Effect of storage duration on cell cycle kinetics and yield of chromosomal aberrations in PHA-responsive human peripheral blood lymphocytes.

Simple item page
dc.contributor.authorJha, A Nen_US
dc.contributor.authorSharma, Ten_US
dc.date.accessioned2009-05-28T11:40:55Z
dc.date.available2009-05-28T11:40:55Z
dc.date.issued1992-08-01en_US
dc.description.abstractPhytohaemagglutinin (PHA)-responsive lymphocytes from human peripheral blood samples, either irradiated or un-irradiated, showed increased frequency of first division metaphase cells (detected by fluorescence plus Giemsa (FPG) staining) as a function of duration of storage. Irradiated and subsequently stored samples showed small but significant increase for the yield of dicentrics. The yield of aberrant metaphases and deletions (excess acentrics) remained unchanged. Increasing Bromodeoxyuridine (BrdU) concentrations slowed down the cell cycle progression but did not influence the yield of aberrations including that of dicentrics.en_US
dc.description.affiliationCytogenetics Laboratory, Banaras Hindu University, Varanasi, India.en_US
dc.identifier.citationJha AN, Sharma T. Effect of storage duration on cell cycle kinetics and yield of chromosomal aberrations in PHA-responsive human peripheral blood lymphocytes. Indian Journal of Experimental Biology. 1992 Aug; 30(8): 664-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/57053
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnalysis of Varianceen_US
dc.subject.meshBlood Preservation --adverse effectsen_US
dc.subject.meshBromodeoxyuridine --pharmacologyen_US
dc.subject.meshCell Cycle --drug effectsen_US
dc.subject.meshChromosome Aberrationsen_US
dc.subject.meshChromosomes --drug effectsen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphocytes --cytologyen_US
dc.subject.meshPhytohemagglutininsen_US
dc.subject.meshTime Factorsen_US
dc.titleEffect of storage duration on cell cycle kinetics and yield of chromosomal aberrations in PHA-responsive human peripheral blood lymphocytes.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Experimental Biology