Expanded Indian National Rotavirus Surveillance Network in the Context of Rotavirus Vaccine Introduction.
| dc.contributor.author | Mehendale, Sanjay | |
| dc.contributor.author | Venkatasubramanian, S | |
| dc.contributor.author | Kumar, CP Girish | |
| dc.contributor.author | Kang, Gagandeep | |
| dc.contributor.author | Gupte, MD | |
| dc.contributor.author | Arora, Rashmi | |
| dc.date.accessioned | 2016-12-01T04:29:19Z | |
| dc.date.available | 2016-12-01T04:29:19Z | |
| dc.date.issued | 2016-07 | |
| dc.description.abstract | Objective: To extend a nation-wide rotavirus surveillance network in India, and to generate geographically representative data on rotaviral disease burden and prevalent strains. Design: Hospital-based surveillance. Setting: A comprehensive multicenter, multi-state hospital based surveillance network was established in a phased manner involving 28 hospital sites across 17 states and two union territories in India. Patients: Cases of acute diarrhea among children below 5 years of age admitted in the participating hospitals. Results: During the 28-month study period between September 2012 and December 2014, 11898 children were enrolled and stool samples from 10207 children admitted with acute diarrhea were tested; 39.6% were positive for rotavirus. Highest positivity was seen in Tanda (60.4%) and Bhubaneswar (60.4%) followed by Midnapore (59.5%). Rotavirus infection was seen more among children aged below 2 years with highest (46.7%) positivity in the age group of 12-23 months. Cooler months of September – February accounted for most of the rotavirus-associated gastroenteritis, with highest prevalence seen during December – February (56.4%). 64% of rotavirus-infected children had severe to very severe disease. G1 P[8] was the predominant rotavirus strain (62.7%) during the surveillance period. Conclusions: The surveillance data highlights the high rotaviral disease burden in India. The network will continue to be a platform for monitoring the impact of the vaccine. | en_US |
| dc.identifier.citation | Sanjay Mehendale, S Venkatasubramanian, CP Girish Kumar, Gagandeep Kang, MD Gupte and Rashmi Arora. Expanded Indian National Rotavirus Surveillance Network in the Context of Rotavirus Vaccine Introduction. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/179114 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.indianpediatrics.net/july2016/july-575-581.htm | en_US |
| dc.subject | Epidemiology | en_US |
| dc.subject | Rotavirus diarrhea | en_US |
| dc.subject | Vaccine | en_US |
| dc.title | Expanded Indian National Rotavirus Surveillance Network in the Context of Rotavirus Vaccine Introduction. | en_US |
| dc.type | Article | en_US |