Diagnosis of Hyperparathiroidism after Surgical Treatment of OsteolyticLesion

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dc.contributor.authorAgnone, Aen_US
dc.contributor.authorCiccarelli, Een_US
dc.contributor.authorGiordano, Luen_US
dc.contributor.authorAbbona, Gen_US
dc.contributor.authorSaracco, Ren_US
dc.date.accessioned2019-12-06T09:21:09Z
dc.date.available2019-12-06T09:21:09Z
dc.date.issued2018-09
dc.description.abstractSeveral metabolic diseases can affect normal process of osteogenesis, involving the formation of a collagen matrix, where the salts that form the bone are deposited. The homeostasis of calcium and phosphate metabolism is regulated by the activity of the parathyroid glands, whose alterations are associated with bone modifications. Parathyroid hormone (PTH) exerts profound effects on skeletal homeostasis through several cellular and molecular mechanisms. Chronic hyperparathyroidism causes net loss of bone mass, despite accelerating bone formation by osteoblasts. An increased secretion of PTH, caused for example by an adenoma of the parathyroid glands, can induce the formation of a central giant cellular lesion of the jaws known as Brown’s Tumour of the jaws, that may lead to evident osteolysis and gross deformity in the maxillofacial region. This may be the first presentation of this disease. The authors report a 79-years-old male patient who presented with an asymptomatic osteolytic lesion in the right maxilla as the first manifestation of primary hyperparathyroidism, caused by a parathyroid adenoma. The authors describe the surgical treatment of the maxillary lesion, the procedure that led to the diagnosis of hyperparathyroidism and its treatment.en_US
dc.identifier.affiliationsDepartment of Dentistry and Maxillo-Facial Surgery SC Chief M. Giordano Martini Hospital, Turin, Italy.en_US
dc.identifier.affiliationsDepartment of Endocrinology, SS Dr Ciccarelli Martini Hospital, Turin, Italy.en_US
dc.identifier.affiliationsDepartment of Phatology SC Chief Dr Taraglio, Martini Hospital, Turin, Italy.en_US
dc.identifier.affiliationsDepartment of General Surgery, SC Chief Dr Saracco R, Martini Hospital, Turin, Italy.en_US
dc.identifier.citationAgnone A, Ciccarelli E, Giordano Lu, Abbona G, Saracco R. Non-Surgical Periodontal Therapy- A Noteworthy Contribution towards Oral Health. Annals of International medical and Dental Research. 2018 Sep; 4(5): 8-11en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/188295
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber5en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.21276/aimdr.2018.4.5.DE2en_US
dc.titleDiagnosis of Hyperparathiroidism after Surgical Treatment of OsteolyticLesionen_US
dc.typeJournal Articleen_US
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