Paripex - Indian Journal Of Research

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A-case-of-breast-myofibroblastoma—a-rare-diagnosis-on-histopathology
(Indian Society for Health and Advanced Research, 2023-05) Baria, Mitalkumari; Raval, Nisha
INTRODUCTION: Myofibroblastoma is a benign mesenchymal tumor originally described in the male breast but also occurring in the female breast. CASE REPORT: A 15 years old male present in surgery department with complain of left breast lump since 10 days. It was non tender and mobile. USG: Subcutaneous swelling. FNAC: fibrofatty tissue. DISCUSSION: Myofibroblastoma is a benign mesenchymal tumor originally described in the male breast but also occurring in the female breast.
A-case-report-of-rare-disease-acrocallosal-syndrome
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-10) Bellamkondi, Megha; Bandichhode, Sachin; Chakre, Sudarshan; More, Suraj
Acrocallosal syndrome (ACS)1,2 is characterised by post-axial polydactyly, duplication of the hallux, and abnormality of corpus callosum including agenesis or dysgenesis, occasional anencephaly, and/or Dandy朩alker malformation, characteristic craniofacial abnormalities, and moderate-to-severe mental retardation. One year old male child admitted in view of convulsions who has dysmorphicfacies, polydactyly, Hallux duplication, undescended testis. MRI brain showed carpus callosal agenesis and Whole exon sequencing � KIF 7 gene mutation. Acrocallosal syndrome is rare with only a limited number of cases being described in the literature. Early recognition of the condition is necessary to intervene surgically and to counsel the parents regarding the genetics of the disease and dedicated follow-up of the affected child in special OPDs. Molecular testing should be done in all suspected cases.
A-case-report-of-zellweger-syndrome-with-global-deveopmental-delay
(Indian Society for Health and Advanced Research, 2023-02) Ghodasara, Riya; Shah, Hiral; Bhatt, Richa
Peroxisome biogenesis disorder are related to spectrum of genetic diseases that range from severe Zellweger syndrome to milder infantile Refsum disease. Zellweger syndrome is characterized by dysmorphic features, severe hypotonia, seizures, failure to thrive, liver dysfunction and skeletal defects. We report a case of Zellweger syndrome, confirmed by clinical, biochemical and molecular findings, diagnosed in context of dysmorphism, and seizures.
A-prospective-study-comparing-the-outcomes-of-nasal-septal-clip-versus-merocel-application-after-nasal-septal-corrective-surgery
(Indian Society for Health and Advanced Research, 2023-03) Bora, Kum Kum; Ahmed, Mohammed Izaz
Nasal splint application is an important step of septal corrective surgeries to keep the septum in midline after the surgery. Septal clip is most commonly used. In our study we have compared the use of nasal septal clip and Merocel application post surgery and the morbidities associated with it.
A-prospective-study-of-role-of-bacteria-in-gall-stone-disease
(Indian Society for Health and Advanced Research, 2023-03) Varale, Kirti B.; Rb, Naziya; Majeed, Abdul
Aim: To know organism most commonly found in bile, to study and compare the incidence of gall stone in culture negative versus culture positive bile. bile will be collected from removed gall bladder after the patientMethod: undergoes cholecystectomy and subjected to culture and sensitivity, and the result of the organism found will be tabulated and incidence of which organism is highest will be known in the study and which antibiotic was it most sensitive to will be noted. A total of 29 patients were included in the study. Out of 29 calculous cholelithiasisResults: patients only 10 of them had positive bile culture. More than 50 percent of patients had growth belonging to the Enterobacter family, and highest sensitivity was for imipenem antibiotic.
A-rare-case-of-bilateral-ovarian-fibroma-arising-from-ovarian-stroma-histopathology-case-report
(Indian Society for Health and Advanced Research, 2023-01) Kachrola, Poonam R.; Mori, Neelam K.
INTRODUCTION: Ovarian fibroma is a solid tumor that belongs to sex-cord stromal cell tumor of ovary commonest benign tumor of ovarian stroma. A 43-year-old female admitted in obstetric and gynecologyCASE REPORT: department with complain of abdominal pain for 2 months and heavy menses. Ovarian fibroma areDISCUSSION: common benign ovarian tumor accounts for approximately 1-4% of ovarian tumor usually unilateral but bilateral ovarian fibroma is rare entity. Large ovarian fibroma can be associated with ascites and right sided pleural effusion (Meigs syndrome)
A-retrospective-study-on-maternal-mortality-in-a-tertiary-care-setup-2year-review-during-covid-pandemic
(Indian Society for Health and Advanced Research, 2023-01) Nisha, Korimilli; Keerthana, M. N. V.; Jayanthi, P.
Introduction: Epidemiological data related to maternal mortality is valuable in each setup to design interventional programs to reduce the ratio favorably. This study was done to evaluate the maternal mortality rate in our hospital GGH GUNTUR from January 2020 to December 2021, to assess the epidemiological aspects and causes of maternal mortality, and to suggest recommendations for improvement. Objectives: 1. To estimate the maternal mortality rate in GGH Guntur 2. To identify the causes associated with maternal mortality 3. To identify epidemiological risk factors for maternal mortality 4. To recommend ideas for reducing MMR to prevent maternal deaths. Methods: This is a 2-year retrospective study conducted in our hospital, GGH Guntur, Andhra Pradesh. All data presented were collected from hospital records and the causes were assessed, some of the epidemiological risk factors were identified, and maternal mortality rates were calculated. A total of 165 maternal deaths occurred. Most maternal deathsResults: occurred in the age group of 20–24 years, primi women (53.33%), women from rural areas (75.15%), and unbooked patients (95.15%). Direct causes accounted for 52.27% of maternal deaths, 28.48% of maternal deaths were due to indirect causes and 17.57% of maternal deaths were due to non-obstetric causes ( 89.65 % were due to covid-19) Conclusion: Better reporting of maternal deaths and implementation of evidence-based, focused strategies, along with effective monitoring of maternal health, emphasizes the need for regulation of the private sector and encourages further public-private partnerships and policies, as well as a robust political will and enhanced management capacity for improving maternal health, particularly in an unprecedented health crisis such as Covid-19. As a considerable number of the recorded deaths are preventable, there is substantial room for advancement.
A-review-the-elderly-patients-in-dentistry
(Indian Society for Health and Advanced Research, 2023-05) Kaplan, Mehmet; Discioglu, Feridun
The aim of this review is to determine the factors that cause oral and dental health problems in the elderly. Maintenance of a natural, healthy and functional dentition is as important for healthy aging as maintaining physical and mental abilities. Over the past century, scientific progress has significantly increased life expectancy, people's living standards are improving and people are paying more attention to hygiene conditions. The role of oral and dental health on the general health status of the elderly population is too great to be ignored. In a number of cases, in addition to the effects of Aging on the orofacial region, acquired systemic diseases and the medications used in their treatment cause unpleasant changes in the oral cavity. Tooth loss, abrasions, periodontal diseases, dental caries, lesions in the oral mucosa, etc. cause elderly patients to be unable to perform oral functions well enough. Speech difficulties, muscle atrophy and changes in taste can also be observed. Elderly people need to be treated in cooperation with medical doctors and dentists who monitor the general health of the elderly and ensure good dental care
A-study-of-association-of-first-trimester-serum-uric-acid-levels-with-development-of-gestational-diabetes-mellitus
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-09) Monisha, Devi V J; Sudharani, A; Mamatha, Paleti
Objectives: GDM is a major pregnancy complication that can cause maternal and foetal morbidity and mortality . A substantial amount of research suggests that uric acid may be a major risk factor for the development of diabetes in women. The purpose of this research was to determine whether early pregnancy maternal blood uric acid levels and the onset of gestational diabetes mellitus are interrelated. The prospective observational study was conducted inMethods: Government general hospital, Kurnool from November 2023 to May 2024. Pregnant women of gestational age up to 13 weeks who visited the OBG outpatient department for regular antenatal check-ups during this time period were enrolled in the study with prior consent. In our study, among the 360 pregnant women, 43 (12%) developed GDM.Result: Of these Women with GDM 34 (79.07%) had uric acid levels above 3.5 mg/dl and 9 women (20.93%) with GDM had uric acid levels below 3.5 mg/dl. In present study, the serum Uric acid levels with the criteria of >3.5mg/dl , demonstrated that sensitivity of 80.95% and specificity of 97.16%. There is a strong association between the onset of GDMConclusion: and an elevated serum uric acid level during the first trimester. A 3.5 mg/dl cut-off level appears to have good sensitivity and specificity.
A-study-of-prevalence-on-maternal-mortality-in-covid19
(Indian Society for Health and Advanced Research, 2023-03) Keerthi, Gudipalli; Unnisa, Naseer
Introduction On march 11, 2020, WHO officially announced that COVID 19 has become global pandemic . Most of the studies available on COVID 19 have evaluated the impact of the disease in general population and there are insufficient data on COVID 19 in pregnancy. Pregnant women are more susceptible to acquired viral respiratory infection and severe pneumonia due to physiological changes in immune and cardiopulmonary system during pregnancy COVID 19 infection in pregnancy more likely present as mild symptomatic infection or it may be asymptomatic and the risk of COVID 19 infection for pregnant women may be SARS or middle east respiratory syndrome. Aims And Objectives Aim: ObjectiveTO audit maternal mortality due to COVID 19 : To estimate the prevalence of maternal mortality due to COVID 19 infection in obstetrics patients. A cross sectional study was conducted fromMaterials And Methodology January 1st 2020 to May 30 2022 at GOVERNMENT GENERAL HOSPITAL ,GUNTUR, a tertiary care centre. During study period all pregnant women and antenatal, intrapartum and postpartum who were diagnosed to have COVID 19 infection by RTPCR or RAPID ANTIGEN TEST positive were considered. Out of 942 cases of COVID 19 recordedResults throughout the study period, the prevelance of maternal mortality is 3.3% (32 cases) According to age wise distribution, 37.5% in 20-25 years age group, 56.25% in 25-30 years age group, 6.2% in 30-35years age group. According to BMI 15.6% deaths in 18.5 -24.9, 59.3% deaths in 25-29.9 group, 25% deaths in 30-34.9 group. According to socioeconomic status 50% in lower SCS, 40.6% in lower middle class group, 9.3% in upper middle class group According to gestational age wise distribution 28% in 24-30 weeks of GA, 46.8% in 32-36 weeks of GA , 25% in 35 and above and postpartum. According to CT severity score number of deaths are 90.6% if score greater than 16, 9.3% with score of 8-15, 0% with score of less than 7. Based on investigations D-dimer elevated in 100% of death cases, serum ferritin elevated in 68.7% of death cases , CRP elevated in 93.7% of death cases
A-study-on-consumer-buying-behaviour-of-fast-moving-consumer-goods-in-rural-market
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-08) Poornima, S.
Today the FMCG sector is enjoying a vital role within the Indian economy. 'Go rural' is that the motto of marketing gurus when analyzing the socioeconomic changes in villages. Rural marketing has been growing steadily over the years and is currently larger than the urban marketplace for FMCGs. The aim of this research work analyzes the demographic variables of consumer buying behaviour factors towards FMCG brands in the rural market in Mysuru District of Karnataka. The sampling technique used for this analysis study was the convenient sampling technique. For the aim of the study 168 respondents are chosen within the Mysuru district. The survey has utilized both primary data and secondary data. The tools used to analyze the data are Simple percentage analysis, 't' test, and ANOVA. This paper reveals that consumer behaviour is largely affected by cultural and social factors, personal factors than psychological factors.
A-study-on-consumer-buying-behaviour-towards-departmental-stores-with-special-reference-to-imphal-city
(Indian Society for Health and Advanced Research, 2023-03) Singh, Telem Abungcha; Aimol, Khoichung Rangamlian; Singh, Puyam Dholendro
This study explores consumer buying behavior towards departmental stores in Imphal city, aiming to help retailers better understand and capture their target consumers. The research type is qualitative in nature, as the aim was to uncover underlying consumer motivations regarding departmental stores in the Imphal area of Manipur. A sample of 105 respondents was analyzed using statistical tools including percentage analysis, rank analysis, and Likert scale. The results indicate that consumers prefer stores offering a variety of quality-maintained products, with discounts and special offers also playing a significant role in attracting customers. This study underscores the importance of continued analysis and assessment of consumer behavior and satisfaction in ensuring the long-term success of businesses
A-study-on-improved-patient-outcomes-in-septic-shock-with-use-of-hydrocortisone
(Indian Society for Health and Advanced Research, 2023-01) Desai, Viraj; Mehta, Prashant. V.; Rs, Anusha; Mali, Paresh
Management of sepsis is a time critical procedure; the consequences of improperly managed sepsis and septic shock can cause multiple organ dysfunction and death. The aim of this study was to evaluate of the role of hydrocortisone. Ÿ Sepsis is dened as life-threatening condition causing multi-organ dysfunction by a dysregulated host response to infection. Septic shock is a subset of sepsis with circulatory and cellular or metabolic dysfunction associated with a higher risk of mortality . Ÿ Sepsis is said to effect the hypothalamic pituitary adrenal axis, causing a relative adrenal insufficiency resulting in cardiovascular instability, metabolic disorders, and a sustained pro- inammatory state. Ÿ The role of pro-inammatory pathways suggests a potential use for corticosteroids as an adjuvant therapy in the treatment of sepsis and septic shock . The Surviving Sepsis campaign guidelines recommend that if adequate uid resuscitation and vasopressors have not restored the hemodynamic stability, it was postulated in limited data to use inj hydrocortisone 100mg i/v 8 hourly for 7 days . Ÿ There was an improvement in the overall survival and reduction in the mortality and morbidity of patients, as observed by early weaning off from vasopressor support, reduction in total leucocyte counts and
A-study-on-management-of-bleeding-haemorrhoids-with-calcium-dobesilate-vs-inj-sclerotherapy
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-07) Punekar, Meher Darakshan; Awati, Jilani S; Pasha, Iram T
Introduction: Hemorrhoids are very common anorectal conditions that should be treated as early as possible. The treatment options are surgery, injection sclerotherapy, rubber band ligation, conservative management with flavonoids,calcium dobesilate,diet modificatons. A prospective study was done at Amch Vijayapura.Materials: Detailed clinical examination was done, diagnosis of hemorrhoids were made.A total of 100 patients with grade 1 and 2 haemorrhoids with active bleeding were selected for the study and divided into 2 groups. Group A 50 patients treated with calcium dobesilate and Group B 50 patients with injection sclerotherapy.The patients were followed up at 2 weeks, and 1,6,9 month in terms of improvement in symptoms and any complications. This study demonstrated thatResults: both calcium dobesilate and injection sclerotherapy had improved per rectal bleeding after 3 and 6 weeks of treatment, but injection sclerotherapy had better outcome over calcium dobesilate after 6 months of treatment (54% vs. 36%). In case of reduction of hemorrhoidal mass � injection sclerotherapy had significantly better outcome in all the follow-up visits, that is, 3 weeks (52% vs. 18%), 6 weeks (64% vs. 30%) and 6 months (60% vs. 28%). Injection sclerotherapy had superior overall treatment outcome after 6 weeks of treatment (66% vs. 42%) and long-term periods (56% vs. 28%). Conclusion: Injection sclerotherapy has been found to offer lasting benefits for the treatment of symptomatic hemorrhoids, unlike calcium dobesilate, which usually offers only temporary relief for per rectal bleeding. This means that while injection sclerotherapy leads to sustained improvement in symptoms, conservative management with calcium dobesilate tends to provide short-term relief specifically for bleeding per rectum.
A-study-on-online-shopping-behaviour-with-special-reference-to-alappuzha-district
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-10) S, Mahima; Gopalakrishanan, Sreedevi; B, Deepthi; A, Alfiya
Online shopping is a recent phenomenon in the field of e-business. The rise in the number of households possessing smart phones with high-speed internet access has led to widespread acceptance of e-commerce. The competition among e-vendors is getting intensified year by year, and all of them are adopting innovative and creative approaches to attract, satisfy, and retain customers. Accessibility and convenience are the key drivers for a major shift to online shopping. Due to ever increasing work pressure, multiple roles in life style, paucity of time, etc., consumers are on the lookout for such facilities that can suit their changing needs. The present study is an attempt to make an inquiry into the factors that determine the online buying behavior and suggestions to improve the online shopping experience.
A-study-on-placental-and-umbilical-cord-morphology-in-mothers-with-preeclampsia-and-its-correlation-with-foetal-outcome-at-birth-in-a-tertiary-care-hospital
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-09) Sinha, Sweta; Kumar, Pravin; Chattopadhyay, Nibedita; Sengupta, Mini
Introduction: The placenta is a distinctive characteristic of higher mammals which is attached to the uterus and is connected to the foetus through the umbilical cord. The placenta is an organ of vital importance for the continuation of a pregnancy and foetal nutrition. In humans, after the birth of the infant, placenta is often disposed soon after parturition without adequate examination. It has been seen that many disorders of the pregnancy are associated with gross anatomical, physiological, and pathological changes in the placenta. Hypertension is one of the common complications met with in pregnancy and contributes significantly to maternal and perinatal morbidity and mortality. Of the few studies that have explored the subject, it has been seen that morphologically, the placentae of hypertensive disorders of pregnancy are smaller, with lesser weight, diameter, and thickness as compared to placentae of normal women. Even fewer studies have been done which have correlated these altered placental findings with foetal and neonatal outcomes. Objective: Here we did a study on placental and umbilical cord morphology in mothers with pre-eclampsia and its correlation with foetal outcome at birth in a tertiary care hospital. The study populationMaterial And Methods: consisted of women of gestational age >34 weeks with diagnosed pregnancy induced hypertension or pre-eclampsia who were admitted to the labour room of the study institution for delivery. Mothers with hypertensiveConclusion: disorders of pregnancy tend to have a high incidence of abnormal placental and umbilical cord morphology at delivery such as lower placental weight, diameter, thickness, lower umbilical cord weight, diameter, and length.
A-study-to-assess-the-level-of-risk-for-hypertension-among-nursing-officers-working-in-esic-medical-college-and-hospital-kalaburgi-karnataka
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-10) V R, Balarama; Hunashyal, Ganesh C
Hypertension is a serious disease with increasing worldwide prevalence leading to life threatening complication. Hypertension, a major public health concern, affects over 1.28 billion people globally. The worldwide prevalence of hypertension in adults is estimated to be around 30-40%. In India, the prevalence is about 29.8%, with increasing rates in both urban and rural populations. Since the nursing officials are the backbone of any health care system, the researchers felt that the nursing officials go through tedious or hard work pattern; they also felt that it would be beneficial to know their risk of developing hypertension among them. to assess the level of risk of hypertension among theObjectives: nursing officers and to find the association between the level of risk for hypertension and selected demographic variables. A non evaluative descriptive research approach was adapted to collect the data, by the SelfMethodology: Administered hypertension risk assessment tool. The conveniently selected sample of 60 Nursing officers working in ESIC Medical College and hospital, Kalaburgi, Karnataka. The major findings of the study showed that theResults: overall Mean percentage was found to be 55.73% and the overall Mean Score for. hypertension risk score was 26.75� SD. And Majority i.e 73.33% of the Nursing officials are at Moderate risk for hypertension. It can be concluded that Nursing officers working in ESIC Medical College and hospital Kalaburgi comes under moderate risk for hypertension, where risk reduction educational interventions to be implemented and evaluated
Abhinaya In Upendra Bhanja's Literature
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-04) Biswajeeta, Bidya; Mohapatra, Ratikant
This paper delves into the profound influence of Upendra Bhanja on Odia literature and Odissi dance. Bhanja's poetic compositions, renowned for their musicality and emotive depth, serve as pillars of Odia literary tradition, reflecting the essence of classical Indian culture. Particularly, his works resonate within the Abhinaya aspects of Odissi dance, offering rich thematic material for performers. Through poems like "Koti Bramhanda Sundari" and "Baidehisa Bilasa," Bhanja's exploration of Sringara Rasa evokes timeless themes of love and devotion, akin to Jayadeva's Geeta Govinda. His literary craftsmanship, comparable to classical Sanskrit works, has earned him widespread acclaim. Moreover, Bhanja's interdisciplinary influence extends beyond literature, enriching various art forms. As a result, his legacy persists as a cornerstone of Odia cultural heritage, inspiring creativity and resonating with audiences across generations.
Abnormal vaginal discharge in reproductive age group women with special implication to antifungal susceptibility of candida species
(Indian Society for Health and Advanced Research, 2022-08) Anuradha, C.; Rama, Ch.; Sreevani, P.
Introduction And Background: Vaginal discharge is a common complaint in reproductive age group women2. Vaginal discharge is one of the common reasons in women of reproductive age group seeking gynecological consultation. It is the second most common clinical problem after menstrual disorders. Globally, it is estimated that one in ten women will present with vaginal discharge in the course of one year and approximately, ten million office visits each year are attributed to vaginal discharge complaints. The prevalence of vaginal discharge in India is estimated to be 30%3. Ÿ Abnormal vaginal discharge predisposes to significant morbidity to the women in the form of pelvic inflammatory disease, infertility, endometriosis, cuff cellulitis, urethral syndrome, pregnancy loss, and preterm labour.5 Ÿ Certain conditions such as prolonged use of combined oral contraceptive, pregnancy, malnutrition, diabetes, neutropenia, prolonged antibiotic therapy, candida become pathogenic and causes candidiasis.8 Ÿ Isolation, identification, characterization, and susceptibility of candida species became critical management of fungal infections.9 Need For The Study: The study was done to emphasize the role of laboratory investigations in patients with vaginitis, as presumptive clinical diagnosis alone can lead to false interpretation and treatment mismanagement. TheMethods: present study is a cross sectional observational study conducted from January 2019 to February 2020 for about a period of one year among 300 women aged 15-49 years with vaginal discharge attending gynecology OPD, Government Maternity Hospital, Tirupati. This study included 300 subjects with a mean age of 30.4 ± 7.26 years. Nearly halfResults: of (49.33%) our study population was aged between 25 to 34years, a majority (47%) of women had bacterial vaginosis, followed by Candida in 39.33%, trichomonas vaginalis in 14.33%, mixed infections in 6.67% and 6% with no organisms. Among Candida species, 48.31% of participants had candida albicans, 23.73% had candida tropicalis, 19.49% had candida krusei, and 8.47% had candida glabrata, and of them 38.33% participants had voriconazole sensitivity, 32.33% participants had ketoconazole sensitivity, 26% participants had clotrimazole sensitivity, and 21.33% participants had fluconazole sensitivity. Among 118 candida infected 106 (89.83%) participants came for follow-up, of which symptoms subsided in 90 (84.91%) participants. In conclusion, our study with 300 women patients complaining ofConclusion: vaginal discharge found a majority of them belonging to the sexually active age group. Vaginal discharge was more prevalent in lower economic status and rural areas. Bacterial vaginosis was the most common and frequent etiology, followed by Candida. TV was the least common etiology for vaginal discharge
Abrogation Of Article 370: A Critical Analysis
(INDIAN SOCIETY FOR HEALTH AND ADVANCED RESEARCH, 2024-10) Barki, Shreedhar
The abrogation of Article 370 on August 5, 2019, represents a significant shift in the political landscape of India and its relationship with Jammu and Kashmir (J&K). This article critically examines the historical context, legal implications, political ramifications, social consequences, and international responses to the abrogation. It aims to provide a comprehensive understanding of how this move has transformed the governance structure of J&K and its implications for Indian federalism, national integration and regional stability. The decision to abrogate this article had profound political, social and legal ramifications. Hence, this research article explores the impact of the abrogation on Indian politics by addressing the some key issues.

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