Serum high sensitive c-reactive protein and anticardiolipin antibody level in cad patients with and without type 2 diabetes mellitus.
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Date
2012-07
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Abstract
The increased incidence of coronary artery disease (CAD) in Type 2 Diabetes mellitus is not fully
explained by the conventional risk factors. Our aim was to determine the association of biomarkers, high
sensitive CRP and anticardiolipin antibody (acL) with severity of coronary artery disease in patients with and
without type 2 DM. In our study, hsCRP level was significantly high in CAD with DM and found to be
positively correlated with severity (p<0.01) while anticardiolipin antibody does not show any significant change
among the two groups. Our study concluded that increased risk of CAD in type 2 DM patients is not only
because of dyslipidemia but inflammatory events also play a major role. hsCRP was found to be a valuable
predictor for CAD in type 2 DM.
Description
Keywords
Coronary artery disease, Atherosclerosis, anticardiolipin antibody, high sensitive C-reactive protein
Citation
Philip Sachu, Abraham Philips, Kanakasabai G, Sethupathy S, Sheriff D S. Serum high sensitive c-reactive protein and anticardiolipin antibody level in cad patients with and without type 2 diabetes mellitus. International Journal of Applied Biology and Pharmaceutical Technology. 2012 Jul-Sept; 3(3): 196-202.