Assessment of Percentage Saturation of Hemoglobin with Oxygen in Arterial Blood of Pregnant Women.
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Date
2006-12
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Abstract
Objective: Percentage saturation of hemoglobin with oxygen in arterial blood (SaO2) was studied in
pregnant women to evaluate the lung function status in pregnancy. Methods: This study was conducted
in the department of physiology in Dhaka medical college during July 2004 to June 2005. For this
purpose total 32 women with age ranged 25-35 years without any recent history of respiratory diseases
were selected from Dhaka city. Eight (8) age matched apparently healthy women was taken as control
and Twenty four (24) normal pregnant women without any complication were included in experimental
group. All pregnant subjects were studied during first, second and third trimester. SaO2 was determined
by “Easy Blood Gas Auto Analyzer”. SaO2 during different trimesters were compared with that of
non pregnant and also among the trimesters. Statistical analysis was done by students unpaired ‘t’ test.
Result: Mean ±SD SaO2 during first trimester (97.73%±0.92), second trimester (98.05%±0.54) and
third trimester (98.40%±0.30) were progressively increasing and were significantly higher (p<0.05,
p<0.001, p<0.001) than that of non pregnant women (96.71±0.63). But no statistically significant
differences were observed among the trimesteric values. The present result indicates increased lung
function in pregnant women associated with progressively increased oxygen saturation with trimester.
Higher progesterone level is related to increased ventilation which is more marked in luteal phase of
menstrual cycle. In pregnant women gradually rising progesterone level reaches its peak at the later
part of pregnancy.
Conclusion: Therefore it may be concluded from the present study that progressively increased SaO2
might be related to hyperventilation induced by high progesterone level.
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Keywords
Pregnant women, trimester, progesterone
Citation
Sunyal D K, Amin M R, Molla M H, Ahmed A, Ferdousi S, Khatun F. Assessment of Percentage Saturation of Hemoglobin with Oxygen in Arterial Blood of Pregnant Women. Journal of Bangladesh Society of Physiologists. 2006 Dec; 1(1): 10-13.