Clinical Profile and Outcome of Swine Flu in Indian Children.

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dc.contributor.authorDas, Rashmi Ranjan
dc.contributor.authorSami, Abdus
dc.contributor.authorLodha, Rakesh
dc.contributor.authorJain, Richa
dc.contributor.authorBroor, S
dc.contributor.authorKaushik, S
dc.contributor.authorSingh, B B
dc.contributor.authorAhmed, M
dc.contributor.authorSeth, Rachna
dc.contributor.authorKabra, Sushil K
dc.date.accessioned2015-12-22T09:55:53Z
dc.date.available2015-12-22T09:55:53Z
dc.date.issued2011-05
dc.description.abstractObjective: To describe the clinical characteristics and outcome of Indian children infected with 2009 H1N1 influenza virus. Study design: Retrospective chart review. Setting: Outpatient department and hospitalized patients in a tertiary care hospital. Methods: Clinical details of 85 children (positive for the 2009 H1N1 virus infection tested by real-time reversetranscriptase– polymerase-chain-reaction assay) were analyzed from medical charts. Results: Of the 85 (55 boys) children positive for 2009 H1N1 virus infection, 64.7% were between 5 years to 16 years, and 35.3% were below 5 years age. The mean age of these children was 7.5±3.5 yr. Contact history was positive only in 22 (26%) cases. High grade fever was the most common symptom, followed by cough and rhinorrhea. Twenty-nine (34%) patients had an underlying co-morbid condition. Of the 34 patients who underwent chest radiography during evaluation, 18 children (52.9%) had findings consistent with lower respiratory tract infection. Antiviral therapy was initiated in 76 patients. Hospitalization was required in 30 (35.3%) children. Risk factors for hospitalization included underlying co-morbid condition, respiratory distress, vomiting, wheezing, diarrhea, hypotension and infiltrates/consolidation on chest radiograph. Mean length of hospitalization was 131+76 hours, irrespective of underlying disease. Three children developed Acute Respiratory Distress Syndrome and died. Conclusions: Clinical features and routine laboratory investigations in children with swine origin influenza were non-specific. Children with co-morbid condition, respiratory distress, vomiting, wheezing, diarrhea, hypotension and infiltrates/consolidation on chest radiograph were at higher risk of hospitalization.en_US
dc.identifier.citationDas Rashmi Ranjan, Sami Abdus, Lodha Rakesh, Jain Richa, Broor S, Kaushik S, Singh B B, Ahmed M, Seth Rachna, Kabra Sushil K. Clinical Profile and Outcome of Swine Flu in Indian Children. Indian Pediatrics. 2011 May; 48(5): 373-378.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/168833
dc.language.isoenen_US
dc.source.urihttps://www.indianpediatrics.net/may2011/may-373-378.htmen_US
dc.subjectAcute lung injuryen_US
dc.subjectARDSen_US
dc.subjectH1N1 influenzaen_US
dc.subjectPandemic influenzaen_US
dc.subjectSwine origin influenzaen_US
dc.titleClinical Profile and Outcome of Swine Flu in Indian Children.en_US
dc.typeArticleen_US
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