Role Of Oral Pyridoxine (vitamin B6) Supplementation In The Reduction Of Hyperoxaluria And Prevention Of Recurrent Urolithiasis

Simple item page
dc.contributor.authorKowli, Mugdha S.en_US
dc.contributor.authorChakrabarti, Nilayen_US
dc.contributor.authorBhadre, Rohinien_US
dc.contributor.authorIndap, Shalakaen_US
dc.date.accessioned2019-11-25T05:21:44Z
dc.date.available2019-11-25T05:21:44Z
dc.date.issued2019-07
dc.description.abstractOur prospective, randomised controlled study was to assess the role of oral pyridoxine (Vitamin B6) supplementation in addition to standard dietary advice, compared against only dietary advice, in the reduction of urinary oxalate levels in patients with urinary calculi along with proven hyperoxaluria. 74 subjects were randomly divided into Interventional Group (n=38) who received oral Pyridoxine 40mg/day with dietary oxalate restriction and Control Group (n=36) who received only dietary oxalate restriction. Both groups were evaluated and statistically compared at the end of 3 months. Interventional group showed statistically significant (p = 0.0001) reduction in 24 hours urinary oxalate levels. Pyridoxine, cofactor in the alanine–glyoxalate–transaminase pathway converts glyoxalate to glycine and reduces oxalate production thereby decreasing hyperoxaluria, risk factor of urolithiasis. Oral Pyridoxine supplementation (40 mg/day) with dietary oxalate restriction can be a prophylactic measure for prevention of recurrence of calcium oxalate urolithiasis.en_US
dc.identifier.affiliationsFormer DNB Resident, Department of Surgery, K.J. Somaiya Medical College, Somaiya Ayurvihar, Sion, Mumbai, Maharashtra, India. Pincode – 400022en_US
dc.identifier.affiliationsProfessor, Department of Surgery, K.J. Somaiya Medical College, Somaiya Ayurvihar, Sion, Mumbai, Maharashtra, India. Pincode – 400022en_US
dc.identifier.affiliationsProfessor, Department of Biochemistry, K.J. Somaiya Medical College, Somaiya Ayurvihar, Sion, Mumbai, Maharashtra, India. Pincode – 400022en_US
dc.identifier.affiliationsAssociate Professor, Department of Surgery, K.J. Somaiya Medical College, Somaiya Ayurvihar, Sion, Mumbai, Maharashtra, India. Pincode – 400022en_US
dc.identifier.citationKowli Mugdha S., Chakrabarti Nilay, Bhadre Rohini, Indap Shalaka. Role Of Oral Pyridoxine (vitamin B6) Supplementation In The Reduction Of Hyperoxaluria And Prevention Of Recurrent Urolithiasis. Indian Journal of Applied Research. 2019 Jul; 9(7): 9-10en_US
dc.identifier.issn2249-555X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/185135
dc.languageenen_US
dc.publisherWorld Wide Journalsen_US
dc.relation.issuenumber7en_US
dc.relation.volume9en_US
dc.subjectHyperoxaluriaen_US
dc.subjectpyridoxine Supplementationen_US
dc.subjectprevention Of Recurrent Urolithiasisen_US
dc.titleRole Of Oral Pyridoxine (vitamin B6) Supplementation In The Reduction Of Hyperoxaluria And Prevention Of Recurrent Urolithiasisen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijar2019v9n7p9.pdf
Size:
653.36 KB
Format:
Adobe Portable Document Format
Download
Collections
Indian Journal Of Applied Research