Impact of Cancer on Survival of Patients with AKI on CRRT.

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dc.contributor.authorKim, Ye Na
dc.contributor.authorShin, Ho Sik
dc.date.accessioned2016-03-16T04:58:11Z
dc.date.available2016-03-16T04:58:11Z
dc.date.issued2015
dc.description.abstractBackground: Few studies have examined cancer patients with acute kidney injury (AKI) who require continuous renal replacement therapy (CRRT). The aim of this study was to compare the characteristics and outcomes of patients with and without cancer requiring CRRT for AKI in general intensive care units (ICUs). Methods: We studied a retrospective cohort study in an ICU. A total of 200 patients (without cancer 79%; with cancer 21%) were included over a 24 month period. Predictors of all-cause death were examined using Kaplan-Meier and Cox proportional hazards analyses in both treatment groups for statistical analysis. Results: The 1st contributing factors of AKI was cardiac dysfunction (40%) and 2nd factors was sepsis (38%). The cause of AKI was multifactorial in 78% of cancer patients and in 71% of patients without cancer. Hospital mortality rates were higher in patients with cancer (69%) than in patients without cancer (49.4 %) (P = 0.023). In multivariate analyses, older age, medical admission, poor chronic health status, comorbidities, ICU days until RRT start, number of associated organ dysfunctions, and diagnosis of cancer were associated with hospital mortality. The diagnosis of cancer was independently associated with mortality [odds ratio = 1.68 (95% confidence interval, 1.10–2.59), P = 0.017]. Conclusions: The presence of cancer may be independently associated with mortality in our study.en_US
dc.identifier.citationKim Ye Na, Shin Ho Sik. Impact of Cancer on Survival of Patients with AKI on CRRT. British Journal of Medicine and Medical Research. 2015; 5(6): 758-766.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/175944
dc.language.isoenen_US
dc.source.urihttps://sciencedomain.org/abstract/6412en_US
dc.subjectAcute kidney injuryen_US
dc.subjectcanceren_US
dc.subjectcontinuous renal replacement therapyen_US
dc.titleImpact of Cancer on Survival of Patients with AKI on CRRT.en_US
dc.typeArticleen_US
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