Galanin regulation of LH release in male rats.

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dc.contributor.authorPandit, Manisha Arora
dc.contributor.authorSaxena, R N
dc.date.accessioned2013-02-11T04:08:34Z
dc.date.available2013-02-11T04:08:34Z
dc.date.issued2010-06
dc.description.abstractThe present study examines the role of cerebroventricular administered (IIIrd ventricle) galanin on LHRH and LH release in adult and immature male rats. In both age groups, galanin stimulated LHRH synthesis and release from the hypothalamus, leading to a higher release of pituitary LH which in turn increased plasma LH levels. Galantide, a galanin receptor blocker, on the other hand, drastically reduced hypothalamic LHRH and plasma LH while increasing pituitary LH. In vitro incubation of anterior pituitary cells with galanin followed by LHRH resulted in increased release of pituitary LH but not by galanin alone. Galantide exhibited no such effect either alone or with LHRH. These results indicate that galanin is an important regulator for both hypothalamic LHRH and hypophysial LH and its role is independent of age in the case of male rats.en_US
dc.identifier.citationPandit Manisha Arora, Saxena R N. Galanin regulation of LH release in male rats. Indian Journal of Experimental Biology. 2010 June; 48(6): 544-548.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/145004
dc.language.isoenen_US
dc.source.urihttps://nopr.niscair.res.in/handle/123456789/9082en_US
dc.subjectGalaninen_US
dc.subjectGalantideen_US
dc.subjectLHRHen_US
dc.subjectLHen_US
dc.subjectNeuropeptideen_US
dc.titleGalanin regulation of LH release in male rats.en_US
dc.typeArticleen_US
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