The use of medicinal plants for the treatment of psoriasis: A systematic review and meta-analysis

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IJDVL2023v89n4p543.pdf (1.01 MB)
Date
2023-08
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Scientific Scholar
Abstract
Background: Psoriasis is a chronic inflammatory disease that presents as scaly patches on the skin that affects about 3% of the world's population. Adherence to treatment and discrimination against people are common problems, adversely impacts quality of life. Objectives: The aim of this study was to investigate the use of medicinal plants as therapeutic adjuvants in the treatment of plaque psoriasis through a systematic review and meta-analysis. Methods: A systematic review and meta-analysis of randomized controlled trials in patients with plaque psoriasis was carried out, comparing the efficacy of herbal treatments alone or in association with other therapies. The search was performed in the databases of The Cochrane Library, Lilacs, Medline via PubMed and Embase, only including studies published from 2016 to 2020.The certainty of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework. A systematic review and meta-analysis of randomized controlled trials (RCT) in patients with plaque psoriasis was carried out, comparing the efficacy of herbal treatments alone or in association with other therapies. We comprehensively searched the MEDLINE, Embase, Lilacs and Cochrane Library databases, only including studies published from 2016 to 2020. The certainty of evidence was assessed using the GRADE approach. Results: Out of 2,268 articles evaluated, only seven RCT were eligible for final analysis. Five of these studies evidenced low risk of bias and a high level of evidence. Limitations: Few RCT of medicinal plants. Conclusion: This meta-analysis indicates that medicinal plants may be used as topical or oral products, either alone or combined with other forms of treatment. These products have the potential to greatly improve the quality of life of the patient
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Keywords
Medicinal plants, psoriatic plaque, skin, clinical studies, Indigo naturalis
Citation
Gonçalves, Gisele MS
Wenceslau, Laina R
Mendonça, Jose Alexandre. The use of medicinal plants for the treatment of psoriasis: A systematic review and meta-analysis. Indian Journal of Dermatology, Venereology and Leprology. 2023 Aug; 89(4): 543-548
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https://imsear.searo.who.int/handle/123456789/223156
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Indian Journal of Dermatology, Venereology and Leprology