Antibiotic utilization profile in surgical ward at secondary government hospital

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dc.contributor.authorMarchiella, R.en_US
dc.contributor.authorKhairunnisa, K.en_US
dc.contributor.authorWiryanto, W.en_US
dc.date.accessioned2024-09-24T06:14:01Z
dc.date.available2024-09-24T06:14:01Z
dc.date.issued2024-02
dc.description.abstractBackground: This study aimed to determine the profile of the antibiotic utilization in defined daily dose (DDD) units and DU 90% at surgical ward of secondary government hospital in Indonesia within six months period of study. Methods: A retrospective cross-sectional study was conducted over six months on surgical ward patients prescribed with at least one oral or parenteral antibiotic during hospitalization. Data were collected from pharmacy dispensing data and evaluated using World Health Organization (WHO) DDD. Antibiotics DDD were analysed using DU 90% segmentation in order to know the 90 percent cumulative of antibiotic consumption in surgical ward. WHO prescribing indicators were used to examine the antibiotic prescribing pattern in DU 90% segment. Results: Out of 319 antibiotic prescribed to surgical ward patients, 219 prescriptions were belonging to DU 90% segment including ceftriaxone (38.94%), moxifloxacin (16.41%), fosfomycin (14.06%), metronidazole (12.43%), and gentamicin (7.69%) in decreasing fashioned. Of the five groups of antibiotics belong to DU90%, ceftriaxone was the highest in DDD (272.5). The average number of antibiotic prescribed to patients were 1.64±0.92. The percentage of antibiotic prescribed by its generic name as well the prescribing of antibiotic from National list of essential medicines were 70.79% and 72.51%, respectively (optimal value 100%). Conclusions: Our findings on using drug utilization 90% and prescribing indicators are practical for assessing the most widely used antibiotics in ward or hospital setting and to evaluate the quality of prescribing pattern. The antibiotic utilization profile in this study can be used to provide comparative data between hospital and beneficial for future policy making to improve prescribing practice.en_US
dc.identifier.affiliationsDepartment of Pharmaceuticals Sciences, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesiaen_US
dc.identifier.affiliationsDepartment of Pharmacology and Clinical/Community Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesiaen_US
dc.identifier.affiliationsDepartment of Pharmacology and Clinical/Community Pharmacy, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesiaen_US
dc.identifier.citationMarchiella R., Khairunnisa K., Wiryanto W.. Antibiotic utilization profile in surgical ward at secondary government hospital. International Journal of Basic & Clinical Pharmacology. 2024 Jan; 13(1): 51-56en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/226769
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber1en_US
dc.relation.volume13en_US
dc.source.urihttps://doi.org/10.18203/2319-2003.ijbcp20233891en_US
dc.subjectDU 90%en_US
dc.subjectATC/DDDen_US
dc.subjectPrescribing indicatorsen_US
dc.subjectDrug utilizationen_US
dc.subjectDURen_US
dc.titleAntibiotic utilization profile in surgical ward at secondary government hospitalen_US
dc.typeJournal Articleen_US
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