Studies on stibanate resistant Leishmania donovani isolates of Indian origin.

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dc.contributor.authorPal, Sen_US
dc.contributor.authorMandal, Aen_US
dc.contributor.authorDuttagupta, Sen_US
dc.date.accessioned2009-05-28T10:52:34Z
dc.date.available2009-05-28T10:52:34Z
dc.date.issued2001-03-10en_US
dc.description.abstractStudies with 26 clones of L. donovani promastigotes derived from three different Indian isolates indicated that wild type parasites are mixture of stibanate sensitive and resistant cells. Both forms of the parasite were resistant to the drug. Infection with resistant parasites appears to be the primary reason of high rate of pentavalent antimony unresponsiveness among Indian kala-azar patients. It was observed that the resistant parasites originated as a result of irregular and often incomplete treatment of kala-azar patients with pentavalent antimonials.en_US
dc.description.affiliationLeishmania Division, Indian Institute of Chemical Biology, Calcutta.en_US
dc.identifier.citationPal S, Mandal A, Duttagupta S. Studies on stibanate resistant Leishmania donovani isolates of Indian origin. Indian Journal of Experimental Biology. 2001 Mar; 39(3): 249-54en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/55922
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntimony Sodium Gluconate --pharmacologyen_US
dc.subject.meshAntiprotozoal Agents --pharmacologyen_US
dc.subject.meshDrug Resistanceen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshLeishmania donovani --drug effectsen_US
dc.subject.meshLeishmaniasis, Visceral --drug therapyen_US
dc.titleStudies on stibanate resistant Leishmania donovani isolates of Indian origin.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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