Journal of Clinical and Biomedical Sciences

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Adenosquamous Cell Carcinoma Secondary to Chronic Osteomyelitis of the Tibia - Rare Case Report
(Sri Devaraj Urs Academy of Higher Education, 2024-04) Anil, KP; Nagakumar, JS.
Osteomyelitis is an infection with progressive destruction of bone tissue involving the bone and articular cartilage with its medullary canal. Chronic osteo-myelitis treatment is challenge for the orthopaedician. The bone microscopic anatomy and also the microorganism biofilms and their ability to adapt to their surrounding environment. It’s tough for the antibiotics and disinfectants to breach the biofilm barrier and kill these microorganism colonies. Cutaneous neoplasm are a rare complication developing after a chronic bone infection. The incidence and prevalence of these cutaneous tumor/neoplasm following chronic bone infection continues to increase despite the increasing awareness to the disease process, and medical advances in early diagnosis and early treatment. Most common neoplasm after a chronic bone infection are squamous cell carcinoma and rarely sarcoma or lymphoma. 1 In our study we report adenosquamous cell carcinoma arising from chronic osteomyelitis of tibia for which above knee amputation was done.