Measurement of Serum Free Thyroxine by RIA in Normal Populations and During Pregnancy

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dc.contributor.authorWasana Lueprasitsakulen_US
dc.contributor.authorPichai Lueprasitsakulen_US
dc.contributor.authorPanadda Bangprathaiyaen_US
dc.contributor.authorPenpun Bhuripanyoen_US
dc.date.accessioned2011-02-24T04:34:25Z
dc.date.available2011-02-24T04:34:25Z
dc.date.created2010-05-08en_US
dc.date.issued2010-05-08en_US
dc.description.abstractSerum Free thyroxine (FT4) concentrations have been variously reported as either constant or falling in pregnancy. In this study , 177 serum samples from apparently normal preggnancies were used to derive trimester related euthyroid ranges throughout pregnancy for free T4 measured by Diagnostic Products and Amersham kits. Serum free T4 concentrations as determined by Amersham kits were shown to be significantly reduced in the second and third trimester (P\>0.05) . The free T4  concentrations measured by Diagnostic Products Kits fell with increasing gestational age especically in the third trimester, but the range of values were not significantly reduced from normal non-pregnant women. The observation that serum FT4 concentrations may fall as gestation progressed , as demonstrated by both the Amersham and Diagnostic Products radioimmunoassay technique, suggests that diagnosis and management thyroid disorders in pregnancy, tricester related reference ranges for FT4 must be used in pregnancy if the test is to correctly interpreted.en_US
dc.identifier.citationSrinagarind Medical Journal (SMJ); Vo. 4 No. 2 April - June 1989; 77-82en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/133798
dc.language.isoen_USen_US
dc.publisherFaculty of Medicine, Khon Kaen Universityen_US
dc.rightsAcademic Affairs, Faculty of Medicine, Khon Kaen University, KhonKaen, Thailanden_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/SMJ/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/SMJ/article/view/3639en_US
dc.titleMeasurement of Serum Free Thyroxine by RIA in Normal Populations and During Pregnancyen_US
dc.typeOriginal Articlesen_US
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