Myanmar Medical Journal
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Item Preliminary study of two major transfusion associated viral infections (Human Immunodeficiency Virus and Hepatitis B virus) during routine donor screening(1989-01-01) Soe Lwin; Khin Mya Lwin; Myint Myint Lwin; Khin Pyone Kyi; Khin Yi OoA total of 5973 blood donor specimens were tested for both HBsAg and HIV antibody, simultaneously. 2.18 per cent was initially reactive to ELISA, 0.67 per cent was repeatedly ELISA positive, 0.2 per cent was indeterminate and 0.39 per cent was confirmed for HIV antibody by IMMUMOBLOT ASSAY. The prevalence of HBsAg among blood donors was found to be 10.56 per cent with 11.1 per cent for male dornors and 5.06 per cent for female donors.Item Experiences in H.I.V infection in New Yangon General Hospital(1989-01-01) Aung Chein; Khin Ye Myint; Win Win Myint; Khay Mar Yee; Tint San; Hnin YeeClinical features of 11 cases of HIV infection are reported. Allwere males in a predominate age group of 25 - 34 years. 90.9 per cent were IVDAS and 90.9 per cent presented with acute infections 72.7 per cent had malaria infection mortality was 36.4 per cent.Item Clinical presentation of H.I.V positive intravenous drug abusers(1989-01-01) Rai Mra; Pe Than MyintOf 45 persons who were tested for the presence of HIV antibodies at Wards 1 & 2 , Yangon General Hospital from April 1989 to November 1989, all 26 HIV positive cases were male intravenous drug abusers (ELISA and Western blot tests positive). Mean age was 29.4 years . Pulmonary tuberculosis was the commonest presentation with 6 cases followed by infective endocarditis in 4 cases and seroconversion illness in 4. Other clinical presentations included septicaemia (3), viral hepatitis (2), drug overdose (3), malaria (3) and pneumonitis (1). Overall mortality was high nearly 40 per cent even though none of the cases had features of AIDS as defined by CDS/WHO.Item Incidence of Human Immunodeficiency Virus infection in drug abusers(1989-01-01) Khin Pyone Kyi; Soe Lwin; Khin Mya Lwin; Myint Myint Lwin; Khin Yi OoA total of 1035 drug abusers were screened for HIV-antibodies. 19 per cent are positive for anti-HIV in drug addict using drugs by various routes including intravenous routes. Where as 51.3 per cent of intravenous drug abusers were positive. Even among IVDA, hospitalized cases are 70 per cent positive against 40.9 per cent in non-hospitalized cases.Item Current views on HIV infection and Aids(1989-01-01) Rai Mra; Pe Than MyintItem First case of AIDS diagnosed in Myanmar(1989-01-01) Nyunt WinItem Laboratory aspects of Human Immunodeficiency Virus infection and Acquired Immunodeficiency Syndrome(1989-01-01) Soe Lwin; Khin Pyone Kyi; Khin Yi OoItem Myanmar essential drugs programme(1989-06-01) Khin Kyi KyiItem Recent trends in management of Bronchial Asthma(1989-06-01) Kyaw MyintItem Essential drug and primary health care (Editorial)(1989-06-01)Item A clinical evaluation of Chloroquine and Quinine therapy in falciparum malaria infection(1989-06-01) Myint Myint Aye; Kyaw San HlaItem Disposition kinetics of infusion quinine in (Adult) Myanmar falciparum malaria patients(1989-06-01) Cho Cho Myint; Tin Shwe; Pe Than MyintTo study the pharmacokinetics of infusion quinine in Myanmar patients, 14 adults with falciparum malaria (half of them were highly parasitised i.e more than 5Item Essential drugs(1989-06-01) Hla MyintItem Comparative trial of different dose schdules of monospecific antivenom for Russell's viper(1989-06-01) Myint Lwin; Tin Nu Swe; Myint Aye Mu; Than Than; Tun PeAn open comparative trial of two different dose schedules of Myanma Pharmaceutical Industry (MPI) monospecific Russell's viper venom (ASV) was carried out in 45 confirmed cases of Russell's viper envenoming. Patients included in the study were randomised by drawing lots and divided into two groups. Group one received an initial bolus dose of 40 ml of ASV (intravenous over 10 minutes) and if blood remains incoaguable 6 hours after the initial dose another dose of 40 ml was given. Group two received a bolus dose of 80 ml (intravenous over 20 minutes). Response to treatment was assessed clinically and serial measurements of blood venom antigen, coagulation factors and biochemical variables. 40 ml was found to be adequate in 48Item Russell's viper bite : pathophysiology, clinical features in current trend in management(1989-06-01) Myint Lwin; Tin Nu Swe; Myint Aye MuItem Endotoxin in jejunal fluid of patients with acute watery diarrhoea due to vibrio cholera EL tor infection(1989-06-01) Khin Maung U; Pyone AyeJejunal fluids were collected from ten adults with cholera (stool culture for Vibrio cholera El for positive) and ten adults with non-cholera watery diarrhoea admitted to Infectious Diseases Hospital. By limulus amoebocyte lysate gelation test using chloroform extraction, "endotoxin" (lipopolysaccharide) was detected in half of patients with cholera and none of patients with noncholera diarrhoea. Patients in whose jejunal fluids endotoxin was detected were older, had smaller body weights, purged less diarrhoeal stools, fewer motions and for a shorter duration, vomitted 1.36 litres on the average, and required less intravenous and oral rehydration fluids than cholera patients without detectable "endotoxin" in their jejunal fluids. These findings suggest that presence of "endotoxin" of V. cholera El Tor in the gut lumen did not cause more severe diarrhoea.Item The evaluation of whole blood prothrombin time in Russell's Viper Bite cases(1989-06-01) Than Than; Khin Ei HanThe Evaluation of whole blood prothrombin time was done in 3 groups of Russell's viper bite victims: 20 with incoagulable blood on admission, 19 with coagulable blood only on admission and 16 with coagulable blood throughout. The laboratory results suggest that the whole blood prothrombin time is as useful as 20 minutes whole blood clotting time test in indicating for starting antivenom therapy in patients with incoagulable blood on admission but not for the need to repeat the therapy. It is also not as useful as serial monitoring of fibrin (ogen) degradation products in discriminating patients with (or) without progressive defibrination.Item Adenomyomatous polyp of left hepatic duct(1990-01-01) Kyi Soe; Thi Thi Aye; Myint Soe; Khin Maung Kyi; Thein NyuntA case report of adenomyomatous polyp originating from the left hepatic duct causing surgical jaundice is made. Adenomyomatous polyp originating from the left hepatic duct is histologically similar to adenomyomatous hyperplasiaof the gall bladder as shown in the references above. In various journals available here, this type of polyp with its origin from hepatic duct has not been mentioned. Another important point is that it can be mistaken radiologically & clinically as cholangio carcinoma causing obstructive jaundice.Item Lamprene (clofazimine) on patients with vertiligo(1990-01-01) Tin Shwe; Pangi, CharlesItem A Comparative study of Amodiaquine and Chloquine in the treatment of Falciparum Malaria(1990-01-01) Thet Naing; Hla Win; Yin Yin Nwe; Tin Shwe75 patients were studied in Tauggyi, Shan State where chloroquine resistant falciparum malaria is prevalent. Response of the patients were followedup to 7 days for assessment, one group to chloroquine & another group to amodiaquine. In sensitive patients there was no difference in terms of fever and parasite clearence but in terms of treatment failures cholroquine was 48.8percent and amodiaquine was 20 percent.