Safety of important dermatological drugs (retinoids, immune suppressants, anti androgens and thalidomide) in reproductively active males with respect to pregnancy outcome: A brief review of literature

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Date
2018-09
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Journal ISSN
Volume Title
Publisher
Indian Association of Dermatologists, Venereologists & Leprologists
Abstract
Paternally transmitted damage to offspring is recognized as a complex issue. Each parent contributes 23 chromosomes to a child; hence, it is necessary to know the effects of both maternal and paternal pre-and peri-conceptional exposure to drugs on pregnancy outcome. While there are many studies on the effects of maternal drug exposure on pregnancy outcome, literature on paternal exposure is scarce. Of late however, paternal exposure has been receiving increasing attention. We present a brief review on the safety of commonly used drugs in dermatology, focused on retinoids, immune suppressants, anti androgens and thalidomide.
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Keywords
Antiandrogen, immunosuppressive, reproductively active male, retinoid, safety of drugs, thalidomide
Citation
Kumar Piyush, Das Anupam, Lal Niharika Ranjan, Jain Sourabh, Ghosh Anupama. Safety of important dermatological drugs (retinoids, immune suppressants, anti androgens and thalidomide) in reproductively active males with respect to pregnancy outcome: A brief review of literature. Indian Journal of Dermatology, Venereology and Leprology. 2018 Sep; 84(5): 539-546