Effect of Aging On Short Term Heart Rate Variability.
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Date
2014-12
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Abstract
Background: Heart rate variability has been considered as an indicator of autonomic nerve function
status. Few works have been done to assess the heart rate variability in normal healthy subjects in
different countries. Objectives: To assess the cardiac autonomic nerve function status in healthy
Bangladeshi population of different age groups by analyzing time domain measures of Heart Rate
Variability. Methods: This cross sectional study was conducted in the Department of Physiology,
Dhaka Medical College, Dhaka from the period of July 2012 to June 2013. For this purpose, a total
number of 180 healthy subjects were selected with the age ranging from 15-60 years of both sexes. All
the study subjects were divided into 3 different groups according to age (Control 15-30 years; middle
age 31-45 years; older age 46-60 years). Each group included 60 subjects of which 30 were male and 30
were female. The subjects were selected from different areas of Dhaka city by personal contacts. HRV
parameters were recorded by a 4 active channels, RMS Polyrite-D-2 machine For statistical analysis,
one way ANOVA, unpaired Student’s ‘t’-test and Pearson’s correlation coefficient test were performed.
as applicable. Results: Systolic blood pressure (SBP), diastolic blood pressure (DBP) were significantly
(p<0.001) higher in older group in comparison to control & middle age group. Again RR interval and
RMSSD (p<0.001), were significantly lower in older age group (p<0.05) compared to control & also to
middle age group. But HR was found significantly higher (p<0.05)in both middle and older subjects
than control and also in older (p<0.05) compared to middle age. Correlation analysis showed moderate
negative correlation of mean R-R with age in middle age whereas significant negative correlation for
RMSSD both in middle and older age subjects.. Conclusion: In this study, markedly decreased cardiac
parasympathetic function were found with aging process.
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Keywords
R-R, HR, RMSSD, older age, middle age
Citation
Akhter Qazi Farzana, Akhter Qazi Shamima, Rohman Farhana, Sinha Susmita, Ferdousi Sybilla. Effect of Aging On Short Term Heart Rate Variability. Journal of Bangladesh Society of Physiologists. 2014 Dec; 9(2): 78-82.