Erythrocytic glutathione peroxidase and lipid peroxidation in chronic renal failure patients.

Simple item page
dc.contributor.authorKhanyok, S
dc.contributor.authorLiammongkolkul, S
dc.contributor.authorCharoensak, Suwit
dc.contributor.authorOngajyooth, S
dc.contributor.authorOngajyooth, L
dc.date.accessioned2012-04-17T09:27:52Z
dc.date.available2012-04-17T09:27:52Z
dc.date.issued1997-08
dc.description.abstractGlutathione peroxidase (GPx) plays an important role in scavenging reactive oxygen metabolites and preventing the oxidative stress in the body. The purpose of this study is to investigate the levels of erythrocytic GPx activity and plasma malondialdehyde (MDA) in 25 chronic renal failure patients compared with 25 normal controls. The GPx activity in chronic renal failure patients was significantly lower than controls (22.6 + 5.5 U/gHb as 30.5 + 9.5 U/gHb respectively, p = 0.0033) and plasma malondialdehyde was significantly high in chronic renal failure patients compared to controls (78.89 + 55.38 ตmol/l vs 7.71 + 3.26 ตmol/l respec-tively, p< 0.0001). Lipid peroxidation product (MDA) correlated significantly with hemoglobin, hematorit, serum creatinine and creatinine clearance. Glutathione peroxidase also correlated significantly with serum creztinine. It was concluded that a decrease in reactive oxygen metabolite scavngers and increase in lipid peroxidation might contribute to might contribute to increase hemolysis and anemia in chronic renal failure.en_US
dc.identifier.citationKhanyok S, Liammongkolkul S, Charoensak Suwit, Ongajyooth S, Ongajyooth L. Erythrocytic glutathione peroxidase and lipid peroxidation in chronic renal failure patients. Siriraj Medical Journal, 1997 Aug; 49(8): 758-762.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/137717
dc.language.isoenen_US
dc.source.urihttps://www.sirirajmedj.com/content_download.php?content_id=581en_US
dc.subjectErythrocytic giutathione peroxidaseen_US
dc.subjectLipid peroxidationen_US
dc.subjectChronic renal failureen_US
dc.titleErythrocytic glutathione peroxidase and lipid peroxidation in chronic renal failure patients.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
smj1997v49n8p758.pdf
Size:
636 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Siriraj Medical Journal