian women. Material and methods: Healthy pregnant women in third trimester with single live fetus with no maternal or fetal complications were selected for the study. FKL along with other biometric parameters were measured. The results were analyzed for finding if FKL could be used as a single parameter in estimation of GA and if the accuracy improved if combined with other indices. Results: GA was estimated in 715 cases by all four parameters in the women who came in the third trimester for ultrasonography. FKL was also measured simultaneously in these women. It was observed that average FKL increased linearly from 30.7 mm at 27 weeks to 39.4 mm at 38 weeks. Mean left kidney length was slightly but significantly more than the right kidney. GA was estimated by FKL alone and it gave results with SE ± 10.45 days and when combined with other indices accuracy improved to SE ± 5.45 days. Conclusion: FKL can be a single lone parameter in estimation of GA to give an accuracy of SE ± 10.45 days, but when used in combination with other four indices the accuracy increased to SE ± 5.5 days.
Accuracy, Precision, Sensitivity, and Patient Preferences of Accu-Chek® Self-Monitoring Blood Glucose Meters: A Targeted Literature Review
(IJCP Group, 2025-02) KALRA, SANJAY; KAPOOR, NITIN; SOORAGONDA, BASAVARAJ; SHUKLA, RISHI; SHEIKH, SHEHLA; CHANDRASEKARAN, SRUTI; SHINDE, SURESH N; UNNIKRISHNAN, AG; MAYOR, REGINA; PRESENTI, CATERINA; ROETSCHKE, JULIA; GALA, VISHAL; AUGUSTINE, ABIN
Self-monitoring of blood glucose (SMBG) using blood glucose monitoring (BGM) devices is recommended for people with diabetes to improve glycemic control and to detect and prevent episodes of hypoglycemia in these patients. The International Organization for Standardization (ISO) and World Health Organization (WHO) have defined specific criteria for accuracy, precision, user evaluation, and interfering agents for the quality of these devices. In this targeted literature review, Accu-Chek® devices (Instant®, Guide®, Active® ) were found to have stable results with appropriate accuracy and precision and did not respond to interfering agents. The devices were also found to be cost-effective and ranked high on patient preference.
Acid Throwing: A Cause of Concern in India.
(2014-03) Bhullar, D S
Acinic Cell Carcinoma of the Parotid.
(2013-12) Easweran, S V; Lokesh; Raghvendra, U; Yuvraj; Manjula
Acinic cell carcinoma, also known as acinar/acinous cell carcinoma is a rare salivary gland cancer (6-10%). Around 3-13% malignancies involve the parotid; it arises to also from other glands namely submandibular, minor salivary gland, rarely parapharyngeal spaces,1,2 pancreas and lung (which it, usually metastasizes). Acinic cell carcinoma usually occur bilaterally, it presents in younger median age. It is a slow growing, painless tumor. It affects females more than males. Facial nerve is spared. If it metastatizes, it does so to the lung, bone, CNS, mediastinum, liver and brain.
Acute Fatty Liver of Pregnancy.
(2013-02) Shah, Jitesh Mafatlal; Mehta, Meghana Narendrabhai; Viradiya, Hiral Babubhai
Acute fatty liver of pregnancy (AFLP) is a rare life-threatening complication of pregnancy. It usually occurs in late third trimester. There is usually severe liver dysfunction with hypofibrinogenemia, hypoalbuminemia, hypocholesterolemia and prolonged clotting times. The most critical component of caring for a woman with AFLP is the delivery of her fetus.
Acute Onset Hypokalemic Quadriparesis with Dengue Fever: A Case Report.
(2014-10) Kumar, Praveen; Chandra, Kalpana; Varshney, Amit
Dengue fever is an acute viral disease caused by dengue virus (DENV1- 4) and is endemic to India. It commonly presents as fever along with headache, bodyache, rashes, polyserositis, bleeding manifestations and rarely as cardiovascular, gastrointestinal, renal or neurological manifestations. Here, we report a case of dengue fever with hypokalemic quadriparesis. A 38-year-old male admitted with history of fever of 3-day duration and weakness of all four limbs of 1-day duration. His investigations showed Hb - 16.20 g/dL, platelet - 37,000/mm3, serum Na+ - 150.00 mmol/L, serum K+ - 2.50 mmol/L and positive dengue serology. Hypokalemic quadriparesis secondary to dengue fever should be considered as a differential diagnosis in a case of acute febrile illness with muscle weakness in tropical countries.
Acute Onset Vesicular Rash.
(2012-01) Indian Journal of Clinical Practice
Acute Pancreatitis in Pregnancy.
(2012-09) Sreelatha, S; Nayak, Vedavathy; Nataraj
Acute pancreatitis is a rare event in pregnancy, which can have a high maternal mortality and fetal loss. Gallstone disease is thought to be responsible for about 70% of these cases. We report a case of a 28-year-old woman, who presented with severe pain confined to the upper abdomen, which was radiating to the back. Investigation undertaken led to the diagnoses of acute pancreatitis.
Acute Renal Failure and Silent Myocardial Infarction Following Multiple Honey Bee Stings.
(2014-01) Fernandes, Kavina Marian; Srikant, R Gadwalkar; Shyamala, G
Massive envenomation by honey bee sting is capable of causing multiorgan dysfunction as a result of direct toxic effect of venom and secondary to systemic anaphylactic reactions. Myocardial infarction (MI) due to honey bee sting is rare, so is acute renal failure (ARF). The probable mechanism is severe coronary arterial spasm with secondary in situ thrombosis as a result of systemic anaphylaxis. This is a case of Kounis syndrome, which is the concurrence of acute coronary syndromes with conditions associated with mast cell activation. We describe a case of ARF and MI in a 58-year-old man after multiple honey bee stings; clinically silent and detected on electrocardiography and by cardiac biomarkers.
Addison Disease: Early Detection and Treatment Principles.
(2014-11) Michels, Aaron; Michels, Nicole
Primary adrenal insufficiency, or Addison disease, has many causes, the most common of which is autoimmune adrenalitis. Autoimmune adrenalitis results from destruction of the adrenal cortex, which leads to deficiencies in glucocorticoids, mineralocorticoids, and adrenal androgens. In the United States and Western Europe, the estimated prevalence of Addison disease is one in 20,000 persons; therefore, a high clinical suspicion is needed to avoid misdiagnosing a life-threatening adrenal crisis (i.e., shock, hypotension, and volume depletion). The clinical manifestations before an adrenal crisis are subtle and can include hyperpigmentation, fatigue, anorexia, orthostasis, nausea, muscle and joint pain, and salt craving. Cortisol levels decrease and adrenocorticotropic hormone levels increase. When clinically suspected, patients should undergo a cosyntropin stimulation test to confirm the diagnosis. Treatment of primary adrenal insufficiency requires replacement of mineralocorticoids and glucocorticoids. During times of stress (e.g., illness, invasive surgical procedures), stress-dose glucocorticoids are required because destruction of the adrenal glands prevents an adequate physiologic response. Management of primary adrenal insufficiency or autoimmune adrenalitis requires vigilance for concomitant autoimmune diseases; up to 50% of patients develop another autoimmune disorder during their lifetime.
Addressing Lower Segment Cesarean Section Hesitancy: A Patient-centered, Pragmatic Communication Guide
(IJCP Group, 2022-08) Kalra, Bharti; Sharma, Anjali; Dhingra, Kamlesh; Agrawal, Swati
In women in whom a normal vaginal delivery is not possible or is not indicated, delayed acceptance of lower segment cesarean section (LSCS) or outright LSCS refusal, leads to complications that can easily be avoided. Hence, it makes sense for obstetricians and other health care professionals, to address LSCS hesitancy as an integral part of obstetric care. In this article, we discuss both the communication style and communication content, that is required to manage LSCS hesitancy in women in whom the intervention is indicated. We highlight the need to analyze the reasons for hesitancy, and address them in an appropriate and affable manner, using accurate information to buttress one’s points. We also encourage seeking assistance from colleagues in the health care team, utilizing audio-visual and social media aids, and offering alternatives if the patient so desires.
Adolescent with a Diffuse, Progressive Rash.
(2012-02) Indian Journal of Clinical Practice
Adolescent with a Diffuse, Progressive Rash.
(2012-06) Indian Journal of Clinical Practice

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