Utility Of Cartridge Based Nucleic Acid Amplification Test (cbnaat) In The Diagnosis Of Tubercular Pleural Effusion

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dc.contributor.authorBairwa, Mahesh Chanden_US
dc.contributor.authorFatehpuria, Chandan Malen_US
dc.contributor.authorBanera, Mahendra Kumaren_US
dc.date.accessioned2019-11-25T05:22:13Z
dc.date.available2019-11-25T05:22:13Z
dc.date.issued2019-09
dc.description.abstractIntroduction: TB is one of the top 10 causes of death globally. PTB is most common presentation. Lymph node TB is the most common type of EPTB constitutes about 35% cases followed by pleural effusion(20%), bone and joint(10%), genitourinary TB(9%), TB Meningitis(5%), abdominal tuberculosis(3%), other(10%). WHO also recommends Gene Xpert MTB/RIF over conventional tests which permits rapid TB diagnosis through detection of the genetic sequence of DNAof mycobacterium TB and simultaneous identification of a majority of the mutations that confirm Rifampicin resistance which is highly predictive of MDR-TB. Methodology: Study was carried out over a period of one year in a tertiary care centre. Patients with suggestive of pleural effusion were included in study. Pleural fluid was drawn using standard protocol and sent for CBNAAT test and bacteriological examination. Based on MTB result, the study population were divided into 'MTB detected' and 'MTB not detected' groups. MTB detected group was further divided into 'Rif' Resistant and 'Rif' sensitive group. All the collected information was filled in predesigned proforma in excel sheet for final analysis. Chi squire test or suitable formula was applied to know the significance of our study. Results: 203 patients were included with a male to female ratio of 2.98:1. 65.91% patients were below 45 years of age. Mostly patients were from rural areas and illiterate. 38.64% had different type of substance abuse habit. DM (29.03%) found as the most common co-morbidities. CBNAAT test was able to detect MTB in 76 (37.44%) extra-pulmonary samples, 70 were Rifampicin sensitive and 6 were 'Rifampicin' resistant.en_US
dc.identifier.affiliationsSenior Resident, Department of Respiratory medicine, RNT Medical College, Udaipur, Rajasthan, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Community medicine, RNT Medical College, Udaipur, Rajasthan, Indiaen_US
dc.identifier.affiliationsSr. Professor, Department of Respiratory medicine, RNT Medical College, Udaipur, Rajasthan, Indiaen_US
dc.identifier.citationBairwa Mahesh Chand, Fatehpuria Chandan Mal, Banera Mahendra Kumar. Utility Of Cartridge Based Nucleic Acid Amplification Test (cbnaat) In The Diagnosis Of Tubercular Pleural Effusion. Indian Journal of Applied Research. 2019 Sep; 9(9): 17-20en_US
dc.identifier.issn2249-555X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/185158
dc.languageenen_US
dc.publisherWorld Wide Journalsen_US
dc.relation.issuenumber9en_US
dc.relation.volume9en_US
dc.subjectMTBen_US
dc.subjectRIFen_US
dc.subjectCBNAATen_US
dc.subjectMDRen_US
dc.titleUtility Of Cartridge Based Nucleic Acid Amplification Test (cbnaat) In The Diagnosis Of Tubercular Pleural Effusionen_US
dc.typeJournal Articleen_US
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