The use of medicinal plants for the treatment of psoriasis: A systematic review and meta-analysis

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dc.contributor.authorGonçalves, Gisele MSen_US
dc.contributor.authorWenceslau, Laina Ren_US
dc.contributor.authorMendonça, Jose Alexandreen_US
dc.date.accessioned2023-08-10T07:30:55Z
dc.date.available2023-08-10T07:30:55Z
dc.date.issued2023-08
dc.description.abstractBackground: Psoriasis is a chronic inflammatory disease that presents as scaly patches on the skin that affects about 3% of the world's population. Adherence to treatment and discrimination against people are common problems, adversely impacts quality of life. Objectives: The aim of this study was to investigate the use of medicinal plants as therapeutic adjuvants in the treatment of plaque psoriasis through a systematic review and meta-analysis. Methods: A systematic review and meta-analysis of randomized controlled trials in patients with plaque psoriasis was carried out, comparing the efficacy of herbal treatments alone or in association with other therapies. The search was performed in the databases of The Cochrane Library, Lilacs, Medline via PubMed and Embase, only including studies published from 2016 to 2020.The certainty of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework. A systematic review and meta-analysis of randomized controlled trials (RCT) in patients with plaque psoriasis was carried out, comparing the efficacy of herbal treatments alone or in association with other therapies. We comprehensively searched the MEDLINE, Embase, Lilacs and Cochrane Library databases, only including studies published from 2016 to 2020. The certainty of evidence was assessed using the GRADE approach. Results: Out of 2,268 articles evaluated, only seven RCT were eligible for final analysis. Five of these studies evidenced low risk of bias and a high level of evidence. Limitations: Few RCT of medicinal plants. Conclusion: This meta-analysis indicates that medicinal plants may be used as topical or oral products, either alone or combined with other forms of treatment. These products have the potential to greatly improve the quality of life of the patienten_US
dc.identifier.affiliationsPontifical Catholic University of Campinas (PUC-Campinas), Center for Life Sciences, Postgraduate Program in Health Sciences, Campinas, São Paulo, Brazil.en_US
dc.identifier.citationGonçalves, Gisele MSen_US
dc.identifier.citationWenceslau, Laina Ren_US
dc.identifier.citationMendonça, Jose Alexandre. The use of medicinal plants for the treatment of psoriasis: A systematic review and meta-analysis. Indian Journal of Dermatology, Venereology and Leprology. 2023 Aug; 89(4): 543-548en_US
dc.identifier.issn0973-3922
dc.identifier.issn0378-6323
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/223156
dc.languageenen_US
dc.publisherScientific Scholaren_US
dc.relation.issuenumber4en_US
dc.relation.volume89en_US
dc.source.urihttps://doi.org/10.25259/IJDVL_46_2022en_US
dc.subjectMedicinal plantsen_US
dc.subjectpsoriatic plaqueen_US
dc.subjectskinen_US
dc.subjectclinical studiesen_US
dc.subjectIndigo naturalisen_US
dc.titleThe use of medicinal plants for the treatment of psoriasis: A systematic review and meta-analysisen_US
dc.typeJournal Articleen_US
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