Browsing by Author "Lal, Niharika Ranjan"
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Item A Boy with Claw Fingers.(2012-03) Mondal, Ashim Kumar; Lal, Niharika Ranjan; Kumar, PiyushItem Ichthyosis follicularis, atrichia and photophobia (IFAP) syndrome affecting two successive generations in an Indian family.(2016-09) Lal, Niharika Ranjan; Bandyopadhyay, Debabrata; Misra, Saheli; Sarkar, Asim Kumar; Rao, SudhakarItem Lupus vulgaris in a child: A complication of ear piercing.(2014-01) Kumar, Piyush; Mondal, Avijit; Lal, Niharika Ranjan; Gharami, Ramesh ChandraItem Palmar pits and epidermodysplasia verruciformis: A rare association.(2012-07) Kumar, Piyush; Lal, Niharika Ranjan; Gharami, Ramesh ChandraItem Safety and effectiveness of autoinoculation therapy in cutaneous warts: A double - blind, randomized, placebo - controlled study.(2014-11) Lal, Niharika Ranjan; Sil, Amrita; Gayen, Tirthankar; Bandyopadhyay, Debabrata; Das, Nilay KantiBackground: In spite of the availability of multiple treatment options, viral warts are known for their persistence and recurrence, causing frustration to patients and treating physicians. Aims: To study the effectiveness and safety of autoinoculation as a treatment modality in cutaneous warts. Methods: A double‑blind, placebo‑controlled study was carried out. In the treatment group, full‑thickness warty tissue was excised, minced and implanted in a small dermal pocket. In the control group, warty tissue was only excised and not implanted, though a dermal pocket was made. Patients were evaluated every four weeks with lesion counts. The procedure was repeated at 4 and 8 weeks. Response was assessed at each visit and at 12 weeks. Results: Forty‑eight patients with cutaneous warts (male: female = 32:16) were randomized into autoinoculation and control groups. The number of warts at baseline was comparable in both groups (P = 0.293). Reduction in the number of warts was significantly more in the autoinoculation group (8.50 ± 13.88) than in the control group (10.04 ± 5.80) from 8 weeks onwards (P = 0.010). Complete resolution occurred only in the autoinoculation group, in 62.5% of cases. Adverse effects were seen in 11 patients, including infection of the donor site (5 cases), keloid formation (3) and hypopigmentation (3). Conclusion: Autoinoculation may be an effective therapeutic modality for cutaneous warts and two sessions may be required for optimum results.Item Safety of important dermatological drugs (retinoids, immune suppressants, anti androgens and thalidomide) in reproductively active males with respect to pregnancy outcome: A brief review of literature(Indian Association of Dermatologists, Venereologists & Leprologists, 2018-09) Kumar, Piyush; Das, Anupam; Lal, Niharika Ranjan; Jain, Sourabh; Ghosh, AnupamaPaternally transmitted damage to offspring is recognized as a complex issue. Each parent contributes 23 chromosomes to a child; hence, it is necessary to know the effects of both maternal and paternal pre-and peri-conceptional exposure to drugs on pregnancy outcome. While there are many studies on the effects of maternal drug exposure on pregnancy outcome, literature on paternal exposure is scarce. Of late however, paternal exposure has been receiving increasing attention. We present a brief review on the safety of commonly used drugs in dermatology, focused on retinoids, immune suppressants, anti androgens and thalidomide.