Effect of arsenic on cell growth of the cellular slime mould, Dictyostelium discoideum.

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dc.contributor.authorMukhopadhyay, Sen_US
dc.contributor.authorChatterjee, Sen_US
dc.date.accessioned2009-05-28T12:54:31Z
dc.date.available2009-05-28T12:54:31Z
dc.date.issued2003-11-31en_US
dc.description.abstractThe growing D. discoideum cells were killed in a dose-dependent manner when exposed to 100 and 140 ppm of arsenic (As2O3) at mid-log phase for 20 min. Reduced plaque sizes and changed cell and colony morphologies were observed in the treated cells. Endocytotic functions (both phagocytosis and pinocytosis) were also inhibited in the treated cells. Arsenic treated cell showed a lower DNA and protein synthetic activities. These findings are discussed in relation to known mechanism of action of the heavy metal on growth-related cellular functions.en_US
dc.description.affiliationSchool of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.en_US
dc.identifier.citationMukhopadhyay S, Chatterjee S. Effect of arsenic on cell growth of the cellular slime mould, Dictyostelium discoideum. Indian Journal of Experimental Biology. 2003 Nov; 41(11): 1300-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/58710
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshArsenic --toxicityen_US
dc.subject.meshCell Division --drug effectsen_US
dc.subject.meshDNA --metabolismen_US
dc.subject.meshDictyostelium --cytologyen_US
dc.subject.meshEndocytosis --drug effectsen_US
dc.subject.meshPhagocytosis --drug effectsen_US
dc.subject.meshPinocytosis --drug effectsen_US
dc.subject.meshProteins --metabolismen_US
dc.titleEffect of arsenic on cell growth of the cellular slime mould, Dictyostelium discoideum.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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