Adrenocorticotropic hormone production in breast cancer.
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Date
2005-01-05
Authors
Poddar, Nitesh Kumar
Saha, Renuka
Hedau, Suresh
Ray, Amitabha
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Abstract
Presence of adrenocorticotropic hormone (ACTH) was investigated in tissues from 150 cases of primary breast cancer. ACTH peptides were detected in 16.7% cases and ACTH expression was higher in post-menopausal cancers. A significant association was noticed between the presence of ACTH and the positive estrogen receptor (ER) status of tumors. The study indicated a probable role of these ectopic ACTH peptides in steroid hormone related pathology of breast cancer.
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Poddar NK, Saha R, Hedau S, Ray A. Adrenocorticotropic hormone production in breast cancer. Indian Journal of Experimental Biology. 2005 Jan; 43(1): 35-9