International Journal of Medical Research Professionals
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Editor-in-Chief: Dr. Rohin Garg
ISSN: 2454-6356 (Print); 2454-6364 (Online)
Frequency: Bimonthly
Language: English
Open Access Peer-reviewed journal
Web site: https://ijmrp.com/Default.aspx
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Item Spectrum of Microorganisms Causing Blood Stream Infection and the Antibiotic Sensitivity Pattern among Gram Negative Organisms: A Study from a Tertiary Care Centre in Bihar(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Kumar, Chandan; Kumar, Saurav; Kumar, Sunil; Mahto, H.LIntroduction: Incidence of Blood stream infection (BSI) is onthe rise and so is the increasing drug resistance amongdifferent organisms causing BSI. The trend of such infectionand the antibiotic sensitivity pattern may vary from region toregion.Materials and Methods: This study was conducted with thesame aim in which about 240 blood culture and sensitivityresults were noted from the records and were analysed to seethe current trend in this region. Our focus was mainly on Gramnegative organisms, as they have been found to causeincreased number of BSI.Results: Escherichia coli was the main Gram negativeorganism, and Staphylococcus aureus along with Coagulasenegative Staphylococcus (CoNS) were the main gram positiveorganisms isolated. Candida albicans was also found in four ofthe cases. The antibiotic sensitivity pattern of gram negativeisolates showed more than 90% susceptibility to higherantibiotics, whereas the susceptibility to other antibiotics werefound to be variable.Conclusion: E. coli is the main GNB causing the infectionfollowed by K. pneumoniae and P. aeruginosa. Increasingtrend of drug resistance is being noted by GNBs against mostcommonly used antibiotics.Item Necrotizing Soft Tissue Infections: Management and Outcomes in a Tertiary Care Hospital of North India(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Kumar, Ashutosh; Shahab, Saqib; Bhat, Shahnawaz BashirIntroduction: Necrotizing soft tissue infections (NSTIs) are agroup of fulminant infections which can involve any part of thesoft tissue with high mortality rate. Hence, it requires promptrecognition and management consisting of critical care supportand widespread surgical debridement.Methods: The present study summarizes the epidemiology,clinical features, risk factors and treatment principles used tomanage cases of NSTIs in a Tertiary care hospital of Delhi.Results: NSTI was found to be more prevalent in males(72.06%), 66.17% of the cases were those who were alreadysuffering from comorbidities. A high mortality rate of 20.59%was observed in the study.Conclusion: Diagnosis is deciding factor for overall positiveoutcome in these cases, which is usually made on the basis ofclinical history, physical findings and high index of suspicion.Overall management needs a multidisciplinary approach.Item Surgical Outcome of Elderly Patients Having Cervical Spondylotic Myelopathy: A Comparative Study Using JOA Scoring(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Rahman, Md Moshiur; Khan, S.I.M. KhairunNabi; Khan, Robert Ahmed; Islam, Md Rokibul; Ahmed, FaridBackground: Surgical outcome in patients with cervicalspondylotic myelopathy may affects by variety of factors.Different study outcome suggest that the number of symptomsand involved levels, symptom duration and posterior approachsignificantly increased with increasing age, whereaspreoperative Japanese Orthopedic Association scoredecreased among the different age groups.Objective: The goal of this study is to analyze the surgicaloutcome by comparing younger and elderly patient groups onthe basis of preoperative radiological and clinical data.Methods: To find out the surgical outcome the clinical andradiological data of 32 patients who underwent expansivelaminoplasty were reviewed after their surgery had beenperformed. All of the Patients were divided into two groups,group (a): younger patient group (<65 yr of age; n = 13) andan elderly patient group (≥65 yr of age; n = 19). Patients wereassessed by use of the Japanese Orthopaedic Associationscale (JOA) to know the neurological status of them. Computedtomographic myelography and magnetic resonance imagingexamined for radiological feature. Finally, the effects of theclinical and radio-logical findings on neurological outcome wereinvestigated.Results: The scores of preoperative and postoperative meanof (JOA) in elderly patients were significantly lower thanyounger patients. In the elderly patients cases, the transversearea of the spinal cord at the level of maximum compressionand symptom duration were the factors that predicted anexcellent recovery on the other hand the transverse area wasthe only predictor of excellent recovery in younger patients.Intensity change on the spinal cord and age, preoperativeJapanese Orthopaedic Association score, canal diameter werenot predictive in either age range.Conclusion: Both younger and elderly patient groups thetransverse area of the spinal cord may be a reliable predictor ofexcellent recovery. In case of elderly patients shorter symptomduration was an important factor in the excellent recovery.Item Post Rhinoplasty Quality of Life and Satisfaction Rate: Literature Review(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) BinSaleh, Yara Mahdi; Alherabi, Jawaher Ali; Alhumaid, Lama Hameed; Alrasheed, Reem Saleh; Alkhowaiter, Rufaydah AliCosmetic surgeons and teenagers can benefit from anunderstanding about how psychological dispositions affect theoutcome of a plastic surgery. The influence of postoperativeself-consciousness of the body and its impact can helpsurgeons determine the satisfaction rate on their work, and thepatient’s quality of life. There is no method of determining thelevel of satisfaction that is free from bias, even the mostobjective quantitative method of analysis. An extensiveliterature search was conducted using search engines such asPubMed, Embase and Google scholar focusing onadolescents, who underwent rhinoplasty for cosmetic purposesand compared satisfaction levels reported through differentdemographic characteristics. It was clear that satisfactionlevels and outcomes such as depression differed by gender.Even boys are equally satisfied as girls; they seem to benefitless from rhinoplasty in their day-to-day life. However, therewere no clear reports that compared these factors amongstraces and weight of adolescents. Adolescents seekingthe rhinoplasty procedure have more distress linked withconsciousness of body image. Their level of satisfaction andquality of life can soar from a well-executed surgical procedure.Rhinoplasty can achieve a significant enhancement in thequality of life for the adolescents.Item Effect of Abnormal Levels of Serum Calcium Along With Lipids on Risk of Myocardial Infarction(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Chowdhury, Sanjeela N; Kabir, Fahmida; Chowdhury, Amirul H; Haque, Sheikh Anisul; Mazumder, Pinke; Haque, KMGIntroduction: An association involving increased serumcalcium and deviation of blood lipid profiles is suggested byresearch workers but any connection of this association withrisks of increased acute myocardial infarction (AMI) is not yetstated. We wish to look at the association of abnormal serumcalcium and lipid levels with occurrence of myocardialinfarction.Methods: A prospective case-control study consists of 50 AMIpatients were diagnosed by cardiologists and 50 apparentlyhealthy individuals entered in the study. Serum calcium, bloodlipid profiles, and anthropometric parameters were assessed inthese study individuals. Student’s t-test was used to comparedifferent values between patients and healthy individuals.Pearson’s correlation coefficient was also used to determinethe positive association between serum calcium, blood lipidprofiles in this study population.Results: Levels of serum calcium and blood lipid profiles inAMI patients were observed significantly higher than healthyindividuals. Furthermore, serum calcium levels showed positivecorrelation with serum cholesterol levels in AMI patients.Conclusions: These findings conclude that increased serumcalcium and abnormal lipid profiles May perhaps a link withincreased risk of AMI.Item A Study to Know the Effect of Antiepileptic Drugs on Liver Enzymes(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Jain, Manoj Kumar; Verma, Umesh KumarObjective: To know the effect of antiepileptic drugs on liverenzymes.Study Design: Cross sectional study.Materials & Methods: The study was conducted on 108patients at SIMS Hapur and G.S Medical College Hapurbetween Jan 17 to Dec 17. Patients divided into 3 groups,consisting of 36 patients in each group of phenytoin,carbamazepine and valproate.Results: Total No. of Patients was 108, out of which 36patients were there is each group of Phenytoin,Carbamazepine and valproate. Most of the patients 36(33.33%) and 32 (29.62%) belongs to age group of >40 – 50years and >50 year respectively. Regarding raised SGPT, itwas seen in 5 (13.89), 3 (8.33) and 3 (8.33) in phenytoin,carbamazepine and sodium valproate group respectively.SGOT were raised in sodium valproate group respectively.Alkaline phosphatase were raised in 10 (27.78), 20 (55.56) and22 (61.11) in phenytoin group, carbamazepine group, andsodium valproate group respectively.Conclusion: From the present study we can conclude thatsodium valproate is more hepatotoxic than carbamazepinewhich is more toxic than phenytoin. It is recommended thatbase line Liver Function Test (LFT) is essential before startingof AEDs and regular monitoring of LFT is also done betweenthe course of treatment.Item Snakebite: A Study on Clinical Presentation, Treatment and Public Awareness(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Saitya, Atul KumarIntroduction: Since ancient times, snakes have beenworshipped, feared, or loathed in South Asia. It is surprisingthat, snake bite poisoning is seldom mentioned as a priority forhealth research in a developing country like India. Keeping inview the above facts present study is conducted amongpatients of snake bites in and around Rewa, public awarenessof first-aid measures and clinical profile of the snake bitepatients.Material and Methods: The present study was carried outamong 160 patients of snake bites poisonous andnonpoisonous, admitted in Serious Patient Ward in Departmentof Medicine over a period of 26 months. All the patients ofpoisonous bites were observed for complications and managedaccordingly. Outcome was noted in the form of whether patientsurvived or died due to snake bite.Results: Ghabrahat (96.77%) and local pain (51.61%) werethe chief presenting complaints and tenderness (32.25%),redness (17.74%) at the local site were the main local findings,in non-poisonous group. In the poisonous group difficulty inopening of eyes (83.33%), difficulty in swallowing (77.78%),and difficulty in speaking (66.67%) were the main presentingcomplaints. Signs of envenomation in decreasing order werebilateral ptosis. (91.6%), bulbar palsy (72.85%), generalizedparesis (55.56%), drowsiness (44.44%) and varying degree ofrespiratory paralysis (25%) the main local effects in poisonousgroup tenderness (44.44 %), bleeding (22.2 %), redness(33.3%), oedema (27.7%). Of the total 36 cases, 30 (83.33%)survived and 6 (16.67%) died due to complications.Conclusion: It can be concluded from the study that generalpublic needs to be educated about pattern of behaviour ofsnakes, care while moving in night specially in fields, not tosleep on floors, importance of first aid specially use oftourniquet and immobilization of bitten parts not to waste timein seeking remedies from Ojhas etc and above all shift theaffected person at the earliest to nearest medical centre wherespecific therapy for dealing with such victims is available. Allthese measures will go a long way in saving many ofunfortunate victims of snake bite.Item Comparative Evaluation of Efficacy of PFN and PFN Antirotation in Treating Patients with Femur Fracture: An Hospital Based Study(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Didel, Rajendra; Choudhary, KusumBackground: Fractures of hip or proximal femur arefrequently observed and horrendous fractures that generallyafflict the elderly subjects with 90% observed in morethan 60 years age. Therefore; the present study wasconducted to evaluate the efficacy of PFN and PFN antirotation in managing patients with intertrochanteric femoralfractures.Materials and Methods: The present prospective survey wasperformed in the Department of Orthopaedics, GovernmentMedical College & Bangur Hospital, Pali, Rajasthan (India) andthe study enrolled 20 subjects with intertrochanteric fractures ofadults above than 21 years of age. Both the clinical andradiographic outcome of all the operated patients wasassessed. Functional outcome was assessed using the Harriship score. All the data thus obtained was arranged in atabulated form and analysed using SPSS software.Results: There were only 3 subjects less than 40 years of age,5 were between 40-60 years. The mean time to sit amongstGroup I patients was 2.8 days and Group II patients were 2.6days. The mean time to stand amongst Group I and Group IIsubjects was 5.1 days and 5 days. The preoperative meanscore in Group I and Group II was 50.1 and 51.4 respectively.Conclusion: From the above study it can be concluded thatboth the treatment modalities are equally efficacious inmanaging fractures of femurItem Frequency of Port Site Infection in Laparoscopic Cholecystectomies: An Hospital Based Study(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Kumar, Anil; Lal, MohanBackground: Port site infection (PSI), although infrequent, isone of the bothersome complications which undermine thebenefits of minimal invasive surgery. The aim of this study toevaluated the frequency of Port Site infections (PSI) inlaparoscopic cholecystectomies.Materials & Methods: This is a hospital based observationalstudy done on 20 cases with port site infection afterlaparoscopic cholecystectomy in the department of GeneralSurgery, Government Medical College, Pali. Wounds wereassessed clinically a week after surgery and in case infectionhad occurred; once weekly until 4 weeks in the out-patientsclinic. The frequency of port site infection studied in relationextent of infection, duration of surgery, intra-operative findings,site of port that was infected.Results: The mean age of patients was 43.26 years.According to the site of port infection, 19 patients (95%)developed an infection at the epigastric port and one patient(5%) developed an infection at the umbilical port, which was Pvalue was >0.05. The mean duration of surgery was 63.5minutes. The port site infection was present in 18 (90%)patients at 7 days and only 1 (5%) case had port site infectionat 30 days in our study.Conclusion: Laparoscopic cholecystectomy is associated witha low risk of port-site infection which in most the cases is onlysuperficial responding to local measures. Complication canoccur even in the best of hands and it is vital that these arerecognized properly and immediately addressed.Item Intraoperative Accidents Related to Transalveolar Removal of Wisdom Teeth(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Markam, H. S.; Chokotiya, Heeralal; Pradhan, SoniaBackground: Removal of wisdom teeth is a regularlyperformed dental treatment by non-specialist and specialistdentists. Damage to the inferior alveolar nerve after theremoval of wisdom molars occurred in 0.4 to 8.4% of subjects,lesser than 1% of cases it is permanent. The present studywas conducted with the aim to assess the intraoperativecomplications occurring during third molar removal.Materials and Methods: The residents of the departmentperformed all the dental surgical procedures. Classification ofthe impaction was done according to Pell and Gregory andWinter’s classification. The methods of osteotomy or toothsectioning, duration of surgery and any complications that wasencountered during the surgery like hemorrhage, displacementof teeth, damage to adjacent teeth or injury to soft tissues wasrecorded in a tabulated version.Student t test was used for analysis. Probability value of lessthan 0.05 was regarded as significant.Results: Fracture of tuberosity was seen in 2.3% cases, therewere 1% (n = 3) cases of hemorrhage, there were 0.6% (n = 2)cases each of apex fracture. There were two cases ofmesioangular impaction and 1 case of distoangular impaction.Conclusion: The most commonly associated intraoperativeaccident in the present study was tuberosity fractureItem Relevance of Routine Blood Pressure Associated Among Dental Patients in Patna, Bihar(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Priyanka; Kumar, Samir; Thakur, Manoj KumarBackground: Hypertension goes undetected due to absenceof sign and symptoms. Hence, it is often called the ‘silent killer’.The purpose of the present study was to determine therelevance of routine blood pressure associated among dentalpatients in Patna, Bihar.Materials and Methods: This study was conducted among 40patients of age 35-50 years over an period of 12 months.Relevant clinical history was taken. Trained dental personnel,using a standard mercury sphygmomanometer measured theBP. Patients who were found to have elevated BP of ≥ 140/90mm Hg, had their BP re-checked to confirm the elevated BPafter resting for 2 to 5 minutes. Patients were categorized intoStage 1 hypertension: clinic BP is 140/90 to 160/100 mm Hg.Stage 2 hypertension: clinic BP is 160/100 to 180/110 mm Hg.Severe hypertension: clinic systolic BP is 180 mm Hg or higheror clinic diastolic BP is 110 mm Hg or higher. Statisticalanalysis was done by using SPSS, version 22 (SPSS, Inc.,Chicago, IL) and p<0.05 was considered statisticallysignificant.Results: This total male population in the study was 22 and 18were female participants. On the basis of stage of hypertensionall the participants are equally distributed. 12 were male and 7were female of age group 31-40 years old. 10 were males and11 were females of age group 41-50 years old. In prehypersensitive stage, hypersensitive stage I and hypersensitivestage II males were having more systolic and diastolic bloodpressure than females whereas in severe hypertensionfemales were having more systolic and diastolic blood pressurethan males. Males were having higher hypertension thanfemales in age group 31-40 years age group but in age group41-50 females were having higher hypertension.Conclusion: The prevalence of hypertension is increasing withage in both men and women Therefore, our study recommendsthat regular checkup of blood pressure must be initiated so thatremedial measure can be initiated as early as possible.Item Treatment of Fracture Distal Tibia by Distal Tibial Locking Plate Verses Interlocking Nail: A Prospective Comparative Study(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Sharma, Sudesh Chander; Sharma, Sonali; Sudan, ShashiIntroduction: Fractures of distal third of tibia pose greaterchallenge to the treating surgeon, in view of its relative lack ofvascularity, as it is devoid of muscular envelope and is coveredonly by skin and tendons. Its proximity to the ankle joint makesit further complex than any diaphyseal fracture. A variety oftreatment modalities are available including non operative,external fixation, IM nailing and plating. Whereas, closedreduction and casting is known for redisplacement withresultant malunion and joint stiffness because of prolongedimmobilisation, external fixators are of utility only for compoundfractures of mid third and are known for pin track infections.Material and Methods: A Comparative prospective study oftwo procedures, for displaced fractures of distal third tibia inadults was conducted in Govt. Medical College (GMC),Jammu. 30 patients (Group A) were treated by ClosedReduction and fixation with IMIL Nailing and another 30 (GroupB) were treated by closed reduction and fixation using DistalTibial Locking Plate with MIPPO Technique. The patients werefollowed for a minimum of one year wherein the clinicalparameters, radiological progress and final functional resultswere evaluated as per American Orthopaedic Foot and AnkleSociety Score (AOFAS).Results: There was no significant difference in fracture healingtime or ambulation time. Good to Excellent results of 60% werefound in Group A and 73.3% in Group B. There were 13.3% ofpoor results in Group A as compared to 6.7% of Group B.Overall complication rate was higher in Group A. IMIL Nailinghad to be abandoned in 2 cases (6.7%) and switched on toDTLCP, due to per operative finding of medullary canal beingnarrower than 8 mm in one and curved in another. IMIL GroupA, also had 2 cases (6.7%) bent nail, 2 cases (6.7%) brokennail and another 3 cases (10%) of bent/broken locking bolts.No such implant related complications were observed inGroup B.Conclusion: IMIL Nailing is a technically demandingprocedure, requiring a thorough pre- operative work up and askilled experienced surgeon with all sizes of nails, reamers andalternative options available before contemplating it. However,DTLCP by MIPPO technique is easier to learn, is equallybiological, based on sound AO principles of indirect reductionand stabilization by extra periosteal fixed angle construct. Theprocedure has fewer per operative and postoperativecomplications and gives comparable or better results than IMILNailing. The choice of the procedure should be guided by thesite and geometry of fracture and individual experience of thetreating surgeon.Item To Study the Correlation between Iron Deficiency Anemia and HbA1c Levels in Non Diabetics(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Bansal, A; Mahajan, DS; Uppal, NPurpose: Iron deficiency anemia is the most occurring formof anemia in India. Hemoglobin A1c (HbA1c) is used in diabeticpatients as an maker to reflect glucose levels of the last 3months. Like blood sugar levelsHbA1c levels are also affectedby presence of variant hemoglobin, hemolytic anemia,nutritional anemias, uremia, pregnancy and acute blood loss.However, reports on the effects of iron deficiency anemia onHbA1clevels are inconsistent. We conducted this study with anaim to analyze the effects of iron deficiency anemia onHbA1clevels among non-diabetics.Methods: 200 patients with Hb<10g/dl underwent peripheralblood film testing. All patients with microcytic hypochromicanemia underwent iron studies .Out of these, 100 non diabeticpatients diagnosed with iron deficiency anemia underwentHbA1c test and data was statically analysed.Results: We found that incidence of iron deficiency anemiawas 54%. Serum iron and ferritin concentrations are inverselyassociated with HbA1c concentration and that HbA1cconcentration tended to be higher in the presence of irondeficiency anemia.Conclusion: This study found a positive correlation betweeniron deficiency anemia and increased HbA1c levels. Hence,Iron deficiency anemia has to be kept in mind before using theHbA1c to diagnose diabetes.Item Impact of Professional Nutrition Education on Dietary Behavior and Body Mass Index Status of Senior Clinical Nutrition Students and Dieticians in Saudi Arabia(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Al-amri1, Rahaf Sultan; Al-sobhi1, Sara Abdullah; AL-towairqi1, Manar Hamed; Hammouda, Sahar A IbrahimBackground: Dieticians are uniquely qualified to providenutrition education that can promote healthy lifestyles, reducethe burden of diet related chronic diseases, and improve thequality of life among population.Objectives: To evaluate the effectiveness of professionalnutrition education on changing dietary habits and achievementof normal BMI.Methodology: A cross sectional study. Subjects weregraduates from clinical nutrition departments and otherdepartments of Saudi Universities (n=225). Using internetstructured questionnaire focusing on dietary habits before andafter college education, physical activity and weight changes totest the impact of education on food habits both on the subjectand his/her surrounding environment (family and friends).Results: Increase consumption of fruits, vegetables, darkgreen vegetables, whole grain cereals, dairy products, andwater and increase physical activities, in addition to decreaseconsumption of soda, artificial canned juices, energy drinks,solid fat, added sugar, saturated fat and salt were clear amonggraduates of clinical nutrition departments in comparison toother graduates.Conclusion: Professional nutrition education positively impactfood choices and healthy food habits. This impact is extendedto their families and friends.Item Clinical, Hormonal and Metabolic Profile of Different Phenotypes of Polycystic Ovarian Syndrome(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Mahala, Neeti; Sharma, SeemaBackground: Polycystic ovarian syndrome (PCOS) is one ofthe most frequently encountered hormonal disorder withmetabolic abnormalities in females that can present at puberty,during reproductive age or even after menopause. Therefore,the aim of this study was to evaluate the occurrence of differentphenotypes among PCOS women and to compare thehormonal assay and metabolic profile of different phenotypesof PCOS.Materials & Methods: The present study was an observationalstudy conducted on 160 women of the age group of 16-35years and diagnosed with PCOS, in the department ofobstetrics and Gynecology at Mahatma Gandhi MedicalCollege and Hospital, Jaipur from January 2017 to July 2018.Diagnosis of PCOS was done by using the ESHRE/ASRMcriteria and subjects were divided into 4 phenotypes by usingthe all probable combination of Rotterdam criteria. Hirsutismwas assessed by using Modified Ferriman Gallwey score.Score <8 - Normal, 8-15- Mild and >15 indicate moderate tosevere hirsutism.Results: 160 PCOS women were distributed in 4 phenotypesand the most prevalent phenotype was phenotype D, 40.63%followed by 32.50% phenotype A and 14.38% phenotype C.Mean age of overall women was 24.94±4.86. In this studyoverall prevalence of metabolic syndrome was 37.5%. Almost50% women of phenotype A had metabolic syndrome followedby 35% of phenotype B, 34.78% of phenotype C and leastprevalence was in phenotype D 30.77%.Conclusion: We concluded that the most prevalent phenotypeis nonhyperandrogenic phenotype 40.63% and least commonphenotype is classic nonpolycystic ovaries phenotype(12.50%).Item Effect of Antenatal Dexamethasone Administration on Foetal and Uteroplacental Doppler Waveforms in Women at Risk of Spontaneous Preterm Birth: A Prospective Study(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Ahmed, A. Yassin; Abosrea, Mahmoud; Edris, Yehia; Abdelaziz, LobnaIntroduction: The effects of antenatal dexamethasone onfoetal and uteroplacental circulation as measured by Dopplerwaveform has gained more attention recently. In the presentstudy, we aimed to assess the change in foetal anduteroplacental circulation following antenatal dexamethasoneadministration to high-risk pregnant women.Methods: We conducted a prospective cohort study on 50pregnant women with high risk of preterm birth within thegestational age from 24 to 34 weeks. Two doses ofdexamethasone was administrated and. Doppler velocitywaveforms were obtained from the umbilical artery, fetal middlecerebral artery (MCA), fetal descending aorta and maternaluterine arteries Data analysis was carried out using SPSSversion 22 for Microsoft Windows.Results: The mean age of the included women were 27.9 ±4.8years while the mean parity was 2.14 ±1.4. Eighty percent ofthe children were alive at delivery. In terms of Doppler Indices,the umbilical artery pulsatility index (PI) and resistive indexshowed a statistically significant reduction afterDexamethasone administration (p <0.001). Similarly, theuterine and MCA arteries PI and RI showed a statisticallysignificant reduction after Dexamethasone administration (p<0.001). In terms of Cerebro-umbilical ratio (CUR), the ratioshowed a statistically significant increase after Dexamethasoneadministration (p =0.015). The CUR increased significantlyafter dexamethasone administration to reach 2.1 ±0.33. Onlyone patient had abnormal velicometry before and afterdexamethasone.Conclusion: In conclusion, the present study shows thatantenatal dexamethasone administration significantly improvethe fetal and uteroplacental hemodynamics, assessed byDoppler, among women with risk of preterm laborItem An Analytic and Clinical Correlation Study of Breast Lump(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Garhwal, B. S.; Chahar, Kapil Dev; Garhwal, Jyoti; Garhwal, PoojaIntroduction: Breast lump is commonly the presentingcomplaint. A dynamic physiological alter in female breastmakes it prone to diverse diseases, lump being the commonone. Transformation in the breast continue throughout the lifeso no age group is bar from the breast disorders. These lumpshave two main causes: benign and malignant breast disease.Materials and Methods: The study comprise of 70 cases ofbreast lump was assume at government hospital Sikar.Methods for evaluation of breast lump were anamnesis andphysical examination, which was supplement with radiologicalinvestigations. Finally a tissue diagnosis was obtained withFine needle aspiration cytology.Results: More than 70% of patients with menopause betweenage group of 45 - 49 years, 50% of Ca breast patients attaintheir menopause more than 7 years, whereas only 2 patientswith benign lumps were menopausal and both of thempresented after 7 years of menopause. Positive family historywas noted in around 15% and around 11% of patients ofmalignancy and benign lumps respectively.Conclusion: Benign breast lumps are more frequent thanmalignant ones. Benign lump was more frequent in 21-30years age group whereas Carcinoma in 41-50 years agegroup. Breast cancer occurs at younger age as compared towomen in west with more than 70% of patients being below 50years of age.Item Post-Operative Pain and Convalescence in Comparison of Laparoscopic Ventral Hernia Repair Vs Open Ventral Hernia Repair(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Rekhi, Harnam Singh; Mittal, Sushil; Khosa, Armaan; Arora, Sahil; P, Sathya; Singh, GagandeepBackground: Ventral hernia is defined as a fascial defectlocated to the abdominal wall. The laparoscopic repair ofIncisional and ventral hernia is fast becoming the standard ofcare.Objectives: To compare and evaluate the post-operative painand convalescence between two groups.Methods: Study was conducted on 30 cases of ventral herniaadmitted in Rajindra Hospital, Patiala. They were divided intotwo comparison groups (15 cases each). Group A: Openventral hernia repair; Group B: Laparoscopic ventral herniarepair.Results and Conclusions: Laparoscopic repair should be thepreferred method of repair of ventral hernia as it is associatedwith a shorter hospital stay, decreased post-operative pain,better cosmetic results decreased complication rate likerecurrence, and seroma formation, decreased mesh infectionrate, early ambulation period, better patient satisfaction andearly return to activities.Item Correlation of Serum Lipids with HbA1c in Individuals with Type 2 Diabetes Mellitus(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Lal, Darbari; Sharma, Hemant; Rohan, Tewani; Ishani, MahiBackground: Defects in insulin action and hyperglycemiacould lead to changes in plasma lipoproteins in patients withdiabetes.These Patients with type 2 Diabetes often exhibit anatherogenic lipid profile, which greatly increases their risk ofcardiovascular deaths compared with people withoutdiabetes.This dyslipidemia may be a treatable risk factor forsubsequent cardiovascular disease.Methods: The study was done at Hindu Rao Hospital Delhi. Aretrospective analysis of 52 patients with Diabetes was done.Patients who were diagnosed as per WHO guidelines fordiabetes mellitus and on statin therapy for at least 3 monthswere chosen for analysis.Results: Results of this study show that the levels of LDL,HDL, TC and TG were significantly higher in type 2 diabetics.Conclusion: Good glycaemic control is required for preventingother associated co-morbid conditions. Therefore,early diagnosis of dyslipidemia can be used as a preventivemeasure for the development of cardiovascular disease (CVD)in type 2 diabetics.Item Assessment of Denture Stomatitis Cases among Complete Denture Wearers(Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) Gupta, Niketa; Gupta, AnshulBackground: Denture stomatitis (DS) is a common oraldisease in denture wearers and quite characteristic ofadvanced age. The present study was conducted to assess thecases of denture stomatitis among complete denture wearers.Materials & Methods: The present study was conducted on445 completely edentulous patients wearing completedentures. In all patients, careful examination was done toevaluate the degree of the DS-modified Newton’s index (NI): 0= no inflammation; 1 = pin-point hyperemia; 2 = diffuseerythema; and 3 = papillary hyperplasia) 4, 5 in the completedenture wearers.Results: Out of 445 patients, males were 245 and femaleswere 200. The difference was non- significant (P- 0.1). Out of445 cases, DS was seen in 210 (47.1%) cases. 52% ofmaxillary and 43 % of mandibular dentures showed 0 grading,25% maxillary and 20% mandibular dentures showed 1grading, 13% maxillary and 25% mandibular dentures showed2 grading and 10% maxillary and 12% mandibular dentureshad 3 grading. The difference was significant (P< 0.05).Conclusion: Denture wearing habits, denture hygiene habits,denture cleanness and oral hygiene instructions madesignificant influence on the degree of DS in CD wearers. Hencein complete denture wearers, education is must to ensureproper cleanliness of the denture to prevent DS.